专利检索 ap:"Babu, Yarlagadda S." 第 1 页

1.

发明公开
TETRAHYDROFURO Ý3 4-D¨DIOXOLANE COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS AND CANCER 有权
标题翻译：四氢[3,4-D]二氧戊环FOR USE IN病毒感染和癌症的治疗

公开(公告)号：EP2155758A1

公开(公告)日：2010-02-24

申请号：EP08747850.9

申请日：2008-05-08

申请人： BIOCRYST PHARMACEUTICALS, INC. , Babu, Yarlagadda S. , Chand, Pooran

发明人： BABU, Yarlagadda, S. , CHAND, Pooran

IPC分类号： C07D519/00 , A61K31/519 , A61P35/00 , A61P31/12

CPC分类号： C07D519/00

摘要： The invention provides compounds of formula (I), as described herein, or pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of formula (I) are useful as anti-viral agents and/or as anti-cancer agents.

2.

发明公开
METHODS OF TREATING HEMATOLOGIC CANCERS USING PNP INHIBITORS SUCH AS FORODESINE IN COMBINATION WITH ALKYLATING AGENTS OR ANTI-CD20 AGENTS 审中-公开
标题翻译：方法血癌与PNP抑制剂如治疗烷化剂或抗CD20基金FORODESIN合用

公开(公告)号：EP2237778A2

公开(公告)日：2010-10-13

申请号：EP08860419.4

申请日：2008-12-10

申请人： BIOCRYST PHARMACEUTICALS, INC. , Bantia, Shanta , Breitfeld, Philip , Babu, Yarlagadda S.

发明人： BANTIA, Shanta , BREITFELD, Philip , BABU, Yarlagadda, S.

IPC分类号： A61K31/4184 , A61K31/4745 , A61K39/395 , A61K45/06 , A61K35/00 , A61P35/02

CPC分类号： A61K31/519 , A61K31/4184 , A61K31/7076 , A61K39/39541 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/545 , C07K16/2887 , A61K2300/00

摘要： The present application relates to treatment of hematologic cancers, which treatments can include, e.g., administration of a purine nucleoside phosphorylase (PNP) inhibitor, an alkylating agent and/or an anti-CD20 agent, and related compositions and kits.

摘要翻译： 本申请涉及治疗血液癌症，其中处理可以包括，例如，嘌呤核苷磷酸化酶（PNP）抑制剂的给药，烷化剂和/或抗CD20剂，以及相关组合物和试剂盒。