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1.发明公开
公开(公告)号：EP4374862A1
公开(公告)日：2024-05-29
申请号：EP22846065.5
申请日：2022-06-27
发明人： YOON, Yoo Sik , SIM, In Ae , LEE, Jong Kyu , LIM, Hye Mi
IPC分类号： A61K31/7048 , A61K36/65 , A61P21/00 , A23L33/125
CPC分类号： A61K36/65 , A61K31/7048 , A61P21/00 , A23L33/125
摘要： The present invention relates to a pharmaceutical composition for preventing or treating cachexia and muscle loss containing paeoniflorin. The pharmaceutical composition containing paeoniflorin may be used to effectively prevent or treat cachexia and muscle loss.
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公开(公告)号：EP3760215A1
公开(公告)日：2021-01-06
申请号：EP19761453.0
申请日：2019-02-28
发明人： YOON, Yoo Sik , JANG, Jae Woong , CHAE, Se Yeon , BAE, Tae Hyun , LEE, Hyun Ji , SONG, Jae Won
IPC分类号： A61K36/65 , A23L33/105 , A61P35/00
摘要： The present disclosure relates to a composition containing a Paeoniae radix extract as an active ingredient. The composition may alleviate inappetence, weight loss, muscle loss and fatigue and inhibit hematopoietic toxicity. Thus, the composition may be effectively used for the prevention, alleviation or treatment of cachexia and muscle loss.
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公开(公告)号：EP3712518A1
公开(公告)日：2020-09-23
申请号：EP20160848.6
申请日：2020-03-04
发明人： JEON, Jongkeon , CHUNG, Haeyoong , KANG, Jiyoung , LEE, David Kangseong , KWAK, Daeyoung , PARK, Sohee
摘要： An air purifying system may include at least three air cleaners or purifiers capable of independently operating and a docking station to support the at least three air purifiers. Since the air purifiers may be separated or stacked together on the docking station, the air purifying system may be operated in various states desired by a user.
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公开(公告)号：EP3712514A1
公开(公告)日：2020-09-23
申请号：EP20164348.3
申请日：2020-03-19
发明人： KANG, Jiyoung , CHUNG, Haeyoong , JEON, Jongkeon , LEE, David Kangseong , KWAK, Daeyoung , PARK, Sohee
IPC分类号： F24F1/0071 , A47L9/28 , F24F3/16 , F24F11/30 , F24F11/89
摘要： An air purifying system includes a robot cleaner configured to generate map information during vacuum cleaning and at least one air purifier that is operated based on the generated map information. Air purifying is performed using updated map information acquired by the robot cleaner during cleaning. The at least one air purifier includes two portable air purifiers mounted on a base air purifier. The two portable air purifiers are configured to be lifted from the base air purifier and moved to separate indoor rooms. The base air purifier includes a controller that determines, based on the generated map information and other information, which rooms the two portable air purifiers should be placed in so that air purifying may be efficient.
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公开(公告)号：EP2995300B1
公开(公告)日：2020-04-22
申请号：EP13875242.3
申请日：2013-12-19
发明人： LEE, Kangseok , BAE, Jeehyeon , SEONG, Maeng Je , HAN, Min Su , YEOM, Ji Hyun , RYOU, Sang Mi , HA, Nam Chul
IPC分类号： A61K47/54 , A61K47/69 , A61P35/00 , A61K38/00 , C12N15/115
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6.发明公开
公开(公告)号：EP3546428A1
公开(公告)日：2019-10-02
申请号：EP18849998.2
申请日：2018-08-28
发明人： SUNG, Da Young , KIM, Myung Gil , JANG, Minchul , HWANG, Hyewon
IPC分类号： C01G51/00 , C01B21/082 , C01B21/097 , H01M4/36 , H01M4/62 , H01M4/587 , H01M10/052
摘要： A method for preparing a negative electrode active material, a negative electrode active material prepared using the same, and a lithium secondary battery, and in particular, to a method for preparing a negative electrode active material including the steps of (a) preparing a coating composition including a precursor of metal-phosphorous-oxynitride; (b) forming a precursor layer on a negative electrode active material with the coating composition of (a) using a solution process; and (c) forming a metal-phosphorous-oxynitride protective layer on the negative electrode active material by heat treating the negative electrode active material having the precursor layer formed thereon. The method for preparing a negative electrode active material uses a solution process, which is advantageous in terms of simplifying the whole process and reducing costs, and high capacity, high stabilization and long lifetime are obtained as well by the formed protective layer having excellent properties.
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公开(公告)号：EP2979696B1
公开(公告)日：2019-05-08
申请号：EP14772608.7
申请日：2014-03-27
发明人： BAE, Jee Hyeon , LEE, Kang Seok , KIM, Jaehong
IPC分类号： A61K31/40 , A61K31/404 , A61K31/4035 , A61P35/00 , A61K31/426
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8.发明公开PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, CONTAININGLACTOCOCCUS CHUNGANGENSIS 审中-公开用于预防或治疗炎性疾病的药物组合物，含有肺孢子虫
公开(公告)号：EP3275450A2
公开(公告)日：2018-01-31
申请号：EP16773374.0
申请日：2016-03-25
发明人： KIM,Won Yong , CHOI, Woo Jin
IPC分类号： A61K35/74 , A61K35/742
CPC分类号： A61K35/74 , A61K8/99 , A61K35/744 , A61Q19/00 , A61Q19/007 , C12N1/20 , C12R1/46 , Y02A50/40 , Y02A50/401 , Y02A50/473 , Y02A50/481
摘要： The composition according to the present invention, which comprises Lactococcus chungangensis as an active ingredient, has excellent effects of preventing or treating inflammatory diseases, inhibiting the secretion of nitric oxide and prostaglandin E 2 , which are major inflammatory factors, and inhibiting the secretion of β-hexosaminidase and histamine, which are major factors related to allergies, and also significantly suppressing the production of skin disease-related cytokines and chemokines. Such effects are at the same level as those of conventional skin disease therapeutic agents (tacrolimus), and thus the composition can be used as a preventive or therapeutic agent against inflammatory diseases. In addition, the composition according to the present invention exhibits an antibacterial activity against Staphylococcus aureus, which is a microorganism inducing a secondary infection of atopic dermatitis and the like, and thus can be used in preventing or treating a bacterial infection.
摘要翻译： 本发明的含有乳酸球菌作为活性成分的组合物具有预防或治疗炎性疾病，抑制作为主要炎症因子的一氧化氮和前列腺素E2的分泌， 氨基己糖苷酶和组胺，它们是与变态反应有关的主要因素，并且也显着抑制皮肤病相关细胞因子和趋化因子的产生。 这些效果与常规皮肤疾病治疗剂（他克莫司）的效果相同，因此该组合物可以用作针对炎性疾病的预防或治疗剂。 另外，本发明的组合物对作为诱发特应性皮炎等的继发感染的微生物的金黄色葡萄球菌表现出抗菌活性，因此可用于预防或治疗细菌感染。
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9.发明公开PROTEIN TRANSDUCTION DOMAIN BASED ON GOLD NANOPARTICLE-APTAMER CONJUGATE AND METHOD FOR PRODUCING SAME 审中-公开蛋白转导基于其制造GOLDNANOPARTIKELAPTAMERKONJUGATS和方法
公开(公告)号：EP2995300A1
公开(公告)日：2016-03-16
申请号：EP13875242.3
申请日：2013-12-19
发明人： LEE, Kangseok , BAE, Jeehyeon , SEONG, Maeng Je , HAN, Min Su , YEOM, Ji Hyun , RYOU, Sang Mi , HA, Nam Chul
IPC分类号： A61K9/16 , A61K9/14 , A61K47/48 , C12N15/115
摘要： The present invention relates to a protein transduction domain comprising gold nanoparticles and aptamers binding to the surfaces of the gold nanoparticles. The protein transduction domain according to the present invention is expected to be useful for diagnosing or treating diseases since the protein transduction domain specifically binds to proteins, which are to be delivered by various tagged aptamers or protein-specific aptamers binding to gold nanoparticles, thereby effectively delivering the proteins into cells, can be harmless to humans by using gold nanoparticles having very little cytotoxicity, and allows easy confirmation of the intercellular position thereof by reflecting lights of various wavelengths.
摘要翻译： 本发明涉及一种蛋白质转导结构域包含金纳米颗粒和适体结合的金纳米颗粒的表面上。 蛋白转导域雅丁到，本发明预期可用于诊断或治疗疾病，因为所述蛋白转导结构域特异性结合蛋白，其是通过各种标记的适体或蛋白质特异性的适体结合的金纳米颗粒被输送，从而有效地有用 递送蛋白到细胞中，可以通过使用具有非常小的细胞毒性的金纳米颗粒对人体无害，并且其通过反映各种波长的光允许细胞间位置的容易确认。
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公开(公告)号：EP4349364A1
公开(公告)日：2024-04-10
申请号：EP22816408.3
申请日：2022-05-30
发明人： KIM, Dae Kyong
摘要： The present invention relates to a composition for repairing vascular degeneration and vascular injuries and preventing or treating vascular diseases, containing hyaluronan and proteoglycan link protein 1 (HAPLN1) as an active ingredient. More specifically, provided is a pharmaceutical composition and a health functional food composition for preventing or treating vascular diseases, containing HAPLN1 as an active ingredient. HAPLN1 inhibits and alleviates, in blood vessel walls, damage to the elastin fiber layer and loss of transgelin, and effectively inhibits the phosphorylation of NF-κB or focal adhesion kinase (FAK) in vascular smooth muscle cells (VSMCs), and thus can be used for preventing, alleviating or treating vascular injuries and various diseases caused by aging or a high-fat diet.
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