摘要:
The present disclosure relates to an RNA aptamer and uses thereof, in particular, an aptamer which specifically bind to EpCAM and which demonstrates superior tumor penetrating ability.
摘要:
The present invention relates generally to a sample processing device, such as a microfluidic device, comprising a substrate, wherein the substrate comprises a plurality of channels configured to transport a fluid, and wherein the plurality of channels are substantially coated with lubricin, or a functional variant thereof. Also disclosed herein are methods of manufacturing such devices, methods of preventing fouling of a channel in a device using lubricin, or a functional variant thereof and methods of controlling the electrokinetic flow of an analyte through a channel that is substantially coated with lubricin, or a functional variant thereof. Also disclosed herein is chromatographic material for the electrophoretic and/or chromatographic separation of an analyte, wherein the chromatographic material is substantially coated with lubricin, or a functional variant thereof..
摘要:
The present invention relates generally to methods for the treatment and/or prophylaxis of neurological diseases and disorders involving administration of trans 10-HDA. In particular, the methods of the present invention are useful in the treatment and/or prophylaxis of acquired or progressive neurodevelopmental disorders and conditions in mammals. More particularly, methods are taught herein for the treatment and/or prophylaxis of diseases and disorders such as autism spectrum disorders.
摘要:
The present disclosure relates to RNA aptamers and uses thereof, in particular, aptamers which specifically bind to CD133 and which demonstrate superior tumour penetration.
摘要:
Un système de chauffage à micro-ondes comprend un support multifaces (1; 9 à 13) supportant une multiplicité d'applicateurs de micro-ondes (2 à 4; 14 à 18), un tube (8; 24a; 40) définissant une zone de traitement (T) pour contenir la matière à traiter, ainsi que des réflecteurs sensiblement concaves (5 à 7; 19 à 23) supportés dans chaque coin dudit support (1; 9 à 13) afin de réfléchirl'énergie des micro-ondes passant à travers ladite zone (T). Le tube (24a) est supporté rotativement et comprend des palettes (24c) pour agiter la matière se trouvant dans le tube (24a). Le tube est entouré par un tube extérieur (24a), et l'espace entre les tubes est rempli avec un matériau ayant des propriétés diélectriques dissemblables afin de provoquer l'adaptation des applicateurs de micro-ondes à la matière à traiter. Dans un autre mode de réalisation, on a prévu un moyen de chauffage d'une bande mobile (S), comprenant un ou plusieurs applicateurs (32) de micro-ondes adajcents à ladite bande (S), en-dessus ou en-dessous de cette dernière, de sorte que l'axe long de la configuration des micro-ondes (habituellement elliptique) produite par au moins un applicateur soit transversal au sens de déplacement de ladite bande (S).
摘要:
A firefighter training unit for simulating use of a fire extinguishing system, the unit including: a reel; a user-manipulable nozzle; a hose having opposite ends attached respectively to the reel and the nozzle and being partially wound around the reel, wherein rotation of the reel in a first rotational direction allows the hose to be unwound from the reel; a motor configured to drive the reel in a second rotational direction which causes the hose to be wound onto the reel; one or more devices for providing one or more output signals corresponding to one or more simulated operating conditions of the fire extinguishing system; and a controller configured to drive the motor in response to the one or more output signals so as to apply torque to the reel in the second rotational direction to simulate forces applied to the hose during operation of the fire extinguishing system.