公开(公告)号：EP2964184B1

公开(公告)日：2018-05-09

申请号：EP14759906.2

申请日：2014-03-04

申请人： Dermelle, Llc D/b/a Eternogen, LLC

发明人： DEVORE, Dale, P. ,  BROOKS, Robert, J. ,  BYRNE, Todd

IPC分类号： A61K8/65 ,  A61Q19/08 ,  A61K8/34 ,  A61K8/60 ,  A61K8/44 ,  A61L27/24 ,  A61L27/34 ,  A61L27/50 ,  C08L89/06

CPC分类号： A61L27/24 ,  A61K8/345 ,  A61K8/60 ,  A61K8/65 ,  A61K2800/95 ,  A61L27/34 ,  A61L27/505 ,  A61L27/54 ,  A61L2300/412 ,  A61L2400/06 ,  A61L2430/34 ,  A61Q19/08 ,  C08L89/06

摘要： The present invention is directed to injectable acid soluble collagen compositions comprising a neutralized solution of an acid soluble collagen, EDTA and preferably a polyol, wherein the composition is injectable at physiological pH and the acid soluble collagen polymerizes upon exposure to tissue. The invention is suitable for use in soft tissue augmentation, promoting soft tissue regeneration and coating medical implants and devices.

公开(公告)号：EP2964184A4

公开(公告)日：2016-12-07

申请号：EP14759906

申请日：2014-03-04

申请人： DERMELLE LLC D/B/A ETERNOGEN LLC

发明人： DEVORE DALE P ,  BROOKS ROBERT J ,  BYRNE TODD

IPC分类号： A61K8/65 ,  A61K8/34 ,  A61K8/44 ,  A61K8/60 ,  A61L27/24 ,  A61Q19/08

CPC分类号： A61L27/24 ,  A61K8/345 ,  A61K8/60 ,  A61K8/65 ,  A61K2800/95 ,  A61L27/34 ,  A61L27/505 ,  A61L27/54 ,  A61L2300/412 ,  A61L2400/06 ,  A61L2430/34 ,  A61Q19/08 ,  C08L89/06

摘要： The present invention is directed to injectable acid soluble collagen compositions comprising a neutralized solution of an acid soluble collagen, EDTA and preferably a polyol, wherein the composition is injectable at physiological pH and the acid soluble collagen polymerizes upon exposure to tissue. The invention is suitable for use in soft tissue augmentation, promoting soft tissue regeneration and coating medical implants and devices.

公开(公告)号：EP2964184A1

公开(公告)日：2016-01-13

申请号：EP14759906.2

申请日：2014-03-04

申请人： Dermelle, Llc D/b/a Eternogen, LLC

发明人： DEVORE, Dale, P. ,  BROOKS, Robert, J. ,  BYRNE, Todd

IPC分类号： A61K8/65 ,  A61Q90/00

CPC分类号： A61L27/24 ,  A61K8/345 ,  A61K8/60 ,  A61K8/65 ,  A61K2800/95 ,  A61L27/34 ,  A61L27/505 ,  A61L27/54 ,  A61L2300/412 ,  A61L2400/06 ,  A61L2430/34 ,  A61Q19/08 ,  C08L89/06

摘要： The present invention is directed to injectable acid soluble collagen compositions comprising a neutralized solution of an acid soluble collagen, EDTA and preferably a polyol, wherein the composition is injectable at physiological pH and the acid soluble collagen polymerizes upon exposure to tissue. The invention is suitable for use in soft tissue augmentation, promoting soft tissue regeneration and coating medical implants and devices.

摘要翻译： 本发明涉及可注射酸溶胶原组合物，其包含酸可溶胶原，EDTA和优选多元醇的中和溶液，其中所述组合物在生理pH下可注射，并且所述酸可溶胶原在暴露于组织时聚合。 本发明适用于软组织再生，促进软组织再生和涂覆医学植入物和装置。