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公开(公告)号：EP4397816A1
公开(公告)日：2024-07-10
申请号：EP22880734.3
申请日：2022-09-21
IPC分类号： E02F9/26
CPC分类号： E02F9/26
摘要： A bucket information acquisition device (5) for acquiring information regarding the shape of a bucket that rotates about a rotational center axis along a predetermined moving plane in a construction machine includes: a distance distribution acquisition unit (63) that acquires the three-dimensional distance distribution of the bucket with respect to a reference point; a reference cross section extraction unit (502) that extracts, from the distance distribution acquired by the distance distribution acquisition unit, a reference cross section which is a cross section of the bucket obtained by cutting the bucket along a plane parallel to the moving plane; an approximate line identification unit (503) that identifies, based on the reference cross section, an approximate line approximating the reference cross section composed of a straight line and a curve; and a bucket shape calculation unit (504) that calculates bucket shape information regarding the shape of the bucket based on the approximate line.
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2.发明公开
公开(公告)号：EP4389990A1
公开(公告)日：2024-06-26
申请号：EP22875425.5
申请日：2022-03-31
发明人： SEKIZUKA, Ryota , ITO, Masaru , KURITA, Yuichi
摘要： Provided is a system and the like that can improve operability of a manipulation mechanism for an operator. Manipulation reaction forces f1(θ) and f2(ϕ) acting on manipulation levers 2111 and 2112 are controlled by controlling operation of actuators 214. At this time, the manipulation reaction forces f1(θ) and f2(ϕ) are controlled to cause reaction forces F1(θ) and F2(ϕ) in manipulation directions opposite to each other perceived by the operator through manipulation levers 2111 and 2112 (manipulation mechanism) to realize symmetry about a manipulation amount of zero, within a manipulation amount range in a positive manipulation direction and a manipulation amount range in a negative manipulation direction.
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公开(公告)号：EP4339380A1
公开(公告)日：2024-03-20
申请号：EP22832581.7
申请日：2022-04-21
摘要： Provided is a construction machine that is capable of preventing degradation in efficiency of excavation work while preventing an increase in excavation resistance in the excavation work. A controller (50) of a construction machine (10) determines an accommodation state of earth and sand accommodated in a bucket (6), and outputs a resistance reduction command signal that is a command signal for operating a work device (3) such that the bucket (6) is displaced in a resistance reduction direction (D2, D3, D4) that is a direction where excavation resistance acting on the bucket (6) is capable of being reduced, in accordance with a result of determining the accommodation state.
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公开(公告)号：EP4116709A1
公开(公告)日：2023-01-11
申请号：EP21814369.1
申请日：2021-05-14
发明人： FUNABASHI, Hisakage , KURODA, Akio , SATO, Hiroya
IPC分类号： G01N33/483 , G01N33/53 , G01N33/543 , G01N33/566 , G01N27/02
摘要： The invention provides a method capable of detecting a trace amount of insulin contained in a sample.
The invention relates to an insulin detection method including: adding a sample to an electrode having an insulin binding protein immobilized on a surface of the electrode, the insulin binding protein specifically recognizing a site of insulin; and detecting an electrochemical change associated with formation of a complex of the insulin and the insulin binding protein. The insulin binding protein includes a first region that includes an α-CT segment of an insulin receptor and does not include a β subunit of the insulin receptor and a second region that includes an L1 domain of the insulin receptor and does not include the β subunit of the insulin receptor, and one of the first region and the second region is immobilized on the surface of the electrode.-
公开(公告)号：EP4053346A1
公开(公告)日：2022-09-07
申请号：EP20901434.9
申请日：2020-11-30
发明人： ITO Masaru , KURITA Yuichi
摘要： To provide a remote operation device and a remote operation system that can reduce or eliminate deviation of the position of an indicator image of a working unit such as a line image in an image with respect to the position of the working unit in a real space. In a remote operation device 20, an indicator image Img2 is generated and, then, superimposed on a work environment image Img1 and output to an image output device 221. In some case, a position posture coordinate value of a working unit corresponding to captured image data in a work environment image discontinuously changes because of a cause such as a communication failure between the remote operation device 20 and a working machine 40 due to a transmission delay of captured image data and deviates from a position posture coordinate value of the working unit estimated according to an operation form of a remote operation mechanism 211. In this case, a semitransparent indicator image Img2(τ2) simulating a bucket 445 is superimposed on a work environment image Img1(τ2) in a position where the bucket 445 is estimated to be originally present and deviating from an image region representing the bucket 445, and output to the image output device 221.
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6.发明公开
公开(公告)号：EP4035670A1
公开(公告)日：2022-08-03
申请号：EP20867960.5
申请日：2020-09-25
发明人： KATO, Yukio , MAEDA, Satoshi , TSUJI, Koichiro , SHAO, Jin Chang , NAKASHIMA, Ayumu , MASAKI, Takao , DOI, Shigehiro , ISHIUCHI, Naoki
IPC分类号： A61K35/28 , A61K48/00 , A61P1/02 , A61P1/16 , A61P3/10 , A61P9/10 , A61P11/00 , A61P11/04 , A61P13/12 , A61P17/02 , A61P19/02 , A61P19/08 , A61P25/00 , A61P25/28 , A61P27/02 , A61P35/00 , A61P37/02 , A61P43/00 , C12N1/00 , C12N5/0775 , C12Q1/6837
摘要： The present invention provides a novel repair agent for damaged tissue that brings about a notably high effect of repairing damaged tissue, as compared with conventional repair agents for damaged tissue, and a method for producing such a repair agent. A method for producing a repair agent for damaged tissue of the present invention includes the step of culturing mesenchymal stem cells in a serum-free medium at an oxygen concentration of less than 5%.
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公开(公告)号：EP3835444A1
公开(公告)日：2021-06-16
申请号：EP19847666.5
申请日：2019-07-09
发明人： SUGIO, Kenjiro , TAKAHASHI, Takuya , SAWADA, Hitoshi , SASAKI, Gen , MATSUGI, Kazuhiro , CHOI, Yongbum , XU, Zhefeng , SUETSUGU, Hajime , KONDO, Hiroki , MANABE, Hideki , YAMANE, Kyotaro , HATAKEYAMA, Kenichi , KAWASAKI, Keizo , ITAOKA, Tsuyoshi , SENO, Shinsaku , TAMURA, Yasushi , INO, Ichirou , HIRAO, Yoshihide
摘要： Provided is a method of producing a composite having high strength and high thermal conductivity. The method includes: an alloy preparation step including preparing an alloy which is a solid solution containing α-Fe as a solvent and at least one type of α-phase stabilizing element as a solute; a first mixing step including mixing at least one type of α-phase stabilizing element in powder form and SiC to prepare a first mixture; a second mixing step including mixing the alloy and the first mixture to prepare a second mixture; and a sintering step including sintering the second mixture.
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8.发明公开
公开(公告)号：EP3835443A1
公开(公告)日：2021-06-16
申请号：EP19846080.0
申请日：2019-07-24
发明人： MATSUGI, Kazuhiro , KE, Yujiao , XU, Zhefeng , SUGIO, Kenjiro , CHOI, Yongbum , SASAKI, Gen , SUETSUGU, Hajime , KONDO, Hiroki , MANABE, Hideki , YAMANE, Kyotaro , HATAKEYAMA, Kenichi , KAWASAKI, Keizo , ITAOKA, Tsuyoshi , SENO, Shinsaku , TAMURA, Yasushi , INO, Ichirou , HIRAO, Yoshihide
摘要： Provided is a Fe-based sintered body which has both of a high hardness and a high thermal conductivity and which can be more stably produced. The Fe-based sintered body includes: a matrix (1) containing Fe as a main component; and a hard phase (4) dispersed in the matrix (1). The matrix (1) is formed in a network shape and contains αFe. The hard phase (4) contains TiC.
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公开(公告)号：EP3831928A1
公开(公告)日：2021-06-09
申请号：EP19857860.1
申请日：2019-09-06
发明人： SAKAMOTO, Atsushi , OKAZAKI, Kumiko , YAMAMOTO, Takashi , OHTA, Hiroyuki , HORI, Koichi , SHIMIZU, Shinsuke , TAKAMI, Akihide , NOMURA, Seiji , SAITO, Fumihiko
摘要： A microorganism having at least one SPX gene encoding SPX protein responsive to phosphorus deficiency, and characterized in that a function of the SPX protein is decreased or lost by introducing gene mutation into the SPX gene.
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公开(公告)号：EP3725881A1
公开(公告)日：2020-10-21
申请号：EP18888263.3
申请日：2018-12-13
申请人： Hiroshima University
发明人： TAHARA, Hidetoshi
IPC分类号： C12N15/113 , C12Q1/68 , G01N33/50
摘要： The present invention aims at providing a method of assisting the detection of pancreatic cancer with high accuracy. The present invention provides a method of assisting the detection of pancreatic cancer, which includes using as an index the abundance of at least one of miRNAs, isoform miRNAs (isomiRs), precursor miRNAs, transfer RNA fragments (tRFs), or non-coding RNA fragments (MiscRNAs) contained in a test sample isolated from a living body, whose nucleotide sequence is represented by any one of SEQ ID NOs: 1, 4, 6 to 10, 12, 15, 17, 19 to 21, 2, 3, 5, 11, 13, 14, 16, 18, and 22 to 38, wherein a higher abundance of at least one of the miRNAs, isomiRs, precursor miRNAs, or transfer RNA fragments whose nucleotide sequence is represented by any one of SEQ ID NOs: 1 to 20 than that of healthy subjects or a lower abundance of at least one of the miRNAs, isomiRs, precursor miRNAs, or non-coding RNA fragments (MiscRNAs) whose nucleotide sequence is represented by any one of SEQ ID NOs: 21 to 38 than that of healthy subjects indicates a higher likelihood of having pancreatic cancer.
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