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公开(公告)号：EP3578587A1
公开(公告)日：2019-12-11
申请号：EP18186250.9
申请日：2018-07-30
发明人： Jeon, You-Jin , Ryu, BoMi
IPC分类号： C08G65/44 , A61P3/10 , A61K31/09 , C07C43/295
摘要： Disclosed herein are hexadecaphlorethol (HdP), which is a novel compound isolated from Ishige okamurae, and the use thereof in anti-diabetic treatment and exercise performance improvement. The novel compound HdP has the activity of inhibiting α-glucosidase, inducing glucose uptake into differentiated myoblast C2C12 cells, reducing blood glucose levels in zebrafish which have reduced insulin secretion through treatment with alloxan, increasing an intracellular level of calcium ions necessary for muscle contraction and exercise performance in zebrafish, and inducing uptake of glucose, an energy source necessary for muscle contraction, into cells.
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公开(公告)号：EP3482752B1
公开(公告)日：2020-03-25
申请号：EP18205072.4
申请日：2018-11-08
申请人： Gachon University of Industry-Academic Cooperation Foundation , Jeju National University Industry-Academic Cooperation Foundation
发明人： BYUN, Kyunghee , SON, Myeongjoo , LEE, Hye Sun , OH, Seyeon , CHOI, Junwon , JEON, You-Jin
IPC分类号： A61K31/05 , A61K31/357 , A61K36/03 , A61P9/10
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公开(公告)号：EP4414752A1
公开(公告)日：2024-08-14
申请号：EP22878669.5
申请日：2022-07-04
发明人： JEONG, Manhee
摘要： The present invention provides a neutron-shielding coded aperture having a boron polyethylene (PE) mask, which is attached to the front end of a tungsten mask pattern of a coded aperture and has the same pattern. In order to alleviate a neutron-shielding problem, a material, in which high-density polyethylene (HDPE) having excellent neutron-shielding ability is mixed with boron, is attached to the front end of a conventional coded aperture so as to block both gamma rays and neutrons.
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4.发明公开
公开(公告)号：EP3581191A1
公开(公告)日：2019-12-18
申请号：EP19180523.3
申请日：2019-06-17
发明人： Kim, Gi-Young , Choi, Yung Hyun , Park, Eui Kyun , Lee, Bae Jin , Jeon, You-Jin
IPC分类号： A61K35/618 , A61K36/02 , A61K36/03 , A61K36/04 , A61K36/05 , A61K31/185 , A61K31/197 , A61K31/198 , A61K31/737 , A61P19/08 , A61P19/10
摘要： The present invention relates to a composition for improving bone health, including a functional fermented material using oysters, and the composition includes a fermented extract extracted from a fermented material of oysters and seaweed, which is obtained by fermenting oysters and seaweed, and the fermented extract may promote bone formation by suppressing the activity of osteoclasts and promoting the activity of osteoblasts.
According to the present invention, it is possible to provide a composition for improving bone health, containing large amounts of taurine and vitamins and containing natural gamma-aminobutyric acid (GABA) and seaweed oligosaccharides from seaweeds using oysters.
Further, it is possible to provide a composition for improving bone health, including a functional fermented material using oysters which is excellent in effects of preventing and suppressing the occurrence of osteoporosis.-
公开(公告)号：EP3392316B1
公开(公告)日：2019-08-07
申请号：EP18176146.1
申请日：2014-11-04
发明人： KIM, Sang-Jae , KARTHIKEYAN, K
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6.发明公开
公开(公告)号：EP3392316A1
公开(公告)日：2018-10-24
申请号：EP18176146.1
申请日：2014-11-04
发明人： KIM, Sang-Jae , KARTHIKEYAN, K
CPC分类号： C09D5/1618 , C08K2003/221 , C08K2003/2296 , C09D7/61 , C09D7/67 , C09D167/08 , C08K3/22 , C08K3/01
摘要： Provided is a paint composition and, more specifically, to a non-toxic paint composition containing molybdenum oxide (MoO 3 ) nanoplates, and to a method for preparing the same. Specifically, the paint composition according to the present invention is economical and rapidly dried due to a high solid content as compared with the conventional paints; is environment-friendly, and exhibits excellent corrosion resistance in an acidic and high-salt solution due to the absence of toxic materials such as a chromate or biocide; and has excellent effects of inhibiting the growth of bacteria strains ( Escherichia coli , Staphylococcus aureus , and Pseudomonas aeruginosa ) and suppressing the adhesion of marine organisms, and thus can be effectively used as a substitute for paints used in general steel structures and ships or marine steel structures.
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7.发明公开
公开(公告)号：EP3321379A1
公开(公告)日：2018-05-16
申请号：EP17200547.2
申请日：2017-11-08
申请人： Republic of Korea , Korea Research Institute of Bioscience and Biotechnology , Jeju National University Industry-Academic Cooperation Foundation
IPC分类号： C12Q1/6888
摘要： The present invention relates to a genetic marker for determining meat quality traits of pigs and a use thereof, and specifically, a genetic marker for determining meat quality traits of pigs, comprising a polynucleotide consisting of 5 to 300 consecutive nucleotides comprising the nucleotides from the 1524 th to the 1527 th positions in the polynucleotide of SEQ ID NO: 1, or a polynucleotide complementary thereto, a composition for determining meat quality traits of pigs comprising an agent capable of detecting the genetic marker, a composition for determining Korean native pigs, a kit, a microarray, a method for determining meat quality traits of pigs, and a method for determining meat quality traits of Korean native pigs.
The genetic marker of the present invention is a specific marker for determining the meat quality traits of pigs, and thus the marker can be used not only as a means for the objective evaluation of meat quality traits of pigs that cannot be determined by the naked eye but also as a means for distinguishing between foreign pigs and Korean native pigs, and is thereby capable of contributing to the establishment of distribution order of pork meat.摘要翻译： 本发明涉及用于确定猪肉品质性状的遗传标记及其用途，具体地涉及用于确定猪肉品质性状的遗传标记，其包含由5至300个连续核苷酸组成的多核苷酸，所述连续核苷酸包含来自第1524位 SEQ ID NO：1的多核苷酸中的第1527位或与其互补的多核苷酸，包含能够检测遗传标记的试剂的猪肉品质性状测定组合物，用于测定韩国本土猪的组合物，试剂盒， 微阵列，测定猪肉品质性状的方法，以及测定韩国本土猪肉品质性状的方法。 本发明的遗传标记是用于确定猪肉品质性状的特异性标记，因此该标记不仅可以用作客观评价猪肉肉质性状的手段，肉品肉质性状不能用肉眼确定 还可以作为区分外国猪和韩国本土猪的手段，从而有助于建立猪肉分销秩序。
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8.发明公开
公开(公告)号：EP4295772A1
公开(公告)日：2023-12-27
申请号：EP22771831.9
申请日：2022-03-21
申请人： JEJU NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION , Jeju National University Hospital
摘要： The present disclosure relates to a method for providing information necessary for assessing severity of coronary artery stenosis, the method includes: administering a contrast agent to a coronary artery; capturing an angiographic image; setting a suspected stenosis area where stenosis is suspected and a proximal area where blood passes before the suspected stenosis area within region of captured image for observing the coronary artery stenosis based on the captured angiographic image; fixing position of the coronary artery where the contrast agent is administered by image processing; and deriving a blood flow velocity ratio, which is a relative ratio of blood flow in the proximal area and the suspected stenosis area, based on time when brightness changes in the proximal area and the suspected stenosis area of the captured image.
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公开(公告)号：EP4163680A1
公开(公告)日：2023-04-12
申请号：EP21838017.8
申请日：2021-02-26
发明人： JUNG, Man-hui , BU, Ji-hwan
摘要： Disclosed is a coded-aperture-based dual particle image fusion apparatus that simultaneously fuses a real-time site image of a radiation source and a reaction image of gamma rays and neutrons to perform nuclide discrimination through the position of radiation, dose per second, and spectrum information, to provide numerical information of dose, and to visualize position information of gamma rays and neutrons through GPS information, whereby it is possible to secure worker safety, and that has a compact size so as to be easily carried, whereby it is possible to create a radiation distribution map based on location movement.
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公开(公告)号：EP3482752A1
公开(公告)日：2019-05-15
申请号：EP18205072.4
申请日：2018-11-08
申请人： Gachon University of Industry-Academic Cooperation Foundation , Jeju National University Industry-Academic Cooperation Foundation
发明人： BYUN, Kyunghee , SON, Myeongjoo , LEE, Hye Sun , OH, Seyeon , CHOI, Junwon , JEON, You-Jin
IPC分类号： A61K31/05 , A61K31/357 , A61K36/03 , A61P9/10
摘要： The present invention relates to an Ecklonia cava extract, a preparation method thereof and a pharmaceutical composition for preventing or treating vascular diseases comprising the same as an active ingredient. The Ecklonia cava extract of the present invention was confirmed to have a medicinal effect on those factors involved in causing vascular diseases by the cell level experiments and the disease induced animal model experiments. Therefore, the Ecklonia cava extract of the present invention can be effectively used as an active ingredient of a pharmaceutical composition and a health functional food composition for the prevention, improvement or treatment of vascular diseases.
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