公开(公告)号：EP4205750A1

公开(公告)日：2023-07-05

申请号：EP23157391.6

申请日：2017-01-11

Applicant: National University Corporation Tokyo Medical and Dental University

Inventor： NISHIMURA, Emi ,  MATSUMURA, Hiroyuki

IPC: A61K36/04 ,  A61K36/05 ,  A61K36/14 ,  A61K36/18 ,  A61K36/185 ,  A61K36/23 ,  A61K36/28 ,  A61K36/30 ,  A61K36/424 ,  A61K36/47 ,  A61K36/48 ,  A61K36/488 ,  A61K36/489 ,  A61K36/53 ,  A61P17/14 ,  A61K31/12 ,  A61K31/137 ,  A61K31/437 ,  A61K31/519 ,  A61K31/5415

Abstract: The present invention provides novel compositions for suppressing or improving hair loss, and compositions for suppressing or improving graying. More specifically, it provides agents that stabilize type XVII collagen expression, preferably agents that suppress the degradation of type XVII collagen by ELANE inhibitors and such, and compositions comprising a DNA repair-promoting agent or a DNA damage-suppressing agent as an active ingredient. Advantageous suppressive effects of hair loss and graying can be obtained when a composition comprising as an active ingredient a suppressive agent of type XVII collagen degradation such as an ELANE inhibitor is administered to a mammal. For the ELANE inhibitors, suppressive agents of type XVII collagen degradation and DNA repair-promoting agents, low-molecular compounds, polypeptides, proteins, antibodies, or nucleic acid medicine such as antisense oligos or siRNAs may be used. A method of screening for effective substances for suppression of hair loss and graying is also provided.

公开(公告)号：EP3902518A1

公开(公告)日：2021-11-03

申请号：EP19835309.6

申请日：2019-12-30

Applicant: Laboratoires Expanscience

Inventor： LECLERE-BIENFAIT, Sophie ,  BREDIF, Stéphanie

IPC: A61K8/9722 ,  A61K36/05 ,  A61P17/00 ,  A61P37/08 ,  A61K8/9706

公开(公告)号：EP3870198A1

公开(公告)日：2021-09-01

申请号：EP19801216.3

申请日：2019-10-22

Applicant: Amadeite

Inventor： ASEHNOUNE, Karim ,  JACQUELINE, Cédric ,  BOURAS, Marwan ,  ROQUILLY, Antoine ,  NYVALL-COLLÉN, Pi ,  DEMAIS, Hervé ,  BALUSSON, Hervé

IPC: A61K36/05 ,  A61P37/04 ,  A61P31/00

公开(公告)号：EP3831399A1

公开(公告)日：2021-06-09

申请号：EP19844221.2

申请日：2019-07-25

Applicant: DENSO CORPORATION ,  Chubu University Educational Foundation

Inventor： ASANO Mana ,  KUNO Hitoshi ,  ATSUMI Kinya ,  HAYASHI Kyoko ,  KAWAHARA Tosihio ,  KOMATSU Satoko

IPC: A61K36/05 ,  A01N43/16 ,  A01N65/03 ,  A01P1/00 ,  A23K10/16 ,  A23L33/105 ,  A23L33/12 ,  A61K31/7032 ,  A61K35/68 ,  A61K35/748 ,  A61K36/02 ,  A61P31/14

Abstract: An object of the invention is to provide a novel means effective for treatment of infectious diseases due to norovirus or prevention of spreading of infectious diseases due to norovirus. An anti-norovirus agent containing a unicellular alga-derived substance as an effective ingredient is provided.

公开(公告)号：EP2934505B1

公开(公告)日：2021-05-19

申请号：EP13867433.8

申请日：2013-12-18

Inventor： WAIBEL, Brian J. ,  SCHONEMANN, Hans ,  KRUKONIS, Val ,  KAGAN, Michael

IPC: A61K31/202 ,  A61P9/00 ,  A61P25/00 ,  A61K36/05 ,  A61K31/555 ,  A61K31/232 ,  A61K31/683 ,  A61K31/7032 ,  A61K31/20 ,  A61K31/201 ,  A61K31/685 ,  A61K45/06 ,  A23D9/013 ,  C11B1/10 ,  C11B3/00 ,  C11B7/00

公开(公告)号：EP3710028A1

公开(公告)日：2020-09-23

申请号：EP18815792.9

申请日：2018-11-13

Applicant: University of Greenwich

Inventor： HARVEY, Patricia Janine ,  XU, Yanan

IPC: A61K36/05 ,  C12N1/12

公开(公告)号：EP3551292A1

公开(公告)日：2019-10-16

申请号：EP17878515.0

申请日：2017-12-07

Applicant: Balchem Corporation

Inventor： BORTZ, Jonathan David

IPC: A61P25/00 ,  A61P9/00 ,  A61K36/05 ,  A61K31/202

公开(公告)号：EP3518949A1

公开(公告)日：2019-08-07

申请号：EP17794793.4

申请日：2017-09-28

Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.

Inventor： GARTI, Nissim ,  GARTI LEVI, Sharon ,  EDRI, Rotem

IPC: A61K36/05 ,  A61K47/00

公开(公告)号：EP3459367A1

公开(公告)日：2019-03-27

申请号：EP17810350.3

申请日：2017-06-07

Applicant: AstaReal Co., Ltd.

Inventor： TOMINAGA Kumi ,  HONGO Nobuko ,  FUJISHITA Mayuko

IPC: A23L33/10 ,  A23L33/115 ,  A23L33/15 ,  A23L33/155 ,  A61K31/122 ,  A61K31/355 ,  A61K36/05 ,  A61K36/63 ,  A61P25/00 ,  A61P25/18 ,  A61P25/20 ,  A61P25/24 ,  A61P25/28 ,  A61P43/00

Abstract: Provided are a food-and-drink composition, food-and-drink, and so on containing astaxanthin and/or astaxanthin-containing extract as an active ingredient. The food-and-drink composition, food-and-drink, and so on containing astaxanthin and/or astaxanthin-containing extract as an active ingredient exert actions and effects to improve dull-headedness, improve decreased concentration, improve decreased motivation, improve depressed mood, resolve frustration, reduce feeling of body heaviness, and improve decreased vigor and/or activity, in a healthy human male or female having a sense of fatigue, in particular, a sense of fatigue caused by a mental load or a sense of fatigue caused by a mental load and a physical load.

公开(公告)号：EP3403673A1

公开(公告)日：2018-11-21

申请号：EP17738422.9

申请日：2017-01-11

Applicant: National University Corporation Tokyo Medical and Dental University

Inventor： NISHIMURA, Emi ,  MATSUMURA, Hiroyuki

IPC: A61K45/00 ,  A61K8/97 ,  A61K31/222 ,  A61K31/506 ,  A61K31/7088 ,  A61K31/713 ,  A61K36/04 ,  A61K36/05 ,  A61K36/14 ,  A61K36/18 ,  A61K36/185 ,  A61K36/23 ,  A61K36/28 ,  A61K36/30 ,  A61K36/424 ,  A61K36/47 ,  A61K36/48 ,  A61K36/488 ,  A61K36/489 ,  A61K36/53

CPC classification number: A61K31/713 ,  A61K8/97 ,  A61K31/05 ,  A61K31/16 ,  A61K31/222 ,  A61K31/355 ,  A61K31/375 ,  A61K31/381 ,  A61K31/506 ,  A61K31/7048 ,  A61K31/7088 ,  A61K36/04 ,  A61K36/05 ,  A61K36/14 ,  A61K36/18 ,  A61K36/185 ,  A61K36/23 ,  A61K36/28 ,  A61K36/30 ,  A61K36/424 ,  A61K36/47 ,  A61K36/48 ,  A61K36/488 ,  A61K36/489 ,  A61K36/53 ,  A61K36/54 ,  A61K36/60 ,  A61K36/718 ,  A61K36/738 ,  A61K36/74 ,  A61K36/82 ,  A61K38/55 ,  A61K39/395 ,  A61K45/00 ,  A61K48/00 ,  A61P17/14 ,  A61Q5/00 ,  A61Q7/00 ,  C12Q1/37

Abstract: The present invention provides novel compositions for suppressing or improving hair loss, and compositions for suppressing or improving graying. More specifically, it provides agents that stabilize type XVII collagen expression, preferably agents that suppress the degradation of type XVII collagen by ELANE inhibitors and such, and compositions comprising a DNA repair-promoting agent or a DNA damage-suppressing agent as an active ingredient. Advantageous suppressive effects of hair loss and graying can be obtained when a composition comprising as an active ingredient a suppressive agent of type XVII collagen degradation such as an ELANE inhibitor is administered to a mammal. For the ELANE inhibitors, suppressive agents of type XVII collagen degradation and DNA repair-promoting agents, low-molecular compounds, polypeptides, proteins, antibodies, or nucleic acid medicine such as antisense oligos or siRNAs may be used. A method of screening for effective substances for suppression of hair loss and graying is also provided.