公开(公告)号：EP0671922B1

公开(公告)日：2000-05-10

申请号：EP94900605.0

申请日：1993-11-10

申请人： PURDUE RESEARCH FOUNDATION ,  METHODIST HOSPITAL OF INDIANA, INC. ,  KNAPP, Peter M., Jr.

发明人： KNAPP, Peter, M., Jr. ,  BADYLAK, Stephen, F. ,  HILES, Michael ,  VOYTIK, Sherry ,  DEMETER, Robert, J.

IPC分类号： A61K35/38 ,  A61F2/02 ,  A61F2/30 ,  A61F2/38 ,  A61F2/44

CPC分类号： A61L27/3695 ,  A61F2/28 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30677 ,  A61F2210/0004 ,  A61K35/38 ,  A61L27/3629 ,  A61L27/3645 ,  A61L27/365 ,  A61L27/367 ,  A61L27/3683 ,  A61L27/3691 ,  A61L2400/06

摘要： A fluidized, injectable tissue graft composition is described. The composition comprises comminuted intestinal submucosa or protease-digested intestinal submucosa. Methods for the preparation and use of injectable tissue graft compositions are described. In preferred embodiments the tissue graft material is prepared from the intestinal submucosa comprising the tunica submucosa, the muscularis mucosa and the stratum compactum of a segment of intestinal tissue of a warm-blooded vertebrate. Effective amounts of the fluidized graft compositions can be injected to promote repair tissue defects by inducing formation of endogenous tissues.

公开(公告)号：EP0671922A4

公开(公告)日：1996-08-21

申请号：EP94900605

申请日：1993-11-10

申请人： PURDUE RESEARCH FOUNDATION ,  METHODIST HOSPITAL INDIANA ,  KNAPP PETER M JR

发明人： BADYLAK STEPHEN F ,  HILES MICHAEL ,  WOYTIK SHERRY ,  DEMETER ROBERT J ,  KNAPP PETER M JR

IPC分类号： A61F2/02 ,  A61F2/28 ,  A61F2/30 ,  A61F2/38 ,  A61F2/44 ,  A61K35/38 ,  A61L27/00 ,  A61L27/36 ,  A61P3/00 ,  A61P43/00

CPC分类号： A61L27/3695 ,  A61F2/28 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30677 ,  A61F2210/0004 ,  A61K35/38 ,  A61L27/3629 ,  A61L27/3645 ,  A61L27/365 ,  A61L27/367 ,  A61L27/3683 ,  A61L27/3691 ,  A61L2400/06

摘要： A fluidized, injectable tissue graft composition is described. The composition comprises comminuted intestinal submucosa or protease-digested intestinal submucosa. Methods for the preparation and use of injectable tissue graft compositions are described. In preferred embodiments the tissue graft material is prepared from the intestinal submucosa comprising the tunica submucosa, the muscularis mucosa and the stratum compactum of a segment of intestinal tissue of a warm-blooded vertebrate. Effective amounts of the fluidized graft compositions can be injected to promote repair tissue defects by inducing formation of endogenous tissues.

公开(公告)号：EP0671922A1

公开(公告)日：1995-09-20

申请号：EP94900605.0

申请日：1993-11-10

申请人： PURDUE RESEARCH FOUNDATION ,  METHODIST HOSPITAL OF INDIANA, INC. ,  KNAPP, Peter M., Jr.

发明人： KNAPP, Peter, M., Jr. ,  BADYLAK, Stephen, F. ,  HILES, Michael ,  VOYTIK, Sherry ,  DEMETER, Robert, J.

IPC分类号： A61F2 ,  A61K35 ,  A61L27 ,  A61P3 ,  A61P43

CPC分类号： A61L27/3695 ,  A61F2/28 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30677 ,  A61F2210/0004 ,  A61K35/38 ,  A61L27/3629 ,  A61L27/3645 ,  A61L27/365 ,  A61L27/367 ,  A61L27/3683 ,  A61L27/3691 ,  A61L2400/06

摘要： A fluidized, injectable tissue graft composition is described. The composition comprises comminuted intestinal submucosa or protease-digested intestinal submucosa. Methods for the preparation and use of injectable tissue graft compositions are described. In preferred embodiments the tissue graft material is prepared from the intestinal submucosa comprising the tunica submucosa, the muscularis mucosa and the stratum compactum of a segment of intestinal tissue of a warm-blooded vertebrate. Effective amounts of the fluidized graft compositions can be injected to promote repair tissue defects by inducing formation of endogenous tissues.