摘要:
The invention relates to a combination comprising an antineoplastic agent, e.g. an antimetabolite antineoplastic agent and a serotonin receptor (HTR) modulator, e.g. a HTR antagonist. In addition the invention relates to a pharmaceutical composition comprising a combination of the invention and a pharmaceutically acceptable excipient. The invention also relates to the combination and pharmaceutical composition according to the invention for use in medicine, particularly for use in the prevention and/or treatment of a hematological malignancy.
摘要:
The invention relates to a method for generating a spectrum extending from the infrared range to the ultraviolet range, consisting of injecting, into a microstructured optical fiber, a pumped laser beam having a wavelength in the infrared range, characterized in that the method includes the following steps: generating, in the fiber, a first four-wave mixing or a primary mixing centered on the wavelength of said laser beam; generating, in the fiber, a second four-wave mixing centered on one (32) of the rays (32, 34) from the first four-wave mixing or secondary pump ray; and widening the spectrum about one (36) of the rays from the second four-wave mixing.
摘要:
The present invention relates to new compounds of formula (I):
as modulators of serotonin receptor 1B (5-HTR 1B ) also known as 5-hydroxytryptamine receptor 1B (5-HT 1B ). The compounds are of potential utility in the treatment of diseases and conditions mediated by serotonin receptor type 1B (5-HTR 1B ), such as cancer, including blood cancer and solid tumors, respiratory diseases and hepatic disorders.
摘要:
The subject of the invention is a supercontinuum source capable of emitting waves between the infrared range and the ultraviolet range, comprising a pulsed laser source (12) capable of generating a laser beam and a non-linear microstructured optical fibre (14) capable of receiving said laser beam, in such a way that the supercontinuum source is capable of generating a beam (F') over a pulse duration (T'), characterized in that the supercontinuum source includes means for varying said pulse duration.