-
1.发明公开DPA-ENRICHED COMPOSITIONS OF OMEGA-3 POLYUNSATURATED FATTY ACIDS IN FREE ACID FORM 有权DPA富含不饱和多OMEGA-3脂肪酸的形式化合物中的自由
公开(公告)号：EP2800563A1
公开(公告)日：2014-11-12
申请号：EP13733671.5
申请日：2013-01-04
发明人： MAINES, Timothy, J. , MACHIELSE, Bernardus N M , MEHTA, Bharat M. , WISLER, Gerald , DAVIDSON, Michael , WOOD, Peter Ralph
CPC分类号： A61K31/202 , A61K9/4825 , A61K31/366 , A61K45/06 , A61K2300/00
摘要： DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form, therapeutic methods for their use, and processes for refining the compositions from fish oil are presented.
摘要翻译： DPA-富集的游离酸形式的多不饱和脂肪酸的药物组合物，治疗方法对于它们的用途，和流程用于精炼鱼油的组合物呈现。
-
2.发明公开METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING ATTENTION DEFICIT HYPERACTIVITY DISORDER 审中-公开方法和组合物治疗或预防注意力缺失症
公开(公告)号：EP2806736A4
公开(公告)日：2015-10-14
申请号：EP12841851
申请日：2012-10-19
IPC分类号： A01N37/00
CPC分类号： G01N33/92 , A23L33/12 , A61K9/006 , A61K31/202 , A61K31/232 , A61K45/06 , C12Q1/26 , C12Q1/6883 , C12Q2600/156 , G01N2800/305 , G01N2800/50 , Y10T436/143333 , A61K2300/00
-
3.发明公开DPA-ENRICHED COMPOSITIONS OF OMEGA-3 POLYUNSATURATED FATTY ACIDS IN FREE ACID FORM 有权DPA富含不饱和多OMEGA-3脂肪酸的形式化合物中的自由
公开(公告)号：EP2800563A4
公开(公告)日：2015-06-17
申请号：EP13733671
申请日：2013-01-04
发明人： MAINES TIMOTHY J , MACHIELSE BERNARDUS N M , MEHTA BHARAT M , WISLER GERALD , DAVIDSON MICHAEL , WOOD PETER RALPH
CPC分类号： A61K31/202 , A61K9/4825 , A61K31/366 , A61K45/06 , A61K2300/00
摘要： Methods for making DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form are presented.
-
公开(公告)号：EP2800563B1
公开(公告)日：2018-07-11
申请号：EP13733671.5
申请日：2013-01-04
发明人： MAINES, Timothy, J. , MACHIELSE, Bernardus N M , MEHTA, Bharat M. , WISLER, Gerald , DAVIDSON, Michael , WOOD, Peter Ralph
IPC分类号： A61K31/19 , A61K31/202 , A61K31/366 , A61K45/06 , A61K9/48 , A61P9/00
CPC分类号： A61K31/202 , A61K9/4825 , A61K31/366 , A61K45/06 , A61K2300/00
摘要： Methods for making DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form are presented.
-
5.发明公开COMPOSITIONS OF STATINS AND OMEGA-3 FATTY ACIDS 审中-公开OMUSA-3-FETTSÄUREN的ZUSAMMENSETZUNGEN AUS STATINEN
公开(公告)号：EP2846779A4
公开(公告)日：2015-12-16
申请号：EP13787637
申请日：2013-05-07
IPC分类号： A61K9/42 , A61K31/202 , A61K31/22 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/47 , A61K31/55 , A61P3/06
CPC分类号： A61K47/12 , A61K9/4825 , A61K9/4891 , A61K31/202 , A61K31/22 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/47 , A61K31/505 , A61K31/55 , A61K2300/00
摘要： The present disclosure provides pharmaceutical compositions of statins and polyunsaturated fatty acids (PUFAs), in which the statins are dissolved in the PUFAs, the PUFA species being present substantially in the free acid form. Also provided are oral unit dosage forms of the disclosed pharmaceutical compositions and methods of treating blood lipid disorders using the compositions and oral unit dosage forms.
摘要翻译： 本公开提供了他汀类和多不饱和脂肪酸（PUFA）的药物组合物，其中他汀类药物溶解在PUFA中，PUFA物质基本上以游离酸形式存在。 还提供了所公开的药物组合物的口服单位剂量形式和使用组合物和口服单位剂型治疗血脂紊乱的方法。
-
6.发明公开METHODS AND COMPOSITIONS FOR TREATING, REVERSING, INHIBITING OR PREVENTING RESISTANCE TO ANTIPLATELET THERAPY 审中-公开FOR THE方法和组合物，反转，抑制或抗性的预防到治疗THROMBOZYTENGEMMENDEN
公开(公告)号：EP2755646A1
公开(公告)日：2014-07-23
申请号：EP12832680.8
申请日：2012-09-14
IPC分类号： A61K31/20
CPC分类号： A61K31/202 , A61K9/4816 , A61K31/366 , A61K31/4365 , A61K31/616 , A61K45/06 , A61K2300/00
摘要： Methods of identifying subjects who are resistant to antiplatelet therapy, such as therapy with clopidogrel, are presented. The methods comprise determining is whether the subject is an efficient converter of medium chain polyunsaturated fatty acids to long-chain polyunsaturated fatty acids. Also provided are methods of treating resistance to antiplatelet therapy in subjects who are efficient converters of medium chain polyunsaturated fatty acids to long-chain polyunsaturated fatty acids, comprising adjunctively administering to the subject an effective amount of a composition comprising omega-3 long chain polyunsaturated fatty acids. Improved methods of antiplatelet therapy are provided, wherein the improvement comprises adjunctive administration of a composition comprising omega-3 long chain polyunsaturated fatty acids in free acid form. Dosage forms comprising at least one antiplatelet agent and compositions comprising omega-3 long chain polyunsaturated fatty acids, including compositions comprising omega-3 long chain polyunsaturated fatty acids in free acid form, are provided.
-
7.发明公开
公开(公告)号：EP3348262A1
公开(公告)日：2018-07-18
申请号：EP18158463.2
申请日：2013-01-04
发明人： MAINES, Timothy, J , MACHIELSE, Bernardus N M , MEHTA, Bharat M , WISLER, Gerald , DAVIDSON, Michael , WOOD, Peter Ralph
IPC分类号： A61K31/202 , A61K31/366 , A61K45/06 , A61P9/00
CPC分类号： A61K31/202 , A61K9/4825 , A61K31/366 , A61K45/06 , A61K2300/00
摘要： Methods for making DPA-enriched pharmaceutical compositions of polyunsaturated fatty acids in free acid form are presented.
-
公开(公告)号：EP3261622A1
公开(公告)日：2018-01-03
申请号：EP16756086.1
申请日：2016-02-19
发明人： KUBOTA, Hironori , ROGEAU, Etienne Thierry Charles , AMEMIYA, Toru , MEISSONNIER, Julien Georges , HOLMÉN, Anders Gillis , RADEVIK, Andreas , CARLSSON, Hans , SCHANTZ, Bengt Staffan
IPC分类号： A61K9/14
CPC分类号： A61K9/4891 , A61K9/4808 , A61K9/4825 , A61K9/4833 , A61K9/5026 , A61K9/5047 , A61K9/5057 , A61K31/135 , A61K31/202 , A61K2300/00 , A61P1/16 , A61P3/06 , A61P11/00
摘要： Capsular dosage forms containing polyunsaturated fatty acid (PUFA) compositions are provided herein. In certain embodiments, unit dosage forms comprising a plurality of millicapsules containing a PUFA composition therein are provided as well as their methods of use and manufacture. In certain embodiments, capsular dosage forms are provided herein that include a unit dosage form comprising a plurality of millicapsules containing a polyunsaturated free fatty acid substantially in free acid form. In some embodiments, the PUFA composition is Epanova®.
-
9.发明公开METHODS AND COMPOSITIONS FOR TREATING, REVERSING, INHIBITING OR PREVENTING RESISTANCE TO ANTIPLATELET THERAPY 审中-公开FOR THE方法和组合物，反转，抑制或抗性的预防到治疗THROMBOZYTENGEMMENDEN
公开(公告)号：EP2755646A4
公开(公告)日：2015-06-10
申请号：EP12832680
申请日：2012-09-14
IPC分类号： A61K31/20 , A61K9/48 , A61K31/202 , A61K31/366 , A61K31/4365 , A61K31/616 , A61K45/06 , A61P7/02
CPC分类号： A61K31/202 , A61K9/4816 , A61K31/366 , A61K31/4365 , A61K31/616 , A61K45/06 , A61K2300/00
-
公开(公告)号：EP2846779A1
公开(公告)日：2015-03-18
申请号：EP13787637.1
申请日：2013-05-07
IPC分类号： A61K9/42
CPC分类号： A61K47/12 , A61K9/4825 , A61K9/4891 , A61K31/202 , A61K31/22 , A61K31/366 , A61K31/40 , A61K31/405 , A61K31/47 , A61K31/505 , A61K31/55 , A61K2300/00
摘要： The present disclosure provides pharmaceutical compositions of statins and polyunsaturated fatty acids (PUFAs), in which the statins are dissolved in the PUFAs, the PUFA species being present substantially in the free acid form. Also provided are oral unit dosage forms of the disclosed pharmaceutical compositions and methods of treating blood lipid disorders using the compositions and oral unit dosage forms.
-
-
-
-
-
-
-
-
-
搜索结果
11 条记录 (耗时 0.015 秒)
