中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

76 records (took 0.02 seconds)

    IMPROVED IMAGING METHOD AND APPARATUS
    1.
    发明授权
    IMPROVED IMAGING METHOD AND APPARATUS 失效
    其实现图的方法和装置

    公开(公告)号：EP0787288B1

    公开(公告)日：2009-03-04

    申请号：EP95933559.7

    申请日：1995-10-18

    Applicant: Packard Instrument Company, Inc.

    Inventor： ANSORGE, Richard, Eric ,  RUSHBROOKE, John, Gordon ,  HOOPER, Claire, Elizabeth ,  NEALE, William, Wray

    IPC: G01N21/64 ,  C12M1/34

    CPC classification number: G01N21/6456 ,  G01N2021/6441

    Abstract: A method of detecting the presence and position of labelled material in a sample in which the labelled material either gives of light or can be stimulated to do so. The sample is imaged onto an image intensified CCD camera which is scanned following each exposure. Measurements are performed on the data signals so obtained, to identify clusters of data values from adjacent regions of the CCD array caused by light emitted by the image intensifier incident on those regions. The measured signal values are compared with at least one threshold so as to distinguish clusters resulting from light emitting regions of labelled material from the remainder of the sample and the centroid of each light produced cluster of data values is computed with reference to the camera array, and a signal value corresponding to the centroid coordinates is stored in a memory together with the centroid coordinates of any other light produced clusters identified during the same interrogation. The coordinates from each of a succession of interrogations of the same sample may be stored in an accumulation store to enable a list of the recorded light emissions and/or display of the events, to be produced by reading out the store. Apparatus for performing this method is also described.

    LUMINESCENCE IMAGER
    3.
    发明授权
    LUMINESCENCE IMAGER 有权
    发射装置PICTURE

    公开(公告)号：EP1348120B1

    公开(公告)日：2006-03-08

    申请号：EP01272703.8

    申请日：2001-12-18

    Applicant: Packard Instrument Company, Inc.

    Inventor： RUSHBROOKE, John, Gordon ,  HOOPER, Claire, Elizabeth

    IPC: G01N21/64

    CPC classification number: G01N21/6452 ,  G01N21/6456 ,  G01N21/76 ,  G01N2021/6484 ,  G01N2201/0826 ,  G01N2201/0833

    Abstract: A fibre optic epi-fluorescence imaging system in which the optical fibres are rearranged so that the system can be used for measuring luminescence samples. The system comprises at least two optical fibres (32, 46) or bundles of fibres which lead to a CCD camera (74), the fibres or bundles of fibres from all samples being arranged in two sets, a first set which are formed from a non-fluorescing material and a second set which are formed from a material which may fluoresce but enables the fibres formed therefrom to have a higher numerical aperature than those of the first set.

    Microvolume liquid handling system
    5.
    发明公开
    Microvolume liquid handling system 失效
    Vorrichtung zur Handhabung vonMikroflüssigkeitsmengen

    公开(公告)号：EP1512975A2

    公开(公告)日：2005-03-09

    申请号：EP04028043.0

    申请日：1998-04-08

    Applicant: Packard Instrument Company, Inc.

    Inventor： Pelc, Richard E. ,  Chibucos, Nicholas S. ,  Papen, Roeland F. ,  Mayer, Wilhelm

    IPC: G01N35/10 ,  B01L3/02

    CPC classification number: B01L3/0268 ,  B01J2219/00378 ,  B01L3/5085 ,  B01L2200/025 ,  B01L2200/146 ,  B01L2300/0838 ,  B01L2400/0439 ,  B01L2400/0487 ,  C40B60/14

    Abstract: A system for dispensing precise quantities of a transfer liquid (24) is described. The system comprises an enclosed space (214, 234, 235) containing a fluid column, the fluid column including the transfer liquid (24) and a system liquid (20). The enclosed space has an outlet (36) and the column is arranged with the transfer liquid (24) being adjacent to the outlet (63) and the system liquid (20) being distant to the outlet (63). Means (218) are provided for supplying the system liquid (20) into the fluid column (24, 20); and means are present for providing the transfer liquid (24) into the enclosed space (214, 234, 236). The system further includes means (212) for dispensing a quantity of the transfer liquid (24) as at least one droplet out of the outlet (63) without introducing any fluid into the enclosed space (214, 234, 236) during dispensing, means (244) for sensing pressure change in the enclosed space resulting from the volume of the transfer liquid being dispensed and means (224) for converting the pressure change to a volume of the transfer liquid (24) dispensed by the dispensing means (212), wherein ejection of individual drops of the transfer liquid (24) can be detected by the means for sensing pressure change (244).

    Abstract translation: 描述了用于分配精确量的转移液体（24）的系统。 所述系统包括容纳流体柱的封闭空间（214,234,235），所述流体柱包括所述转移液体（24）和系统液体（20）。 所述封闭空间具有出口（36），并且所述柱布置成与所述出口（63）相邻的所述转移液体（24）和所述系统液体（20）远离所述出口（63）。 提供装置（218）用于将系统液体（20）供应到流体柱（24,20）中; 并且存在用于将转移液体（24）提供到封闭空间（214,234,236）中的装置。 该系统还包括用于在分配期间将一定数量的转移液体（24）作为至少一个液滴排出出口（63）而不将任何流体引入封闭空间（214,234,236）中的装置（212） （244），用于感测由所分配的转印液体的体积导致的封闭空间中的压力变化;以及用于将压力变化转换成由分配装置（212）分配的转印液体的体积的装置（224） 其中可以通过用于感测压力变化的装置（244）来检测转移液体（24）的单个液滴的喷射。

    METHOD AND APPARATUS FOR DISPENSING MICRODROPLETS
    8.
    发明公开
    METHOD AND APPARATUS FOR DISPENSING MICRODROPLETS 有权
    方法和装置DROP微分配

    公开(公告)号：EP1356252A2

    公开(公告)日：2003-10-29

    申请号：EP02703210.1

    申请日：2002-01-23

    Applicant: Packard Instrument Company, Inc.

    Inventor： ZWEIFEL, Ronald, A. ,  HAHN, Christopher, M.

    IPC: G01F1/00

    CPC classification number: B01L3/0268 ,  B01L3/0262 ,  G01N35/1011 ,  G01N35/1016 ,  G01N2035/1039 ,  Y10T436/11

    Abstract: A method and apparatus for preventing or limiting damage to capillaries used to dispense microdrops measures the voltage produced by a piezoelectric transducer when the capillary contacts a solid surface or the phase shift occurring when the piezoelectric transducer is operated at its resonant frequency. After distinguishing the voltage created from such contact from the voltage produced from unrelated random sources, corrective action is taken, in one aspect by stopping the relative movement of the capillary and the surface being contacted. The method and apparatus may also be employed to determine the position of a solid or liquid surface.

Patent Agency Ranking