公开(公告)号：EP1404616A4

公开(公告)日：2006-09-13

申请号：EP02749614

申请日：2002-06-20

申请人： PG RES FOUNDATION INC

发明人： BOND ANDREW H ,  HORWITZ E PHILIP

IPC分类号： C01G29/00 ,  B01D15/26 ,  B01D15/36 ,  B01J39/04 ,  G01N30/08 ,  G01N30/46 ,  G01N30/88 ,  G21G4/08

CPC分类号： G01N30/88 ,  B01D15/265 ,  B01D15/362 ,  B01J39/04 ,  G01N30/468 ,  G01N2030/085 ,  G01N2030/77 ,  G01N2030/8804 ,  G01N2030/8868 ,  G21G1/0005 ,  G21G4/08 ,  Y10S423/07

摘要： A multicolumn selectivity inversion generator has been developed in which bismuth-213 is selectively extracted from an HC1 solution of the actinium-225 parent (and its radiogenic descendents) by a primary separation column containing a separation medium containing a neutral oxygenated organophosphorus extractant. After rinsing with dilute HC1, the bismuth-213 is stripped with a buffered NaC1 solution. The stripped solution is passed through a cation-exchange resin guard column that retains the actinium-225 and radium-225 contaminants while the bismuth-213 elutes. This generator method minimizes the unpredictable effects of radiation damage to the support material and permits the reliable production of bismuth-213 of high chemical and radionuclidic purity.

公开(公告)号：EP1404430A4

公开(公告)日：2006-08-09

申请号：EP02749637

申请日：2002-06-21

申请人： PG RES FOUNDATION INC

发明人： BOND ANDREW H ,  HINES JOHN H ,  YOUNG JOHN E ,  HORWITZ PHILIP E

IPC分类号： B01D15/08 ,  B01D15/26 ,  B01D15/36 ,  B01J39/04 ,  G01N30/08 ,  G01N30/46 ,  G01N30/88 ,  G21G4/08

CPC分类号： G21G1/0005 ,  B01D15/265 ,  B01D15/362 ,  B01J39/04 ,  G01N30/468 ,  G01N30/88 ,  G01N2030/085 ,  G01N2030/77 ,  G01N2030/8804 ,  G01N2030/8868 ,  G01N2030/8872 ,  G21G4/08

摘要： A gas-free system for separating a solution of substantially impurity-free daughter products from an associated parent load solution includes a pump (16), a plurality of multi-port valves (18, 20, 22), separation medium (24) and a processor. An uncoiled conduit (38) extends between a third port of a second multi-port valve (20) and a first multi-port valve (18). A processor is operably coupled to a pump (16), and the plurality of multi-port valves (18, 20, 22). A method for separating a solution of substantially impurity-free daughter product from an associated parent load solution is also disclosed.

公开(公告)号：EP1404429A4

公开(公告)日：2005-02-02

申请号：EP02749624

申请日：2002-06-21

申请人： PG RES FOUNDATION INC

发明人： YOUNG JOHN E ,  HINES JOHN J

IPC分类号： G01N30/86 ,  B01D15/10 ,  B01D15/18 ,  G01N30/08 ,  G01N30/46 ,  G01N30/62 ,  G01N30/88 ,  G01T1/29 ,  G01T7/08 ,  G21H5/02 ,  B01D15/08

CPC分类号： B01D15/10 ,  B01D15/1864 ,  G01N30/468 ,  G01N30/8651 ,  G01N30/88 ,  G01N2030/085 ,  G01N2030/8804 ,  G01N2030/8809 ,  G21G1/0005 ,  Y10S422/903

摘要： A method and apparatus are provided for automatically separating radionuclides using a chromatographic separation process. The method includes the steps of displaying a first flow diagram on a display depicting flow of the radionuclides through a first set of separation elements of the plurality of separation processing elements, but only during a first step of the chromatographic separation process and displaying a second flow diagram on the display depicting flow of the radionuclides through a second set of separation elements of the plurality of separation processing elements, but only during a second step of the chromatographic separation process.

公开(公告)号：EP1453813A4

公开(公告)日：2005-02-09

申请号：EP02786628

申请日：2002-11-01

申请人： PG RES FOUNDATION

发明人： BOND ANDREW H ,  BARRANS RICHARD E ,  HORWITZ E PHILIP

IPC分类号： B01D11/04 ,  C01G99/00 ,  C07B63/00 ,  C07C37/86 ,  C07C39/17 ,  C07C41/44 ,  C07C43/21 ,  C07D259/00 ,  C07D323/00 ,  C07D327/00 ,  C07D487/22 ,  C07D498/08 ,  C07D245/00 ,  C01G57/00 ,  C07D255/00 ,  C07D313/00 ,  C07D321/00

CPC分类号： C07D323/00

摘要： A purification method is disclosed for a predetermined water-insoluble extractant present in a liquid phase composition that additionally contains one or more additional extractants, synthesis reaction starting materials, and reaction byproducts dissolved as solutes in an organic diluent. An ion-containing compound is admixed with the composition to form an extractant/ion complex in the organic diluent phase that has an affinity for a new phase that is greater than the affinity for the first-named phase. The predetermined extractant/ion complex is separated from the diluent by using the new phase affinity, and the extractant/ion complex is preferably although not necessarily recovered. The extractant/ion complex is separated into extractant and ion. The extractant is recovered. Exemplary extractants include polyethers, crown ethers, crown thioethers, calixarenes, polyamines, cryptands, porphyrins and the like.

公开(公告)号：EP1499412A4

公开(公告)日：2007-07-11

申请号：EP03723992

申请日：2003-04-10

申请人： PG RES FOUNDATION

发明人： HORWITZ PHILIP E ,  BOND ANDREW H

IPC分类号： C01G29/00 ,  G21G4/08

CPC分类号： G21G4/08 ,  G21G1/0005

摘要： Disclosed is a process for producing a solution of a daughter radionuclide that is substantially free of impurities by contacting an aqueous parent-daughter radionuclide solution with a first separation medium, eg. Chromatographic column. The product solution of the desired daughter radionuclide is then contacted with a second separation medium to produce a pure daughter radionuclide solution.

公开(公告)号：EP1458805A4

公开(公告)日：2004-10-20

申请号：EP02784000

申请日：2002-10-03

申请人： UNIV ALABAMA ,  PG RES FOUNDATION INC

发明人： SWATLOSKI RICHARD PATRICK ,  ROGERS ROBIN DON ,  HOLBREY JOHN DAVID

IPC分类号： C08B16/00 ,  C05G5/00 ,  C08B1/00 ,  C08J3/09 ,  C08J3/28 ,  C08L1/06 ,  C12N11/12 ,  D01F2/02 ,  C08L1/02

CPC分类号： C08J3/096 ,  C08B1/003 ,  C08J3/28 ,  C08J2301/02 ,  C08L1/06 ,  C12N11/12 ,  D01F2/02 ,  Y10T428/31772 ,  Y10T428/31971

摘要： Cellulose is dissolved in an ionic liquid without derivatization, and is regenerated in a range of structural forms without requiring the use of harmful or volatile organic solvents. Cellulose solubility and the solution properties can be controlled by the selection of the ionic liquid constituents, with small cations and halide or pseudohalide anions favoring solution.