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10 条记录 (耗时 0.012 秒)

    METHODS AND KITS FOR DETECTING, DIAGNOSING AND MONITORING DISEASES
    5.
    发明公开
    METHODS AND KITS FOR DETECTING, DIAGNOSING AND MONITORING DISEASES 有权
    方法和试剂盒进行检测，疾病的诊断和监测

    公开(公告)号：EP2440925A1

    公开(公告)日：2012-04-18

    申请号：EP09779678.3

    申请日：2009-06-08

    申请人： Protea Biopharma N.v.

    发明人： ROELANT, Christiaan ,  DE MEIRLEIR, Kenny

    IPC分类号： G01N33/52

    CPC分类号： G01N33/52 ,  Y10T436/18

    摘要： The invention provides methods and kits for detecting metabolites in a body fluid by contacting a sample of the body fluid with at least one reducible dye at a pH-value which is higher than the pKa-value of the reducible dye, whereby a color change resulting from reduction of the reducible dye is indicative of the presence of metabolites in the body fluid. The methods and kits are of use in the detection and monitoring of disease conditions.

    METHODS AND COMPOSITIONS FOR EVALUATING CHRONIC IMMUNE DISEASES
    7.
    发明公开
    METHODS AND COMPOSITIONS FOR EVALUATING CHRONIC IMMUNE DISEASES 有权
    方法和组合物评估慢性免疫疾病

    公开(公告)号：EP2401400A2

    公开(公告)日：2012-01-04

    申请号：EP10716040.0

    申请日：2010-02-26

    申请人： Protea Biopharma N.V.

    发明人： FREMONT, Marc ,  DE MEIRLEIR, Kenny, Leo

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6883 ,  C12Q2600/156

    摘要： Methods and compositions are provided for evaluating a subject for chronic immune disease, including predicting whether a subject is susceptible to a chronic immune disease, diagnosing whether a subject has a chronic immune disease and/or determining a treatment for a subject suffering from a chronic immune disease. Aspects of the methods include genotyping a subject to determine whether the subject has a least one polymorphism in at least one gene chosen from TLR4, Hsp60, IL-23R, IL-6 and IL-17F. In addition, reagents, devices and kits thereof that find use in practicing the subject methods are provided.

    Macrophage Activating Factor for treatment of endometriosis
    8.
    发明公开
    Macrophage Activating Factor for treatment of endometriosis 审中-公开
    巨噬细胞活化物Faktor zur Behandlung der子宫内膜异位症

    公开(公告)号：EP2687264A1

    公开(公告)日：2014-01-22

    申请号：EP12176723.0

    申请日：2012-07-17

    申请人： Protea Biopharma N.V.

    发明人： Roelant, Christiaan ,  De Meirleir, Kenny

    IPC分类号： A61P15/00 ,  A61K38/19 ,  A61K31/525 ,  G01N33/50

    CPC分类号： A61K38/19 ,  A61K31/525 ,  G01N33/6893 ,  G01N2800/364

    摘要： The present invention relates to methods and compounds for the treatment and prevention of endometriosis and/or symptoms associated with endometriosis in a patient. More particularly, compositions comprising a Macrophage Activating Factor for use in the treatment or prevention of endometriosis and/or symptoms associated therewith are envisaged.

    摘要翻译： 本发明涉及用于治疗和预防与患者子宫内膜异位症相关的子宫内膜异位和/或症状的方法和化合物。 更具体地，设想包含用于治疗或预防子宫内膜异位症和/或与其相关的症状的巨噬细胞活化因子的组合物。