公开(公告)号：EP0892664A1

公开(公告)日：1999-01-27

申请号：EP97915100.0

申请日：1997-03-07

申请人： Baxter Research Medical, Inc.

发明人： McREA, James, C. ,  POULSON, Stephanie ,  XIA, Yong, Nian ,  FOWERS, Kirk

IPC分类号： A61M1 ,  B01D61 ,  B01D63 ,  B01D71

CPC分类号： B01D61/145 ,  A61M1/3427 ,  A61M1/3472 ,  A61M1/3475 ,  A61M1/3482 ,  A61M1/3493 ,  A61M1/3603 ,  A61M1/3621 ,  A61M1/3675 ,  B01D61/00 ,  B01D61/142 ,  B01D61/243 ,  B01D63/046 ,  B01D2313/40 ,  B01D2315/06

摘要： Methods and apparatuses for salvaging blood from a patient are disclosed. A blood salvaging circuit (140) coupled to a cardiopulmonary bypass circuit (144) includes a hemoconcentrator (152) and a sorbent-containing plasma separator. A combination device (142) for salvaging blood includes a closed plasma chamber (172) containing a plasma chamber solution (176), a hollow fiber plasma-separating membrane (156) for receiving blood and permitting plasma to be transported therethrough into the plasma chamber solution (176) and for refiltering the treated plasma back into the blood salvaging circuit (140), a selective sorbent (180) for contacting the selected solute in the plasma and binding the selected solute and an ultrafiltration membrane (184) for removing water, fluids and low molecular weight components from the plasma.

公开(公告)号：EP0643614A1

公开(公告)日：1995-03-22

申请号：EP92911351.0

申请日：1992-04-30

申请人： RESEARCH MEDICAL, INC.

发明人： SHETTIGAR, Udipi ,  MCREA, James, C.

IPC分类号： A61M1 ,  B01D61 ,  B01D63

CPC分类号： B01D61/145 ,  A61M1/3472 ,  A61M1/3475 ,  A61M1/3486 ,  B01D63/02 ,  B01D63/024 ,  B01D2313/40 ,  B01D2315/06 ,  Y10T436/255

摘要： A system and method of achieving both convective and diffusive transport of plasma across a membrane (30) accompanied by the selective removal of plasma components using sorbents (33) followed by reinfusion of the purified plasma in a blood circulation system is achieved by pumping blood through a filter (30) comprising a bundle of ''U'' shaped hollow fibers immersed in a closed plasma chamber (31) containing sorbents (33) in a plasma chamber solution (32). As blood flows through the entry arm (32), due to positive transmembrane pressure difference, plasma filtration into the plasma chamber (31) occurs. However, the transmembrane pressure difference is negative when blood flows out of the exit arm (39) of filter (30) and the direction of filtration reverses causing reverse filtration/reinfusion of plasma from the chamber (31) into the blood in the exit arm (39).

公开(公告)号：EP0643614B1

公开(公告)日：1999-12-29

申请号：EP92911351.2

申请日：1992-04-30

申请人： Baxter Research Medical, Inc.

发明人： SHETTIGAR, Udipi ,  MCREA, James, C.

IPC分类号： B01D61/00 ,  B01D63/02

CPC分类号： B01D61/145 ,  A61M1/3472 ,  A61M1/3475 ,  A61M1/3486 ,  B01D63/02 ,  B01D63/024 ,  B01D2313/40 ,  B01D2315/06 ,  Y10T436/255

公开(公告)号：EP0411039A1

公开(公告)日：1991-02-06

申请号：EP89905531.0

申请日：1989-04-27

申请人： RESEARCH MEDICAL, INC.

发明人： BUCKBERG, Gerald, D. ,  TODD, Robert, J.

IPC分类号： A61F2 ,  A61M25

CPC分类号： A61M25/1029 ,  A61M25/0075 ,  A61M25/1002 ,  A61M25/1027 ,  A61M2025/1086

摘要： Cette invention concerne un cathéter de cardioplégie rétrograde (10) et son procédé d'utilisation. Le cathéter présente deux passages, un passage de perfusion (18) au travers duquel s'écoule la solution cardioplégique et un passage de détection de pression (20) pour contrôler la pression du fluide au point où la solution sort du cathéter. Un ballon légèrement conique à auto-remplissage (22) est fixé à l'extrémité distale du cathéter (10). De même, une pointe arrondie et douce (14) est fixée à l'extrémité distale du cathéter pour empêcher d'endommager les tissus sensibles du sinus coronaire (50). Un stylet (36) ayant une poignée (38) à une extrémité et une courbure prédéterminée à l'autre extrémité permet d'introduire de manière précise et rapide le cathéter de cardioplégie (10) dans le sinus coronaire (50) au travers d'une très petite incision pratiquée dans l'orifice de l'oreillette droite. Après avoir fixé le cathéter, le stylet est enlevé.

公开(公告)号：EP0892664A4

公开(公告)日：1999-09-15

申请号：EP97915100

申请日：1997-03-07

申请人： BAXTER RESEARCH MEDICAL INC

发明人： MCREA JAMES C ,  POULSON STEPHANIE ,  XIA YONG NIAN ,  FOWERS KIRK

IPC分类号： A61M1/02 ,  A61M1/34 ,  A61M1/36 ,  B01D61/00 ,  B01D61/14 ,  B01D61/24 ,  B01D61/28 ,  B01D63/04 ,  B01D71/26 ,  B01D71/38 ,  B01D71/42 ,  B01D71/68 ,  B01D36/00 ,  B01D36/02 ,  B01D61/18 ,  B01D63/00 ,  B01D63/02 ,  B01D69/00 ,  B01D69/08

CPC分类号： B01D61/145 ,  A61M1/3427 ,  A61M1/3472 ,  A61M1/3475 ,  A61M1/3482 ,  A61M1/3493 ,  A61M1/3603 ,  A61M1/3621 ,  A61M1/3675 ,  B01D61/00 ,  B01D61/142 ,  B01D61/243 ,  B01D63/046 ,  B01D2313/40 ,  B01D2315/06

摘要： Methods and apparatuses for salvaging blood from a patient are disclosed. A blood salvaging circuit (140) coupled to a cardiopulmonary bypass circuit (144) includes a hemoconcentrator (152) and a sorbent-containing plasma separator. A combination device (142) for salvaging blood includes a closed plasma chamber (172) containing a plasma chamber solution (176), a hollow fiber plasma-separating membrane (156) for receiving blood and permitting plasma to be transported therethrough into the plasma chamber solution (176) and for refiltering the treated plasma back into the blood salvaging circuit (140), a selective sorbent (180) for contacting the selected solute in the plasma and binding the selected solute and an ultrafiltration membrane (184) for removing water, fluids and low molecular weight components from the plasma.

摘要翻译： 公开了用于从患者回收血液的方法和设备。 连接到心肺旁路回路（144）的血液回收回路（140）包括血液浓缩器（152）和含吸附剂的血浆分离器。 用于回收血液的组合装置（142）包括：包含等离子体腔室溶液（176）的封闭等离子体腔室（172）;用于接收血液并允许血浆通过其传输到等离子体腔室中的中空纤维等离子体分离膜（156） （176）并用于将经处理的血浆重新回到血液回收回路（140）中;选择性吸附剂（180），其用于接触等离子体中的选定溶质并结合所选溶质和超滤膜（184）以除去水; 流体和来自等离子体的低分子量组分。

公开(公告)号：EP0643614A4

公开(公告)日：1994-06-16

申请号：EP92911351

申请日：1992-04-30

申请人： RESEARCH MEDICAL INC

发明人： SHETTIGAR UDIPI ,  MCREA JAMES C

IPC分类号： A61M1/34 ,  B01D61/14 ,  B01D63/02 ,  B01D61/00

CPC分类号： B01D61/145 ,  A61M1/3472 ,  A61M1/3475 ,  A61M1/3486 ,  B01D63/02 ,  B01D63/024 ,  B01D2313/40 ,  B01D2315/06 ,  Y10T436/255

公开(公告)号：EP0411039A4

公开(公告)日：1991-04-10

申请号：EP89905531

申请日：1989-04-27

申请人： RESEARCH MEDICAL, INC.

发明人： BUCKBERG, GERALD, D. ,  TODD, ROBERT, J.

IPC分类号： A61F2/958 ,  A61M25/00

CPC分类号： A61M25/1029 ,  A61M25/0075 ,  A61M25/1002 ,  A61M25/1027 ,  A61M2025/1086

摘要： This invention relates to a retrograde cardioplegia catheter (10) and its method of use. The catheter contains two lumens, an infusion lumen (18) through which the cardioplegic solution flows and a pressure sensing lumen (20) for monitoring the fluid pressure at the point where the solution exits the catheter. A slightly tapered, self-filling balloon (22) is secured to the distal end of the catheter (10). Also, located at the distal end of the catheter is a soft, rounded tip (14) to prevent damage to the sensitive intimal tissues of the coronary sinus (50). A stylet (36) having a handle (38) at one end and a predetermined curve at the other end enables the cardioplegia catheter (10) to be inserted quickly and accurately within the coronary sinus (50) through a very small incision made in the right atrium. After the catheter is secured in place, the stylet is withdrawn.