公开(公告)号：EP3361986A2

公开(公告)日：2018-08-22

申请号：EP16855043.2

申请日：2016-10-14

申请人： Universidad de los Andes ,  Cells for Cells, S.P.A. ,  Acevedo, Juan Pablo ,  Wilkens, Camila ,  Khoury, Maroun ,  Rivet, Christopher

发明人： ACEVEDO, Juan Pablo ,  WILKENS, Camila ,  KHOURY, Maroun ,  RIVET, Christopher

IPC分类号： A61F2/00

CPC分类号： B29C41/22 ,  A61F2/04 ,  A61F2/06 ,  A61F2002/047 ,  A61F2210/0076 ,  A61F2240/001 ,  A61L27/18 ,  A61L27/20 ,  A61L27/222 ,  A61L27/26 ,  A61L27/34 ,  A61L27/3679 ,  A61L27/3834 ,  A61L27/3882 ,  A61L27/507 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/604 ,  A61L2300/608 ,  A61L2300/64 ,  A61L2420/02 ,  A61L2420/08 ,  A61L2430/22 ,  B29C41/14 ,  B29K2089/00 ,  B29L2031/7534 ,  B32B1/08 ,  B32B9/02 ,  B32B2535/00 ,  C08L89/00 ,  C08L67/04

摘要： The present invention overcomes all the above drawbacks and provides a versatile method for the fabrication of multilayer hollow tubes that uses a layer-by-layer rod dipping approach using different biomaterials. The device enables fine control over fabrication parameters, such as ascending/descending speeds, rod rotational velocity, and crosslinking or polymerization time. All these technologies allows the generation of more complex multilayer hollow tubes such as vessel-like structures, urethral grafting, prostate grafting and the like.