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公开(公告)号：EP3171905B1
公开(公告)日：2018-12-12
申请号：EP15730808.1
申请日：2015-06-24
申请人： Biotronik AG
CPC分类号： A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2210/0004 , A61F2240/001 , A61F2250/0068 , A61F2250/0098 , A61L31/022 , A61L31/028 , A61L31/08 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2400/18 , A61L2420/02 , A61L2420/06 , A61L2420/08
摘要： The invention is related to a biodegradable stent for vascular placement comprising, a tubular biodegradable metal structure, a biodegradable organic layer covering the surfaces of the structure, and optionally a biodegradable polymer coating covering the organic surface layer. The organic layer is a derivative of a monomer vapor injected plasma and is applied in a plasma enhanced chemical vapor deposition process. Thereby the biodegradable organic layer is an organosilane layer and the biodegradable polymer coating contains a therapeutic drug.
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公开(公告)号：EP2349363B1
公开(公告)日：2018-12-05
申请号：EP09819570.4
申请日：2009-10-09
申请人： MiMedx Group, Inc.
IPC分类号： A61L27/24 , A61L27/34 , A61L27/46 , A61L27/58 , A61L15/32 , A61F2/06 , A61B50/30 , A61L27/50 , A61F2/04 , A61B17/11
CPC分类号： A61L27/46 , A61B17/00491 , A61B17/0401 , A61B17/06166 , A61B17/1128 , A61B17/1146 , A61B50/30 , A61B2017/00526 , A61B2017/06052 , A61B2017/06071 , A61B2017/0608 , A61B2050/314 , A61F2/04 , A61F2/06 , A61F2/08 , A61F2/82 , A61F2210/0004 , A61F2210/0076 , A61F2230/0067 , A61F2230/0069 , A61F2240/00 , A61F2240/001 , A61L15/325 , A61L27/14 , A61L27/24 , A61L27/26 , A61L27/34 , A61L27/50 , A61L27/507 , A61L27/54 , A61L27/56 , A61L27/58 , A61L31/044 , A61L2420/04 , A61L2420/08 , A61L2430/10 , A61L2430/32 , B29C53/58 , B29C53/66 , B32B37/142 , B32B37/20 , B32B38/08 , B32B2535/00 , Y10T428/249921 , Y10T428/2938 , Y10T442/3065 , C08L89/06
摘要： Methods for making collagen based biocomposite constructs and related devices include: (a) winding at least one collagen fiber a number of revolutions about a length of a support member having a long axis, the winding having at least one defined pitch and/or fiber angle relative to the long axis of the support member to form an elongate construct; and (b) applying a fluid polymeric material, such as, for example, an acrylate emulsion and/or other thermoplastic material, onto the collagen fiber during the winding step. Optionally, the fluid polymeric material can include antibiotics and/or other therapeutic agents for additional function/utility.
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公开(公告)号：EP3389735A1
公开(公告)日：2018-10-24
申请号：EP16826531.2
申请日：2016-12-18
IPC分类号： A61L27/34
CPC分类号： A61L31/10 , A61L27/34 , A61L2420/02 , A61L2420/08 , A61L27/16 , C08L65/04 , A61L27/18 , C08L71/02
摘要： A coating for an implantable medical device includes a poly(monochloro-p-xylylene) coating formed on at least a portion of the implantable medical device, and a layer including at least one of poly(ethylene glycol) and a poly(ethylene glycol) derivative linked to the poly(monochloro-p-xylylene) coating by covalent bonds.
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公开(公告)号：EP3361986A2
公开(公告)日：2018-08-22
申请号：EP16855043.2
申请日：2016-10-14
申请人： Universidad de los Andes , Cells for Cells, S.P.A. , Acevedo, Juan Pablo , Wilkens, Camila , Khoury, Maroun , Rivet, Christopher
IPC分类号： A61F2/00
CPC分类号： B29C41/22 , A61F2/04 , A61F2/06 , A61F2002/047 , A61F2210/0076 , A61F2240/001 , A61L27/18 , A61L27/20 , A61L27/222 , A61L27/26 , A61L27/34 , A61L27/3679 , A61L27/3834 , A61L27/3882 , A61L27/507 , A61L27/54 , A61L27/58 , A61L2300/604 , A61L2300/608 , A61L2300/64 , A61L2420/02 , A61L2420/08 , A61L2430/22 , B29C41/14 , B29K2089/00 , B29L2031/7534 , B32B1/08 , B32B9/02 , B32B2535/00 , C08L89/00 , C08L67/04
摘要： The present invention overcomes all the above drawbacks and provides a versatile method for the fabrication of multilayer hollow tubes that uses a layer-by-layer rod dipping approach using different biomaterials. The device enables fine control over fabrication parameters, such as ascending/descending speeds, rod rotational velocity, and crosslinking or polymerization time. All these technologies allows the generation of more complex multilayer hollow tubes such as vessel-like structures, urethral grafting, prostate grafting and the like.
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公开(公告)号：EP3347063A1
公开(公告)日：2018-07-18
申请号：EP16845145.8
申请日：2016-09-09
CPC分类号： A61L27/34 , A61L27/3633 , A61L27/56 , A61L2420/08 , A61L2430/20 , C08L89/00 , C08L75/04
摘要： Provided herein is a bilayer medical device (e.g., “patch”) for use in treating ischemic cardiomyopathy as well as for treatment of other conditions. The medical device comprises a first, support layer and a second, ECM-containing layer over the first layer. Methods of making and using the device also are provided herein.
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公开(公告)号：EP3344300A1
公开(公告)日：2018-07-11
申请号：EP16759747.5
申请日：2016-08-31
申请人： CeramTec GmbH
CPC分类号： A61L27/56 , A61L27/306 , A61L27/32 , A61L2420/08 , A61L2430/02 , A61L2430/24
摘要： The present invention relates to implants, methods for the production thereof and the use thereof.
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公开(公告)号：EP3342433A1
公开(公告)日：2018-07-04
申请号：EP16207023.9
申请日：2016-12-27
CPC分类号： A61L31/028 , A61L31/088 , A61L31/148 , A61L2420/08
摘要： Die vorliegende Erfindung betrifft Stents hergestellt aus einer, unter physiologischen Bedingungen abbaubaren, Magnesiumlegierung mit einer anorganischen Beschichtung umfassend Magnesiumfluorid und mit einer organischen Beschichtung. Die erfindungsgemäßen Stents können dabei zusätzlich mit mindestens einem antiinflammatorischen, antiproliferativen, antiangiogenen, antirestenotischen und/oder antithrombogenen Wirkstoff beschichtet sein.
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公开(公告)号：EP3331585A1
公开(公告)日：2018-06-13
申请号：EP16833432.4
申请日：2016-04-14
CPC分类号： A61L31/024 , A61L31/084 , A61L31/122 , A61L31/146 , A61L31/16 , A61L2300/62 , A61L2300/64 , A61L2420/04 , A61L2420/08
摘要： Two-dimensional materials can be formed into enclosures for various substances and a substrate layer can be provided on an outside and/or on an inside of the enclosure, wherein the enclosure is not cytotoxic. The enclosures can be exposed to an environment, such as a biological environment (in vivo or in vitro), where the fibrous layer can promote vascular ingrowth. One or more substances within the enclosure can be released into the environment, one or more selected substances from the environment can enter the enclosure, one or more selected substances from the environment can be prevented from entering the enclosure, one or more selected substances can be retained within the enclosure, or combinations thereof. The enclosure can, for example, allow a sense-response paradigm to be realized. The enclosure can, for example, provide immunoisolation for materials, such as living cells, retained therein.
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公开(公告)号：EP3331584A1
公开(公告)日：2018-06-13
申请号：EP16833502.4
申请日：2016-07-18
发明人： HASAN, David
CPC分类号： A61L31/088 , A61F2/90 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61L27/04 , A61L27/306 , A61L27/54 , A61L31/022 , A61L31/08 , A61L31/16 , A61L2300/414 , A61L2300/42 , A61L2420/08 , B82Y5/00
摘要： The present invention is directed to improved coatings and coating methods for medical devices.
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公开(公告)号：EP3043838B1
公开(公告)日：2018-06-06
申请号：EP14784004.5
申请日：2014-09-08
发明人： Rübben Alexander
IPC分类号： A61L31/10 , A61L27/34 , A61L27/54 , B05D1/00 , C09D105/02
CPC分类号： A61L27/54 , A61L27/34 , A61L31/10 , A61L2300/606 , A61L2300/608 , A61L2420/02 , A61L2420/08 , B05D1/002 , C09D105/02
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