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27 条记录 (耗时 0.012 秒)

    Production of connectors for interlocking containers placed side-by-side
    2.
    发明公开
    Production of connectors for interlocking containers placed side-by-side 失效
    VerbindungsvorrichtungfürübereinandergesetzteBehälter。

    公开(公告)号：EP0155154A2

    公开(公告)日：1985-09-18

    申请号：EP85301618.6

    申请日：1985-03-08

    申请人： SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION

    发明人： Claxton, Nigel Ervine

    IPC分类号： B65D21/02

    CPC分类号： B65D5/005 ,  B65D5/0055 ,  B65D21/0201

    摘要： A method of cutting a blank from which a container can be erected is disclosed, the blank being cut from a rectangular sheet of cardboard, corrugated board etc. The shape of the blank is such that corner portions of the sheet are cut away as waste. These corner portions are trimmed to rectangular shape, simultaneously with the cutting of the blank, and one or more slots are cut in them. These trimmed portions are used in a stack of containers to interlink upstanding pegs of adjacent containers, the pegs being passed through said slots.

    摘要翻译： 公开了一种切割容器可以竖立的坯料的方法，坯料从矩形纸板，瓦楞纸板等切割。坯料的形状使得片材的拐角部分作为废料被切除。 这些角部被切割成矩形，同时切割坯料，并且在其中切割一个或多个槽。 这些修剪部分用于堆叠的容器中以将相邻容器的直立钉相互连接，钉穿过所述槽。

    Shrink-resist treatment of wool
    4.
    发明公开
    Shrink-resist treatment of wool 失效
    羊毛的抗皱处理

    公开(公告)号：EP0080272A3

    公开(公告)日：1984-08-22

    申请号：EP82305728

    申请日：1982-10-28

    申请人： SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION

    发明人： Barkhuysen, Francois Albertus ,  Van Rensburg, Nicolaas Jacobus Janse

    IPC分类号： D06M03/08 ,  D06M15/54

    CPC分类号： D06M11/30

    摘要： A method for the shrinkresist treatment of wool including the steps of chlorinating the wool with an acidified hypochlorite; dechlorinating the product; acidifying the product; and applying an acid colloid solution of suitable methylolmelamine resin to the product. The chlorination is preferably carried out in a suction drum in such a manner that the level of active chlorine on the wool is in excess of 2% (m/m).

    摘要翻译： 用于羊毛的抗皱处理的方法，包括用酸化的次氯酸盐对羊毛进行氯化的步骤：对产品进行脱氯; 酸化产品; 并将合适的羟甲基三聚氰胺树脂的酸胶体溶液施加到产品上。 氯化反应优选在抽吸鼓中进行，使得羊毛上的活性氯水平超过2％（m / m）。

    Plasminogen activator
    5.
    发明公开
    Plasminogen activator 失效
    Plasminogenaktivator。

    公开(公告)号：EP0112122A2

    公开(公告)日：1984-06-27

    申请号：EP83307468.5

    申请日：1983-12-08

    申请人： SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION

    发明人： Dowdle, Eugene Bernard Davey

    IPC分类号： C12N9/72 ,  A61K37/54

    CPC分类号： C12N9/6459 ,  A61K38/00 ,  C12Y304/21069 ,  Y10S435/814 ,  Y10S435/815

    摘要： The invention provides a process for producing a purified plasminogen activator substance based on the TPA/pro-TPA couple. Pro-TPA yielding cell cultures are cultivated in a suitable culture medium in the absence of enzymes which catalyse the conversion of pro-TPA into TPA or where such enzymes are present in the presence of a suitable inhibitor adapted to inhibit such enzymes. Accord- : ingly the couple is represented in the harvesting liquid by at least 50 to 100% of pro-TPA and can in fact be virtually 100% pro-TPA, any balance being TPA. The harvesting fluid is treated with an affinity reagent comprising an immobilised Kunitz type inhibitor of the type occurring in seeds of Erythrina latissima and other Erythrina species (DE-3) to selectively adsorb the pro-TPA and any TPA in the harvesting fluid, followed by desorption of pro-TPA and optionally TPA. The pro-TPA so recoverable has 1/10 the plasminogen activating properties of TPA. It is convertable into active TPA enzymatically, e.g. by plasmin or by enzymes present in fibrin clots. The pro-TPA has a higher affinity for fibrin and better selectivity than TPA. It is used for the management and prophylaxis of thrombosis and embolism in dosages of pro-TPA/TPA couple which result in less than 50%, e.g. less than 20% of the plasminogen activating activity resulting from up to 15 mg/24 hrs pure TPA.

    摘要翻译： 本发明提供了一种基于TPA /亲-TPA对产生纯化的纤溶酶原激活物质的方法。 在不存在催化TPA转化成TPA的酶的情况下，在合适的培养基中培养产生Pro-TPA的细胞培养物，或者在适合抑制这种酶的合适的抑制剂的存在下存在这些酶。 因此，该对在采收液中表现出至少50％至100％的亲TPA，实际上可以实际上为100％的亲TPA，任何余量均为TPA。 采用亲和试剂处理收获液，所述亲和试剂包含存在于鸢尾花（Erythrina latissima）和其它鸢尾属种（DE-3）的种子中的固定化的Kunitz型抑制剂，以选择性吸附收获液中的原TPA和任何TPA， 亲TPA和任选的TPA的解吸。 TPA的原始TPA具有TPA纤溶酶原活化性质的1/10。 它可酶促转化成活性TPA，例如 通过纤溶酶或存在于纤维蛋白凝块中的酶。 前TPA对纤维蛋白具有更高的亲和力，并且比TPA具有更好的选择性。 用于治疗和预防TPA / TPA夫妇的血栓形成和栓塞的剂量，导致少于50％，例如， 少于20％的纤维蛋白溶酶原激活活性，由高达15mg / 24小时的纯TPA引起。

    Plasminogen activator
    7.
    发明公开
    Plasminogen activator 失效
    纤溶酶原激活剂

    公开(公告)号：EP0112122A3

    公开(公告)日：1987-04-01

    申请号：EP83307468

    申请日：1983-12-08

    申请人： SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION

    发明人： Dowdle, Eugene Bernard Davey

    IPC分类号： C12N09/64 ,  A61K37/54

    CPC分类号： C12N9/6459 ,  A61K38/00 ,  C12Y304/21069 ,  Y10S435/814 ,  Y10S435/815

    摘要： The invention provides a process for producing a purified plasminogen activator substance based on the TPA/pro-TPA couple. Pro-TPA yielding cell cultures are cultivated in a suitable culture medium in the absence of enzymes which catalyse the conversion of pro-TPA into TPA or where such enzymes are present in the presence of a suitable inhibitor adapted to inhibit such enzymes. Accord- : ingly the couple is represented in the harvesting liquid by at least 50 to 100% of pro-TPA and can in fact be virtually 100% pro-TPA, any balance being TPA. The harvesting fluid is treated with an affinity reagent comprising an immobilised Kunitz type inhibitor of the type occurring in seeds of Erythrina latissima and other Erythrina species (DE-3) to selectively adsorb the pro-TPA and any TPA in the harvesting fluid, followed by desorption of pro-TPA and optionally TPA. The pro-TPA so recoverable has 1/10 the plasminogen activating properties of TPA. It is convertable into active TPA enzymatically, e.g. by plasmin or by enzymes present in fibrin clots. The pro-TPA has a higher affinity for fibrin and better selectivity than TPA. It is used for the management and prophylaxis of thrombosis and embolism in dosages of pro-TPA/TPA couple which result in less than 50%, e.g. less than 20% of the plasminogen activating activity resulting from up to 15 mg/24 hrs pure TPA.

    摘要翻译： 本发明提供了基于TPA / pro-TPA对生产纯化的纤溶酶原激活物质的方法。 Pro-TPA产生细胞培养物在不存在催化原-TPA转化成TPA的酶的情况下在合适的培养基中培养，或者其中这些酶在适合抑制这些酶的合适抑制剂存在下存在。 相应地，这对夫妇在采收液中代表至少50-100％的亲TPA，事实上可以是几乎100％的亲TPA，任何余量都是TPA。 收获液用亲和试剂处理，所述亲和试剂包含在Erythrina latissima和其他刺桐属物种（DE-3）的种子中存在的固定Kunitz型抑制剂，以选择性吸附收获液中的原-TPA和任何TPA，接着 pro-TPA和任选的TPA的解吸。 可以回收的亲TPA具有1/10的TPA的纤溶酶原激活性质。 它可以酶促转化成活性TPA，例如。 纤溶酶或纤维蛋白凝块中存在的酶。 亲TPA对纤维蛋白具有更高的亲和力，并且比TPA具有更好的选择性。 它用于治疗和预防血栓形成和栓塞，TPA / TPA对的剂量小于50％，例如， 由高达15mg / 24小时纯TPA产生的纤溶酶原激活活性小于20％。

    Composite floor structures
    9.
    发明公开
    Composite floor structures 失效
    天花板在复合材料结构。

    公开(公告)号：EP0104992A1

    公开(公告)日：1984-04-04

    申请号：EP83401823.6

    申请日：1983-09-19

    申请人： SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION

    发明人： Boswel, Justus Alfred Theodoor

    IPC分类号： E04B5/36

    CPC分类号： E04B5/38 ,  E04B5/40

    摘要： A composite floor structure comprising a floor slab (A1) of concrete or other compression resistant material (11) and at least one reinforced beam (B1) under the floor slab (A1). The beam (B1) comprises permanent shuttering including an open-mouthed, upwardly facing channel formation (1a) of steel or other tension resistant material; and a plurality of transverse members (5a) spaced apart along the length of the channel formation (1a) and extending transversely to the channel formation (1a) across substantially the entire width of the mouth of the channel formation (1a). Each transverse member (5a) is fast with the channel formation (1a) in the region of its mouth in zones (7a) on opposite sides of the mouth and at least part of at least certain of the transverse members (5a) extends upwardly from the region of the mouth of the channel formation (1a) into the overlying floor slab (A1). Concrete or other compression resistant material (11) is located in the channel formation (1a) and is formed integrally with the compression resistant material (11) of the floor slab (A1).