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32 条记录 (耗时 0.013 秒)

    Liquid parenteral formulation comprising a tramadol material and paracetamol
    3.
    发明公开
    Liquid parenteral formulation comprising a tramadol material and paracetamol 审中-公开
    Flüssige肠胃外制剂，死亡乙酰氨基酚和对乙酰氨基酚umfasst

    公开(公告)号：EP2377514A2

    公开(公告)日：2011-10-19

    申请号：EP11003295.0

    申请日：2011-04-19

    申请人： Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.

    发明人： Ioulia, Tseti

    IPC分类号： A61K9/00 ,  A61K31/135 ,  A61K31/167 ,  A61K47/02 ,  A61K47/10 ,  A61K47/18

    CPC分类号： A61K9/0019 ,  A61K31/135 ,  A61K31/167 ,  A61K47/02 ,  A61K47/10 ,  A61K47/183 ,  A61K2300/00

    摘要： The present invention provides a liquid parenterally deliverable formulation comprising a tramadol material, particularly tramadol HCl, and paracetamol and its use in treating conditions or disorder wherein an urgent treatment with analgesics is indicated.
    This formulation is particularly useful whenever fast relief is required in lesser time, especially in acute or chronic painful conditions.
    The formulation of the present invention is stable upon storage at room temperature and in refrigerated temperature.

    摘要翻译： 本发明提供了包含曲马多材料，特别是曲马多HCl和对乙酰氨基酚的液体肠胃外可输送制剂及其用于治疗其中指示使用止痛剂的紧急治疗的病症或障碍的用途。 当在更短的时间内需要快速缓解时，特别是在急性或慢性疼痛状况下，该制剂特别有用。 本发明的制剂在室温和冷藏温度下储存时是稳定的。

    Effervescent formulations comprising a phosphonate and methods for their preparation
    4.
    发明公开
    Effervescent formulations comprising a phosphonate and methods for their preparation 有权
    Efferveszenzformulierungen mit einem Phosphonat und Herstellungsverfahrendafür

    公开(公告)号：EP2283823A1

    公开(公告)日：2011-02-16

    申请号：EP09009791.6

    申请日：2009-07-29

    申请人： Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. ,  Tseti, Ioulia

    发明人： Tseti, Ioulia

    IPC分类号： A61K9/20 ,  A61K9/16

    CPC分类号： A61K9/0007 ,  A61K9/1611 ,  A61K9/2009

    摘要： The invention provides an effervescent pharmaceutical composition comprising a biphosphonate compound or its pharmaceutically acceptable salt, a carbonate source, an acid source, a divalent metal salt as humidity moderator and a divalent cation scavenger, wherein the molar ratio of divalent cation scavenger to humidity moderator is at least 0.8/1. This composition makes the production of effervescent formulations comprising biphosphonate compounds easier, since less stringent controls or even no control of environmental humidity conditions have to be carried out during the production of the product. Moreover, the final product is protected against the negative impact of humidity, which may induce disintegration during the shelf-life of the product.

    摘要翻译： 本发明提供了包含二膦酸盐化合物或其药学上可接受的盐，碳酸盐源，酸源，作为调湿剂的二价金属盐和二价阳离子清除剂的泡腾药物组合物，其中二价阳离子清除剂与湿度调节剂的摩尔比为 至少0.8 / 1。 该组合物使得包含双膦酸酯化合物的泡腾制剂的生产更容易，因为在产品生产期间必须进行不太严格的控制或甚至不控制环境湿度条件。 此外，最终产品可以防止潮湿的负面影响，这可能在产品的保质期内引起分解。

    Topical pharmaceutical and medical device preparations containing combinations of sucralfate, hyaluronic acid, arginine and a natural moisturizing agent
    10.
    发明公开
    Topical pharmaceutical and medical device preparations containing combinations of sucralfate, hyaluronic acid, arginine and a natural moisturizing agent 审中-公开
    用于局部应用的药物制剂含有硫糖铝，透明质酸，精氨酸，和天然润肤

    公开(公告)号：EP2810641A1

    公开(公告)日：2014-12-10

    申请号：EP14386014.6

    申请日：2014-05-30

    申请人： Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.

    发明人： Tseti, Ioulia

    IPC分类号： A61K9/00 ,  A61K31/00 ,  A61K8/00

    CPC分类号： A61K9/006 ,  A61K9/0014 ,  A61K31/198 ,  A61K31/7024 ,  A61K31/728 ,  A61K2300/00

    摘要： The present application relates to topical preparations containing, based on the total weight of the composition:
    (A) 0.05-5.0 wt% sucralfate
    (B) 0.05-5.0 wt% hyaluronic acid or hyaluronate salt thereof
    (C) 0.05-5.0 wt% of a natural moisturizing agent (e.g. natural yogurt or yogurt derivatives or milk fermentation products or honey or honey products or mixtures thereof)
    (D) 0.05-5.0 wt% L-Arginine,
    (E) 80.0-98.0 wt% water And
    (F) 1.0-15.0 wt% of a carrier or vehicle, other than water.
    These preparations are stable and show rheological properties comparable to the ones of the compositions that are already in the market for similar uses, while the healing time is shorter and / or the clearance of skin lesions is of a higher degree and therefore, these combinations are useful in treating diseases or disorders of the skin or the oral cavity.

    摘要翻译： 本申请涉及包含，基于组合物的总重量，局部用制剂：（A）0.05-5.0重量％的硫糖铝（B）0.05-5.0％（重量）透明质酸或其盐的透明质酸（C）为0.05〜5.0重量％的 天然保湿剂（例如天然酸奶或酸奶的衍生物或乳发酵产品或蜂蜜或蜂蜜产品或它们的混合物）（D）0.05-5.0％（重量）L-精氨酸，（E）80.0-98.0％（重量）水和（F）1.0 载体或媒介物，除了水以外的-15.0％（重量）。 这些准备工作是稳定的，并显示流变性能堪比组合物的那些确实已经在市场上类似的用途，而愈合时间短和/或皮损的清除程度较高，因此，本文的组合是 治疗皮肤或口腔的疾病或病症是有用的。