摘要:
The present invention concerns a method for inducing differentiation of neuroectodermal oral stem cells, in particular from gingival tissue (GSCs), into osteoblasts by culturing them in an optimal serum-free medium supplemented by necessary components such as platelet lysate, growth hormone, heparin, and/or growth factors. The invention method provides osteoblasts for cell therapy, particularly for the restoration of bone defects in maxillary bones.
摘要:
This invention concerns a new method for differentiating oral neuroectodermal stem cells (CSO-NE), in particular human gingival neuroectodermal stem cells (CSGh), into oligodendrocytes (OL), and their use in the repair of the nervous system, in particular of head injuries.
摘要:
The invention relates to a novel use of ultrafine nanoparticles as an imaging agent in a method for diagnosing a renal disorder. The invention also relates to the use of ultrafine nanoparticles as an imaging agent in methods for monitoring the therapeutic effectiveness of a renal disorder treatment. Said nanoparticles include: (i) a polyorganosiloxane matrix (POS); (ii) one or more chelating agents grafted onto the POS matrix by -Si-C- covalent bonding; and (iii) one or more metal ions chelated by one or more of the aforementioned chelating agents.
摘要:
L'invention concerne une nouvelle utilisation de nanoparticules ultrafines comme agent d'imagerie dans une méthode de diagnostic d'une dysfonction rénale. L'invention vise également l'utilisation de nanoparticules ultrafines comme agent d'imagerie dans des méthodes de suivi de l'efficacité thérapeutique d'un traitement d'une dysfonction rénale. Lesdites nanoparticules comprennent (i) une matrice de polyorganosiloxane (POS), (ii) un ou plusieurs agents chélatants greffés à la matrice POS par liaison covalente -Si-C- et (iii) un ou plusieurs ions métalliques chélatés par un ou plusieurs des agents chélatants susmentionnés.