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公开(公告)号：EP2901159B1
公开(公告)日：2020-02-26
申请号：EP13783134.3
申请日：2013-09-30
发明人： RAJASEKARAN, John, J. , JAYARAMAN, Vasanth , WANG, Tianhao , BEI, Kang , KRISHNAMURTHY, Hari, Krishnan
IPC分类号： G01N33/543 , C40B30/04 , C40B40/10
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公开(公告)号：EP2920272B1
公开(公告)日：2019-08-21
申请号：EP13798499.3
申请日：2013-11-14
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公开(公告)号：EP3191629A1
公开(公告)日：2017-07-19
申请号：EP15839169.8
申请日：2015-09-10
发明人： RAJASEKARAN, John, J. , JAYARAMAN, Vasanth , BEI, Kang , WANG, Tianhao , KRISHNA, Karthik , KRISHNAMURTHY, Hari, Krishnan
CPC分类号： G01N33/564 , A61K38/10 , A61K39/00 , C07K7/08 , C40B40/10 , G01N33/6854 , G01N33/6878 , G01N2800/02 , G01N2800/24
摘要： The present disclosure relates generally to biomarkers and peptide arrays, and, more particularly, to a method of using a peptide array to identify biomarkers for an autoimmune disease such as, e.g., celiac disease. Furthermore, a set of novel biomarkers for celiac disease, having high sensitivity and specificity, are disclosed in addition to method of treatment using the novel biomarkers.
摘要翻译： 本公开内容一般涉及生物标志物和肽阵列，并且更具体地涉及使用肽阵列来鉴定自身免疫性疾病（例如乳糜泻）的生物标志物的方法。 此外，除了使用新型生物标志物的治疗方法之外，还公开了一组具有高灵敏度和特异性的乳糜泻新型生物标志物。
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公开(公告)号：EP2812344A1
公开(公告)日：2014-12-17
申请号：EP13747275.9
申请日：2013-02-07
申请人： Vibrant Holdings LLC
发明人： RAJASEKARAN, John, J. , KRISHNAMURTHY, Hari Krishnan , BEI, Kang , WANG, Tianhao , JAYARAMAN, Vasanth
CPC分类号： B01J19/0046 , B01J2219/00432 , B01J2219/00596 , B01J2219/00621 , B01J2219/00639 , B01J2219/00659 , B01J2219/00711 , B01J2219/00725 , C07K1/047 , C40B40/10 , G01N33/54353 , G01N2800/00
摘要： Disclosed herein are formulations, substrates, and arrays. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays. Also disclosed are methods for identifying peptide sequences useful for diagnosis and treatment of disorders, and methods for using the peptide sequences for diagnosis and treatment of disorders, e.g., celiac disorder. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules.
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公开(公告)号：EP4170348A1
公开(公告)日：2023-04-26
申请号：EP22199989.9
申请日：2016-03-14
发明人： RAJASEKARAN, John, J , WANG, Tianhao , BEI, Kang , JAYARAMAN, Vasanth , KRISHNAMURTHY, Hari, Krishnan
IPC分类号： G01N33/543 , B01J19/00
摘要： Disclosed herein are formulations, substrates, and arrays. In certain embodiments, methods of attaching a biomolecule to an array using a photoactivated conjugation compound are disclosed. Methods of generating site-specific attachment of biomolecules to an array are also disclosed. Arrays generated by these methods and methods of using these arrays are also disclosed.
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公开(公告)号：EP4030167A1
公开(公告)日：2022-07-20
申请号：EP22156994.0
申请日：2014-02-17
发明人： RAJASEKARAN, John J , JAYARAMAN, Vasanth , WANG, Tianhao , BEI, Kang , KRISHNAMURTHY, Hari Krishnan
IPC分类号： G01N33/543
摘要： Disclosed herein are formulations, substrates, and arrays. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays. Also disclosed are methods for identifying peptide sequences useful for diagnosis and treatment of disorders, and methods for using the peptide sequences for diagnosis and treatment of disorders, e.g., celiac disorder. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules.
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公开(公告)号：EP3864413A1
公开(公告)日：2021-08-18
申请号：EP19871323.2
申请日：2019-10-08
发明人： CHOUNG, Rok, Seon , MARIETTA, Eric, V. , JAYARAMAN, Vasanth , KRISHNA, Karthik , MURRAY, Joseph, A.
IPC分类号： G01N33/543 , G01N33/68 , G01N33/564 , C07K7/08
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公开(公告)号：EP3790985A1
公开(公告)日：2021-03-17
申请号：EP19799465.0
申请日：2019-05-09
发明人： RAJASEKARAN, John, J. , JAYARAMAN, Vasanth , VENUGOPAL, Anirudh , BEI, Kang , WANG, Tianhao , KRISHNA, Karthik , KRISHNAMURTHY, Hari, Krishnan
IPC分类号： C12Q1/68 , C12Q1/6837 , C40B50/00 , C40B50/14
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公开(公告)号：EP3702782A3
公开(公告)日：2020-11-11
申请号：EP20153448.4
申请日：2014-02-17
发明人： RAJASEKARAN, John J , JAYARAMAN, Vasanth , WANG, Tianhao , BEI, Kang , KRISHNAMURTHY, Hari Krishnan
IPC分类号： G01N33/543
摘要： Disclosed herein are formulations, substrates, and arrays. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays. Also disclosed are methods for identifying peptide sequences useful for diagnosis and treatment of disorders, and methods for using the peptide sequences for diagnosis and treatment of disorders, e.g., celiac disorder. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules.
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公开(公告)号：EP3107926B1
公开(公告)日：2020-09-09
申请号：EP15751793.9
申请日：2015-02-23
发明人： JAYARAMAN, Vasanth
IPC分类号： C07K1/04 , C07K1/10 , C07D257/04
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