公开(公告)号：EP2231137A4

公开(公告)日：2011-04-06

申请号：EP08871016

申请日：2008-12-18

申请人： YANG DAN ,  LI XIANG ,  SHEN BING ,  YAO XIAO-QIANG ,  THE CHINESE UNIVERSITY OF HONG KONG ,  VERSITECH LTD

发明人： YANG DAN ,  LI XIANG ,  SHEN BING ,  YAO XIAO-QIANG

IPC分类号： A61K31/16 ,  A61K31/215 ,  A61K31/4412 ,  A61P9/12 ,  A61P13/12 ,  A61P19/08 ,  A61P25/00 ,  A61P25/08 ,  A61P25/14 ,  A61P27/00 ,  C07C217/46 ,  C07C217/48 ,  C07C225/08 ,  C07C225/14 ,  C07C225/16 ,  C07C237/42 ,  C07C239/14 ,  C07C239/20 ,  C07D213/63 ,  C07D213/79 ,  C07D213/81

CPC分类号： A61K31/166

摘要： Provided herein are methods of modulating membrane potential of a cell membrane using self-assembling compounds. Also provided herein are methods of regulating a natural voltage-dependent ion channel in a cell membrane using the self-assembling compounds disclosed herein. Further provided herein are methods of treating, preventing and/or managing a disease that is related to the abnormal membrane potential responses by using the self-assembling compounds disclosed herein.

公开(公告)号：EP2231137A1

公开(公告)日：2010-09-29

申请号：EP08871016.5

申请日：2008-12-18

申请人： Yang, Dan ,  Li, Xiang ,  Shen, Bing ,  Yao, Xiao-qiang ,  The Chinese University Of Hong Kong ,  Versitech Limited

发明人： Yang, Dan ,  Li, Xiang ,  Shen, Bing ,  Yao, Xiao-qiang ,  The Chinese University Of Hong Kong ,  Versitech Limited

IPC分类号： A61K31/16 ,  A61K31/215 ,  A61K31/4412 ,  C07C239/14 ,  C07C239/20 ,  C07C217/48 ,  C07C217/46 ,  C07C237/42 ,  C07C225/08 ,  C07C225/14 ,  C07C225/16 ,  C07D213/63 ,  C07D213/79 ,  C07D213/81 ,  A61P9/12 ,  A61P27/00 ,  A61P13/12 ,  A61P25/14 ,  A61P25/08 ,  A61P25/00 ,  A61P19/08

CPC分类号： A61K31/166

摘要： Provided herein are methods of modulating membrane potential of a cell membrane using self-assembling compounds. Also provided herein are methods of regulating a natural voltage-dependent ion channel in a cell membrane using the self-assembling compounds disclosed herein. Further provided herein are methods of treating, preventing and/or managing a disease that is related to the abnormal membrane potential responses by using the self-assembling compounds disclosed herein.

公开(公告)号：EP4065550A1

公开(公告)日：2022-10-05

申请号：EP20893980.1

申请日：2020-11-23

申请人： Yang, Dan ,  Shen, Fangfang

发明人： Yang, Dan ,  Shen, Fangfang

IPC分类号： C07C239/20 ,  C07D209/12 ,  A61K31/166 ,  A61K31/404 ,  A61P35/00