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公开(公告)号：EP1784180A4
公开(公告)日：2009-07-22
申请号：EP05794980
申请日：2005-09-01
IPC分类号： A61K31/437 , A61P31/00 , A61P35/00 , C07D471/04
CPC分类号： C07D471/04 , C07D471/14
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公开(公告)号：EP1653955A4
公开(公告)日：2009-07-29
申请号：EP04780922
申请日：2004-08-12
发明人： KSHIRSAGAR TUSHAR A , AMOS DAVID T , DELLARIA JOSEPH F JR , HEPPNER PHILIP D , LANGER SCOTT E , ZIMMERMANN BERNHARD M
IPC分类号： C07D471/04 , A61K20060101 , A61K31/437 , A61K31/4375 , A61K31/4745 , A61P31/12 , A61P37/02 , C07D471/14
CPC分类号： C07D471/04 , C07D471/14
摘要： Imidazo-containing compounds (e.g., imidazoquinolines, imidazonaphthyridines, imidazopyridines) with a hydroxylamine substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
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3.发明公开HYDROXYLAMINE AND OXIME SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES 审中-公开羟胺肟 - 取代咪唑喹啉，咪唑并吡啶和咪唑并萘啶
公开(公告)号：EP1686992A4
公开(公告)日：2009-11-04
申请号：EP04812235
申请日：2004-11-24
发明人： KREPSKI LARRY R , DELLARIA JOSEPH F JR , DUFFY DANIEL E , AMOS DAVID T , ZIMMERMANN BERNHARD M , SQUIRE DAVID J , MARSZALEK GREGORY J , HEPPNER PHILIP D , KSHIRSAGAR TUSHAR A
IPC分类号： A61K31/44 , A61K20060101 , A61K31/42 , C07D471/02 , C07D471/06
CPC分类号： C07D471/04 , C07D471/14
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公开(公告)号：EP2850145A4
公开(公告)日：2016-02-10
申请号：EP13790686
申请日：2013-05-16
发明人： FUNG SIMON S , AMOS DAVID T , LIU JUNKANG J , DIETZ TIMOTHY M , MA JING , OPP CHARLES W
IPC分类号： C09J7/02 , C09J7/04 , C09J183/02
CPC分类号： A61L24/046 , A61M25/02 , A61M2025/0266 , C08G77/26 , C08L83/00 , C09J7/21 , C09J7/29 , C09J7/38 , C09J183/08 , C09J2201/20 , C09J2400/263 , C09J2400/28 , C09J2433/006 , C09J2475/006 , C09J2477/006 , C09J2483/00 , C09J2483/006
摘要： Adhesive articles suitable for use in medical applications include a siloxane-based pressure sensitive adhesive layer, and a breathable conformable backing having a first surface and a second surface. The siloxane-based pressure sensitive adhesive layer is coated on the first surface of the breathable conformable backing, and the second surface of the breathable conformable backing comprises a treated surface. The siloxane-based pressure sensitive adhesive layer can be attached to skin and other adhesive articles can be releasably adhered to the treated surface to form adhesive constructions.
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公开(公告)号：EP1682544A4
公开(公告)日：2009-05-06
申请号：EP04810969
申请日：2004-11-12
发明人： KSHIRSAGAR TUSHAR A , LUNDQUIST GREGORY D JR , AMOS DAVID T , DELLARIA JOSEPH F JR , ZIMMERMANN BERNHARD M , HEPPNER PHILIP D
IPC分类号： C07D471/00 , A61K20060101 , A61K31/44 , C07D471/04 , C07D471/14
CPC分类号： C07D471/04 , C07D471/14
摘要： Imidazo ring compounds (e.g., imidazoquinolines, 6, 7, 8, 9-tetrahydroimidazoquinolines, imidazonaphthyridines, and imidazopyridines) with a hydroxylamine substituent at the 2-position, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
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6.发明公开
公开(公告)号：EP1653914A4
公开(公告)日：2008-10-29
申请号：EP04780839
申请日：2004-08-12
发明人： KSHIRSAGAR TUSHAR , AMOS DAVID T , DELLARIA JOSEPH F JR , HEPPNER PHILIP D , LANGER SCOTT E , ZIMMERMANN BERNHARD M
IPC分类号： A61K6/00 , A61K20060101 , A61K31/437 , A61K31/4375 , A61K31/4745 , A61P31/12 , A61P37/02 , C07D471/04 , C07D471/14
CPC分类号： C07D471/04 , C07D471/14
摘要： Imidazo-containing compounds (e.g., imidazoquinolines, imidazonaphthyridines, and imidazopyridines) with an oxime substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
摘要翻译： 在1-位具有肟取代基的含咪唑的化合物（例如咪唑并喹啉类，咪唑并萘啶类和咪唑并吡啶类），含有这些化合物作为免疫调节剂的化合物，中间体和方法的药物组合物，用于在动物和动物中诱导细胞因子生物合成 披露了包括病毒和肿瘤疾病在内的疾病的治疗。
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公开(公告)号：EP2794799A4
公开(公告)日：2015-07-15
申请号：EP12858968
申请日：2012-12-20
IPC分类号： C09J183/04 , B32B27/06 , B32B33/00 , C08J3/28 , C08L83/04 , C08L83/08 , C09J183/08
CPC分类号： C09J7/0207 , A61F13/0253 , A61L15/225 , A61L15/585 , B05D3/068 , B32B2405/00 , C08G77/455 , C08K5/5419 , C08K2201/002 , C08L83/00 , C09J7/38 , C09J183/04 , C09J183/10 , C09J2483/00 , C09J2483/003 , Y10T428/2809 , Y10T428/2843 , Y10T442/2098
摘要： Adhesive articles that include a substrate, a silicone polyoxamide-containing primer layer, and a silicone adhesive are disclosed. Methods of making the adhesive articles and the use of a silicone polyoxamide as a primer for improving adhesion between a substrate and a silicone adhesive are also disclosed.
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8.发明公开
公开(公告)号：EP1765348A4
公开(公告)日：2010-05-26
申请号：EP05814989
申请日：2005-06-17
发明人： STOERMER DORIS , DELLARIA JOSEPH F JR , AMOS DAVID T , ZIMMERMANN BERNHARD M , DRESSEL LUKE T , BONK JASON D , RADMER MATTHEW R
IPC分类号： C07D471/14 , A61K31/437
CPC分类号： C07D471/04 , C07D471/14
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公开(公告)号：EP1687307A4
公开(公告)日：2009-06-17
申请号：EP04812098
申请日：2004-11-24
IPC分类号： C07D471/04 , A61K20060101 , A61K31/4745 , A61P37/00 , C07D213/74 , C07D221/00 , C07D235/00 , C07D471/02
CPC分类号： C07D471/04 , C07D213/74 , C07D255/02 , C07D471/14
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公开(公告)号：EP1685129A4
公开(公告)日：2008-10-22
申请号：EP04810872
申请日：2004-11-12
发明人： KSHIRSAGAR TUSHAR A , LUNDQUIST GREGORY D JR , AMOS DAVID T , DELLARIA JOSEPH F JR , ZIMMERMANN BERNHARD M , HEPPNER PHILIP D
IPC分类号： C07D471/02 , A61K20060101 , C07D471/06
CPC分类号： C07D471/04 , C07D471/14 , C07D519/00
摘要： Imidazo ring compounds (e.g., imidazoquinolines, 6,7,8,9-tetrahydroimidazoquinolines, imidazonaphthyridines, and imidazopyridines) with an oxime substituent at the 2-position, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
摘要翻译： 含有在2-位具有肟取代基的咪唑环化合物（例如咪唑并喹啉，6,7,8,9-四氢咪唑并喹啉，咪唑并萘啶和咪唑并吡啶），含有这些化合物作为免疫调节剂的化合物，中间体和方法的药物组合物 ，用于在动物中诱导细胞因子生物合成以及用于治疗包括病毒和肿瘤疾病的疾病。
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