公开(公告)号：EP0626177A2

公开(公告)日：1994-11-30

申请号：EP93114404.2

申请日：1993-09-08

申请人： ABBOTT LABORATORIES

发明人： Cope, Frederick Oliver ,  Dewille, Normanella Torres ,  Richards, Ernest William ,  Abbruzzese, Bonnie Chandler ,  Chandler, Michael Allen ,  Snowden, Gregory Allan ,  Mazer, Terrence Bruce

IPC分类号： A61K37/18 ,  A23L1/305 ,  A23L1/308 ,  A23L1/30 ,  A23J1/14

CPC分类号： A61K38/011 ,  A23L33/18 ,  A23L33/40 ,  A61K38/01 ,  A61K31/20 ,  A61K2300/00

摘要： An enteral nutritional product for persons infected with human immunodeficiency virus contains a soy protein hydrolysate having a molecular weight partition, as determined by size exclusion chromatography, wherein 30-60% of the particles have a molecular weight in the range of 1500-5000 Daltons. The nutritional product also contains a source of intact protein. The nutritional product has a ratio, by weight, of n-6 to n-3 fatty acids of about 1.3:1 to 2.5:1. Enteral nutritional support of a person infected with human immunodeficiency virus may be provided by including this enteral nutritional product in the infected person's diet. Apoptosis of CD4 cells in a person infected with human immunodeficiency virus may be impeded by feeding the infected person this enteral nutritional product.

摘要翻译： 针对感染人类免疫缺陷病毒的人的肠内营养产品含有具有分子量分配的大豆蛋白水解产物，其通过尺寸排阻层析测定，其中30-60％的颗粒具有在1500-5000道尔顿范围内的分子量。 营养产品还含有完整蛋白质的来源。 营养产品具有重量比为约1.3:1至2.5:1的n-6至n-3脂肪酸的比例。 可以通过将这种肠内营养产品包括在感染者的饮食中来提供感染人类免疫缺陷病毒的人的肠内营养支持。 感染人类免疫缺陷病毒的人体CD4细胞的凋亡可能通过向被感染者喂食肠内营养产品而受阻。

公开(公告)号：EP0626177B1

公开(公告)日：1999-12-01

申请号：EP93114404.2

申请日：1993-09-08

申请人： ABBOTT LABORATORIES

发明人： Cope, Frederick Oliver ,  Dewille, Normanella Torres ,  Richards, Ernest William ,  Abbruzzese, Bonnie Chandler ,  Chandler, Michael Allen ,  Snowden, Gregory Allan ,  Mazer, Terrence Bruce

IPC分类号： A61K38/01 ,  A23L1/305 ,  A23L1/308 ,  A23L1/30 ,  A23J1/14

CPC分类号： A61K38/011 ,  A23L33/18 ,  A23L33/40 ,  A61K38/01 ,  A61K31/20 ,  A61K2300/00

公开(公告)号：EP1415650A1

公开(公告)日：2004-05-06

申请号：EP03026561.5

申请日：1997-04-25

申请人： ABBOTT LABORATORIES

发明人： Abbruzzese, Bonnie Chandler ,  McCamish, Mark Anthony ,  Cope, Frederick Oliver ,  Demichele, Stephen Joseph

IPC分类号： A61K31/20

CPC分类号： A61K9/0029 ,  A23L33/12 ,  A23L33/16 ,  A23L33/175 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/202 ,  A61K31/70 ,  A61K47/12 ,  A61K47/183 ,  Y10S426/80 ,  Y10S426/801 ,  A23V2250/187 ,  A23V2250/1868 ,  A23V2250/708 ,  A23V2250/712 ,  A23V2250/1626 ,  A23V2250/5046 ,  A23V2250/211 ,  A23V2200/30 ,  A23V2200/308 ,  A23V2200/02

摘要： The present invention provides a liquid nutritional composition comprising at least 450 mg per liter of ω-3 fatty acids, wherein the weight ratio of ω-6 fatty acids to ω-3 fatty acids is from 0.1 to 3.0; at least 50 grams per liter of a source of amino-nitrogen, wherein 15 to 50% by weight of the amino-nitrogen is branched-chain amino acids, and wherein tryptophan is present in an amount less than 5.0% by weight of the total amino-nitrogen; and at least 1 gram per liter of an antioxidant system comprised of at least one nutrient selected from the group consisting of beta-carotene, vitamin C, vitamin E and selenium.

摘要翻译： 一种预防和治疗人类的恶病质和/或厌食症的方法包括每天内部给药（a）含有ω-6脂肪酸和至少450mg的ω-3脂肪酸的油混合物， 各脂肪酸的重量比为0.1〜3.0，（b）氨基氮源，其中15-50重量％的源中的氨基酸是支链氨基酸，和（c）抗氧化剂组分，其包含 至少一种选自β-胡萝卜素，维生素C，维生素E，硒的营养素; 至少（a）和（c）存在于液体营养基质中。

公开(公告)号：EP0626176B1

公开(公告)日：1999-11-17

申请号：EP93114403.4

申请日：1993-09-08

申请人： ABBOTT LABORATORIES

发明人： Cope, Frederick Oliver ,  Dewille, Normanella Torres ,  Richards, Ernest William ,  Abbruzzese, Bonnie Chandler ,  Parlet, Nickki Lynn ,  Mazer, Terrence Bruce ,  Snowden, Gregory Allan ,  Pease, Laura Ann

IPC分类号： A61K38/01 ,  A23L1/305 ,  A23L1/308 ,  A23L1/053 ,  A23L1/303 ,  A23J1/14

CPC分类号： A61K38/01 ,  A23J3/14 ,  A23J3/346 ,  A23L33/12 ,  A23L33/18 ,  A23L33/185 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A61K38/168 ,  A61K38/17 ,  A61K2300/00 ,  A23V2200/30 ,  A23V2250/022 ,  A23V2250/55 ,  A23V2300/34

公开(公告)号：EP0626177A3

公开(公告)日：1995-02-22

申请号：EP93114404.2

申请日：1993-09-08

申请人： ABBOTT LABORATORIES

发明人： Cope, Frederick Oliver ,  Dewille, Normanella Torres ,  Richards, Ernest William ,  Abbruzzese, Bonnie Chandler ,  Chandler, Michael Allen ,  Snowden, Gregory Allan ,  Mazer, Terrence Bruce

IPC分类号： A61K37/18 ,  A23L1/305 ,  A23L1/308 ,  A23L1/30 ,  A23J1/14

CPC分类号： A61K38/011 ,  A23L33/18 ,  A23L33/40 ,  A61K38/01 ,  A61K31/20 ,  A61K2300/00

摘要： An enteral nutritional product for persons infected with human immunodeficiency virus contains a soy protein hydrolysate having a molecular weight partition, as determined by size exclusion chromatography, wherein 30-60% of the particles have a molecular weight in the range of 1500-5000 Daltons. The nutritional product also contains a source of intact protein. The nutritional product has a ratio, by weight, of n-6 to n-3 fatty acids of about 1.3:1 to 2.5:1. Enteral nutritional support of a person infected with human immunodeficiency virus may be provided by including this enteral nutritional product in the infected person's diet. Apoptosis of CD4 cells in a person infected with human immunodeficiency virus may be impeded by feeding the infected person this enteral nutritional product.

公开(公告)号：EP0626176A3

公开(公告)日：1995-02-22

申请号：EP93114403.4

申请日：1993-09-08

申请人： ABBOTT LABORATORIES

发明人： Cope, Frederick Oliver ,  Dewille, Normanella Torres ,  Richards, Ernest William ,  Abbruzzese, Bonnie Chandler ,  Parlet, Nickki Lynn ,  Mazer, Terrence Bruce ,  Snowden, Gregory Allan ,  Pease, Laura Ann

IPC分类号： A61K37/18 ,  A23L1/305 ,  A23L1/308 ,  A23L1/053 ,  A23L1/303 ,  A23J1/14

CPC分类号： A61K38/01 ,  A23J3/14 ,  A23J3/346 ,  A23L33/12 ,  A23L33/18 ,  A23L33/185 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A61K38/168 ,  A61K38/17 ,  A61K2300/00 ,  A23V2200/30 ,  A23V2250/022 ,  A23V2250/55 ,  A23V2300/34

摘要： An enteral nutritional product has been formulated for persons who are currently undergoing radiation therapy and/or chemotherapy. The nutritional product has a protein system which includes a soy protein hydrolysate. The nutritional product is very low in folic acid, contains β-carotene, and has a ratio of n-6 to n-3 fatty acids that is in the range of about 1.3:1 to 2.5:1.

公开(公告)号：EP0626176A2

公开(公告)日：1994-11-30

申请号：EP93114403.4

申请日：1993-09-08

申请人： ABBOTT LABORATORIES

发明人： Cope, Frederick Oliver ,  Dewille, Normanella Torres ,  Richards, Ernest William ,  Abbruzzese, Bonnie Chandler ,  Parlet, Nickki Lynn ,  Mazer, Terrence Bruce ,  Snowden, Gregory Allan ,  Pease, Laura Ann

IPC分类号： A61K37/18 ,  A23L1/305 ,  A23L1/308 ,  A23L1/053 ,  A23L1/303 ,  A23J1/14

CPC分类号： A61K38/01 ,  A23J3/14 ,  A23J3/346 ,  A23L33/12 ,  A23L33/18 ,  A23L33/185 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A61K38/168 ,  A61K38/17 ,  A61K2300/00 ,  A23V2200/30 ,  A23V2250/022 ,  A23V2250/55 ,  A23V2300/34

摘要： An enteral nutritional product has been formulated for persons who are currently undergoing radiation therapy and/or chemotherapy. The nutritional product has a protein system which includes a soy protein hydrolysate. The nutritional product is very low in folic acid, contains β-carotene, and has a ratio of n-6 to n-3 fatty acids that is in the range of about 1.3:1 to 2.5:1.

摘要翻译： 目前正在进行放射治疗和/或化疗的人已经制定了肠内营养产品。 营养产品具有包括大豆蛋白水解产物的蛋白质系统。 营养产品在叶酸中非常低，含有β-胡萝卜素，并且n-6至n-3脂肪酸的比例在约1.3:1至2.5:1的范围内。