公开(公告)号：EP1380842A3

公开(公告)日：2009-12-30

申请号：EP03021136.1

申请日：1993-03-24

申请人： ABBOTT LABORATORIES

发明人： Clark, Frederic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J.III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A ,  Merriam, Richard A. ,  Walker, Donny Ray ,  McDowell, Douglas D. ,  Rumbaugh, William A. ,  Clemens, John M.

IPC分类号： G01N35/02

CPC分类号： G01N35/0095 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2300/042 ,  B01L2300/043 ,  B29C45/00 ,  B29K2995/0032 ,  B29L2023/22 ,  G01N21/03 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2035/00168 ,  G01N2035/00277 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

摘要： A test sample container assembly for loading a plurality of test samples onto a test sample carousel of an automated analytical system and an automated, continuous and random access analytical system containing such test sample container assembly and capable of simultaneously effecting multiple assays of a plurality of liquid samples are disclosed. The test sample container assembly comprises (i) a housing with two parallel curved sides, said sides having the same radius of curvature as the test sample carousel, (ii) a top shelf with at least two openings for receiving test sample containers, (iii) a bottom parallel to and spaced apart from the top shelf defining with the curved surfaces therebetween a cavity, and (iv) wherein said bottom portion and said curved surfaces define a cavity therebetween wherein the at least two openings provide a predefined vertical alignment and the test sample container openings are presented in a plane parallel with the plane of the assembly shelf.

公开(公告)号：EP1028320A3

公开(公告)日：2001-03-14

申请号：EP00108051.4

申请日：1994-09-22

申请人： ABBOTT LABORATORIES

发明人： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J. III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith B., Jane ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom Richard L. ,  Walker, Donny Ray ,  Watkins, William E. III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC分类号： G01N35/02

CPC分类号： G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

摘要： The present invention relates to a method of operating an automated, continuous and random access analytical system capable of simultaneously effecting multiple assays in a plurality of liquid samples, comprising the following steps: introducing sample cups, reagent packs, and reaction vessels for performing said assays onto concentric carousels of a front end carousel, the reaction vessels being introduced to an outer carousel; identifying the reagent packs and sample cups; scheduling the assays; aligning the sample cups and reagent packs with a reaction vessel at a kitting station by rotating the respective carousels; kitting a unit dose disposable in a reaction vessel having multiple independent open chambers in accordance with the scheduled assay by transfer of the sample from the sample cup to a reaction vessel chamber and transfer of specific reagents to separate reaction vessel chambers from the reagent pack; transferring the kitted reaction vessel to a process carousel which is maintained under controlled environment conditions; pipetting the sample and various reagents into a reaction well of the reaction vessel, the amounts of reagent, sequencing of transfer and time spacing therebetween being predetermined by assay scheduling; incubating the pipetted sample and reagent mix; identifying and transferring the incubated mixture in the reaction well to one of at least two assay analytical stations; performing an analysis by reading the prepared reaction mixture and calibrating the reading; and recording the resulting assay reading analysis.

公开(公告)号：EP1443329A3

公开(公告)日：2004-09-29

申请号：EP04010960.5

申请日：1994-09-22

申请人： Abbott Laboratories

发明人： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J. III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith, Jane B. ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom, Richard L. ,  Walker, Donny Ray ,  Watkins, William E. III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC分类号： G01N35/02 ,  G01N33/53

CPC分类号： G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

摘要： The present invention relates to a method for simultaneously performing at least two assays, said assays comprising a plurality of activities, for a plurality of liquid samples on a continuous analytical system, said method comprising the steps of: combining an aliquot of a first liquid sample with at least one reagent in a first reaction container to form a first assay reaction mixture for said first liquid sample; combining an aliquot of a second liquid sample with at least one reagent in a second reaction container to form a second assay reaction mixture for said second liquid sample; incubating said first and said second assay reaction mixtures at least one time; performing activities associated with each assay other than said combining and said incubating on the first and second assay reaction mixtures to complete each assay, said other activities including analyzing the incubated assay reaction mixtures; and scheduling the steps of said combining, said incubating, and said performing activities other than said combining and said incubating associated with each of the assays according to a predetermined protocol, said protocol specifying: (a) what activities are to be performed for a given assay; (b) an order in which said activities of (a) are to be performed; (c) at least one incubation period between said activities of (a), said at least one incubation period comprising a nominal period of time for the performance of an incubating step between activities of (a) and a specified window of time for varying the duration of the nominal period between activities of (a) to optimize performance; (d) how said activities of (a) are to be performed; and (e) duration of said activities of (a).

公开(公告)号：EP1380842A2

公开(公告)日：2004-01-14

申请号：EP03021136.1

申请日：1993-03-24

申请人： Abbott Laboratories

发明人： Clark, Frederic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J.III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A ,  Merriam, Richard A. ,  Walker, Donny Ray ,  McDowell, Douglas D. ,  Rumbaugh, William A. ,  Clemens, John M.

IPC分类号： G01N35/02

CPC分类号： G01N35/0095 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2300/042 ,  B01L2300/043 ,  B29C45/00 ,  B29K2995/0032 ,  B29L2023/22 ,  G01N21/03 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2035/00168 ,  G01N2035/00277 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

摘要： A test sample container assembly for loading a plurality of test samples onto a test sample carousel of an automated analytical system and an automated, continuous and random access analytical system containing such test sample container assembly and capable of simultaneously effecting multiple assays of a plurality of liquid samples are disclosed. The test sample container assembly comprises (i) a housing with two parallel curved sides, said sides having the same radius of curvature as the test sample carousel, (ii) a top shelf with at least two openings for receiving test sample containers, (iii) a bottom parallel to and spaced apart from the top shelf defining with the curved surfaces therebetween a cavity, and (iv) wherein said bottom portion and said curved surfaces define a cavity therebetween wherein the at least two openings provide a predefined vertical alignment and the test sample container openings are presented in a plane parallel with the plane of the assembly shelf.

摘要翻译： 一种用于将多个测试样品加载到自动分析系统的测试样品转盘上的测试样品容器组件和包含这种测试样品容器组件并且能够同时进行多种液体的多种测定的自动化，连续和随机存取分析系统 样品被公开。 测试样品容器组件包括（i）具有两个平行弯曲侧面的壳体，所述侧部具有与测试样品转盘相同的曲率半径，（ii）具有用于接收测试样品容器的至少两个开口的顶架，（iii ）平行于所述顶架的间隔开的底部，其间具有空腔之间的弯曲表面，以及（iv）其中所述底部部分和所述弯曲表面在其间限定了空腔，其中所述至少两个开口提供预定垂直对准，并且 测试样品容器开口呈现在与组装架平面平行的平面内。

公开(公告)号：EP1028320A2

公开(公告)日：2000-08-16

申请号：EP00108051.4

申请日：1994-09-22

申请人： ABBOTT LABORATORIES

发明人： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J. III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith B, Jane ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom Richard L. ,  Walker, Donny Ray ,  Watkins, William E. III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC分类号： G01N35/02

CPC分类号： G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

摘要： The present invention relates to a method of operating an automated, continuous and random access analytical system capable of simultaneously effecting multiple assays in a plurality of liquid samples, comprising the following steps: introducing sample cups, reagent packs, and reaction vessels for performing said assays onto concentric carousels of a front end carousel, the reaction vessels being introduced to an outer carousel; identifying the reagent packs and sample cups; scheduling the assays; aligning the sample cups and reagent packs with a reaction vessel at a kitting station by rotating the respective carousels; kitting a unit dose disposable in a reaction vessel having multiple independent open chambers in accordance with the scheduled assay by transfer of the sample from the sample cup to a reaction vessel chamber and transfer of specific reagents to separate reaction vessel chambers from the reagent pack; transferring the kitted reaction vessel to a process carousel which is maintained under controlled environment conditions; pipetting the sample and various reagents into a reaction well of the reaction vessel, the amounts of reagent, sequencing of transfer and time spacing therebetween being predetermined by assay scheduling; incubating the pipetted sample and reagent mix; identifying and transferring the incubated mixture in the reaction well to one of at least two assay analytical stations; performing an analysis by reading the prepared reaction mixture and calibrating the reading; and recording the resulting assay reading analysis.

摘要翻译： 本发明涉及的方法在自动化的，连续的和随机存取的分析能够同时 - 影响多个测定在液体样品的复数，包括以下步骤系统中操作：将样品杯，试剂包，并且反应容器用于进行所述测定 到前端转盘的同心旋转木马，反应容器被引入到在传送带外; 标识试剂袋和样品杯; 调度所述测定法; 通过旋转respectivement转盘对准样品杯和试剂袋与在备料站的反应容器; 备料的单位剂量在具有雅舞蹈多个独立的开放腔室与从所述样品杯的样品转移至反应容器腔室和特定的试剂从试剂包单独的反应容器室的传送被调度的测定的反应容器中一次性; 被控制的环境条件下保持转移环成套的反应容器中的处理转盘所有; 吸移样本和各种试剂到反应容器中的反应孔试剂，量，转移和时间通过测定调度被预先确定之间的间隔有的测序; 孵育所述移液样品和试剂混合物; 在反应识别和传递环保温的混合物以及至少两个化验分析站中的一个; 通过读取制备的反应混合物中，并校准读出执行的分析; 并记录所得到的测定读数的分析。

公开(公告)号：EP1443329A2

公开(公告)日：2004-08-04

申请号：EP04010960.5

申请日：1994-09-22

申请人： Abbott Laboratories

发明人： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J. III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith, Jane B. ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom, Richard L. ,  Walker, Donny Ray ,  Watkins, William E. III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC分类号： G01N35/02 ,  G01N33/53

CPC分类号： G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

摘要： The present invention relates to a method for simultaneously performing at least two assays, said assays comprising a plurality of activities, for a plurality of liquid samples on a continuous analytical system, said method comprising the steps of: combining an aliquot of a first liquid sample with at least one reagent in a first reaction container to form a first assay reaction mixture for said first liquid sample; combining an aliquot of a second liquid sample with at least one reagent in a second reaction container to form a second assay reaction mixture for said second liquid sample; incubating said first and said second assay reaction mixtures at least one time; performing activities associated with each assay other than said combining and said incubating on the first and second assay reaction mixtures to complete each assay, said other activities including analyzing the incubated assay reaction mixtures; and scheduling the steps of said combining, said incubating, and said performing activities other than said combining and said incubating associated with each of the assays according to a predetermined protocol, said protocol specifying: (a) what activities are to be performed for a given assay; (b) an order in which said activities of (a) are to be performed; (c) at least one incubation period between said activities of (a), said at least one incubation period comprising a nominal period of time for the performance of an incubating step between activities of (a) and a specified window of time for varying the duration of the nominal period between activities of (a) to optimize performance; (d) how said activities of (a) are to be performed; and (e) duration of said activities of (a).

摘要翻译： 本发明涉及一种用于同时进行至少两种测定的方法，所述测定法包括多个活性，对于连续分析系统上的多个液体样品，所述方法包括以下步骤：将等分试样的第一液体样品 与第一反应容器中的至少一种试剂形成用于所述第一液体样品的第一测定反应混合物; 将第二液体样品的等分试样与第二反应容器中的至少一种试剂组合以形成用于所述第二液体样品的第二测定反应混合物; 至少一次孵育所述第一和所述第二测定反应混合物; 执行与所述组合以外的每个测定相关的活动，并且在第一和第二测定反应混合物上孵育以完成每个测定，所述其它活性包括分析培养的测定反应混合物; 并且根据预定协议安排所述组合，所述孵育和所述执行活动之外的所述组合和所述孵化与每个测定相关联的步骤，所述协议规定：（a）将对给定的 法; （b）执行（a）的活动的命令; （c）所述活动之间的至少一个潜伏期（a），所述至少一个潜伏期包括在（a）的活动与指定的时间窗口之间执行孵化步骤的标称时间段，以改变 活动之间的名义期间的持续时间（a）优化业绩; （d）如何执行（a）的活动; （e）（a）所述活动的持续时间。

公开(公告)号：EP1380843A2

公开(公告)日：2004-01-14

申请号：EP03021137.9

申请日：1993-03-24

申请人： Abbott Laboratories

发明人： Clark, Frederic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J.III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A ,  Merriam, Richard A. ,  Walker, Donny Ray ,  McDowell, Douglas D. ,  Rumbaugh, William A. ,  Clemens, John M.

IPC分类号： G01N35/02

CPC分类号： G01N35/0095 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2300/042 ,  B01L2300/043 ,  B29C45/00 ,  B29K2995/0032 ,  B29L2023/22 ,  G01N21/03 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2035/00168 ,  G01N2035/00277 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

摘要： A liquid level sensing device for sensing the level of a liquid in a container and an automated, continuous and random access analytical system containing such liquid level sensing device and capable of simultaneously effecting multiple assays of a plurality of liquid samples are disclosed. The liquid level sensing device comprises: (a) means for producing an electrical sinusoidal signal; (b) means for evaluating the amount of signal as it propagates from a probe to a sense antenna; (c) circuit means for creating an electrical signal wherein said electrical signal changes when a probe contacts liquid; (d) signal processing means for enhancing the electrical signal and for degrading and suppressing signals not associated with the probe contacting said liquid; (e) decision circuit means for causing a basic digital output indicating either the presence or absence of liquid; and (f) means for utilizing the digital signal for controlling motion, and wherein said sensing device detects signal change and rate of signal change.

摘要翻译： 公开了一种用于感测容器中的液体水平的液面感测装置和包含这种液位感测装置并且能够同时进行多个液体样品的多次测定的自动连续和随机存取分析系统。 液位检测装置包括：（a）产生电正弦信号的装置; （b）用于在从探头传播到感测天线时评估信号量的装置; （c）用于产生电信号的电路装置，其中当探针接触液体时，所述电信号改变; （d）信号处理装置，用于增强电信号并降低和抑制与所述探头接触的所述液体不相关的信号; （e）用于使基本数字输出指示液体存在或不存在的判定电路装置; 和（f）用于利用数字信号来控制运动的装置，并且其中所述感测装置检测信号变化和信号变化率。

公开(公告)号：EP1205756A2

公开(公告)日：2002-05-15

申请号：EP02001046.8

申请日：1994-09-22

申请人： Abbott Laboratories

发明人： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J., III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith, Jane B. ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom, Richard L. ,  Walker, Donny Ray ,  Watkins, William E., III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC分类号： G01N35/10

CPC分类号： G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

摘要： The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.

摘要翻译： 本发明涉及一种用于检测容器中液体存在的自动液位传感系统，所述液位传感系统包括：位于所述容器上方的垂直取向的导电探头; 垂直移动所述探针进出所述容器的装置; 信号源，其电连接到所述探针，所述信号源用电信号激励所述探针并且使所述探针传送所述电信号; 位于所述容器下方的接收天线，用于接收所述发射的电信号; 用于分析所述接收到的电信号以用于指示所述探针已经接触所述容器中的液体的装置; 用于将所述接收的电信号从所述接收天线传送到所述分析装置的装置; 以及用于指示已检测到液体的装置。 此外，本发明还提供了一种用于自动检测容器中液体存在的方法，所述方法包括以下步骤：在所述容器上方垂直放置导电探针; 垂直移动所述探针进出所述容器; 将信号源电连接到所述探头，所述信号源用电信号激励所述探头并使所述探头传送所述电信号; 将接收天线定位在所述容器下方用于接收所述传输的电信号; 分析所述接收的电信号以指示所述探针已接触所述容器中的液体; 将所述接收的电信号从所述接收天线传送到所述分析装置; 并指示已检测到液体。

公开(公告)号：EP1443329B1

公开(公告)日：2010-09-15

申请号：EP04010960.5

申请日：1994-09-22

申请人： ABBOTT LABORATORIES

发明人： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J. III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith, Jane B. ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom, Richard L. ,  Walker, Donny Ray ,  Watkins, William E. III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC分类号： G01N35/02 ,  G01N33/53

CPC分类号： G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

公开(公告)号：EP1380844A2

公开(公告)日：2004-01-14

申请号：EP03021138.7

申请日：1993-03-24

申请人： Abbott Laboratories

发明人： Clark, Frederic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J.III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A ,  Merriam, Richard A. ,  Walker, Donny Ray ,  McDowell, Douglas D. ,  Rumbaugh, William A. ,  Clemens, John M.

IPC分类号： G01N35/02

CPC分类号： G01N35/0095 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2300/042 ,  B01L2300/043 ,  B29C45/00 ,  B29K2995/0032 ,  B29L2023/22 ,  G01N21/03 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2035/00168 ,  G01N2035/00277 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

摘要： A heater assembly for precision temperature and delivery control of liquids and an automated, continuous and random access analytical system containing such heater assembly and capable of simultaneously effecting multiple assays of a plurality of liquid samples are disclosed. The heater assembly comprises a body having internal resistance heating means and temperature control means, said body having a cavity suitable for accommodating liquid tubing means, said liquid tubing means in communication with liquid inlet and outlet means, wherein said cavity is suitable for housing a tubing means for maintaining liquids at a predetermined temperature, and wherein said liquid outlet means is suitable for forced or gravity release of the liquids and is mounted directly above analytical means for receiving liquids.

摘要翻译： 公开了一种用于液体的精确温度和输送控制的加热器组件和包含这种加热器组件并能够同时进行多个液体样品的多次测定的自动化，连续和随机存取分析系统。 加热器组件包括具有内部电阻加热装置和温度控制装置的主体，所述主体具有适于容纳液体管道装置的空腔，所述液体管道装置与液体入口和出口装置连通，其中所述腔体适于容纳管道 用于将液体保持在预定温度的装置，并且其中所述液体出口装置适于强制或重力地释放液体，并且直接安装在用于接收液体的分析装置上方。