专利检索 ap:("ABBOTT LABORATORIES") AND inv:"KOENIG, R. John" 第 1 页

1.

发明公开
CHROMANYLUREA COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR AND USES THEREOF 审中-公开
标题翻译： SUBTYP 1（VR1）受体的抑制香草素CHROMANYLHARNSTOFFVERBINDUNGEN及其用途

公开(公告)号：EP1844038A2

公开(公告)日：2007-10-17

申请号：EP05825417.8

申请日：2005-11-22

申请人： ABBOTT LABORATORIES

发明人： GOMTSYAN, Arthur, R. , BAYBURT, Erol, K. , SCHMIDT, Robert, G., Jr. , LEE, Chih-hung , BROWN, S. Brian , JINKERSON, K. Tammie , KOENIG, R. John , DAANEN, F. Jerome , LATSHAW, Steve

IPC分类号： C07D405/00

CPC分类号： C07D405/12 , C07D401/12 , C07D403/12 , C07D413/12

摘要： Compounds that are antagonists of the VR1 receptor, having formula (I) or a pharmaceutically acceptable salt, prodrug, or salt of a prodrug thereof, wherein A1, A2, A3, A4, R7, R8, R9, X, Y, Z, L, n, and m, are as defined herein, and are useful in disorders prevented or ameliorated by inhibiting the VR1 receptor.