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公开(公告)号:EP2114948A2
公开(公告)日:2009-11-11
申请号:EP07855102.5
申请日:2007-12-12
申请人: ABBOTT LABORATORIES
IPC分类号: C07D487/04 , C07D243/14 , C07D241/06 , C07D241/36 , A61K31/4188 , A61K31/4965 , A61K31/502 , A61K31/5513 , A61K31/5517
CPC分类号: C07D241/08 , C07D241/44 , C07D243/08 , C07D243/14 , C07D471/04 , C07D487/04
摘要: Inhibitors of poly(ADP-ribose)polymerase, ways to make them and methods of treating patients using them are disclosed.
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公开(公告)号:EP2021316A1
公开(公告)日:2009-02-11
申请号:EP07797725.4
申请日:2007-05-24
申请人: ABBOTT LABORATORIES
发明人: DIEBOLD, Robert B. , DJURIC, Stevan W. , GIRANDA, Vincent L , HEXAMER, Laura , LIN, Nan-horng , MIYASHIRO, Julie M. , PENNING, Thomas D. , PRZYTULINSKA, Magdalena , SOWIN, Thomas , SULLIVAN, Gerard , TAO, Zhi-fu , TONG, Yunsong , VASUDEVAN, Anil , WANG, Le , WOODS, Keith W. , XIA, Zhiren , ZHANG, Henry Q.
IPC分类号: C07C225/20 , C07D249/14 , C07D277/64 , C07D285/06 , C07D333/20 , A61P35/00 , A61K31/132 , A61K31/505
CPC分类号: C07D249/14 , C07C225/20 , C07C2601/02 , C07C2601/04 , C07D277/64 , C07D285/06 , C07D333/20
摘要: Compounds that inhibit Plk1, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
摘要翻译: 其中X1,C1和D1在本文中定义的式(I)化合物是polo样激酶的抑制剂。 式(I)化合物可用于治疗细胞增殖疾病,例如癌症。
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