专利检索 ap:("ABBOTT LABORATORIES") AND inv:"NERSESIAN, Diana L." 第 1 页

1.

发明公开
FUSED BICYCLOHETEROCYCLE SUBSTITUTED QUINUCLIDINE DERIVATIVES 审中-公开
标题翻译：用缩合的双环杂环取代的奎宁环衍生物

公开(公告)号：EP1824848A1

公开(公告)日：2007-08-29

申请号：EP04813737.6

申请日：2004-12-10

申请人： ABBOTT LABORATORIES

发明人： JI, Jianguo , LI, Tao , MORTELL, Kathleen H. , SCHRIMPF, Michael R. , NERSESIAN, Diana L. , PAN, Liping

IPC分类号： C07D453/02 , A61K31/439 , A61P25/28

CPC分类号： C07D453/02

摘要： Compounds of formula (I) wherein n is 0, 1, or 2; A is N or N+-O-; X is O, S, -NH-, and -N-alkyl-; Ar1 is a 6-membered aromatic ring; and Ar2 is a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by a7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.

2.

发明公开
INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF 审中-公开
标题翻译：吲哚和吲哚啉及其使用方法

公开(公告)号：EP2344505A2

公开(公告)日：2011-07-20

申请号：EP09793046.5

申请日：2009-09-28

申请人： Abbott Laboratories

发明人： SCHRIMPF, Michael R. , LEE, Chih-Hung , LI, Tao , GFESSER, Gregory A. , MORTELL, Kathleen H. , FAGHIH, Ramin , NERSESIAN, Diana L. , SIPPY, Kevin B. , BUNNELLE, William H. , SCANIO, Marc , SHI, Lei , GOPALAKRISHNAN, Murali , DONNELLY-ROBERTS, Diana , HU, Min

IPC分类号： C07D487/18 , A61K31/33 , A61P25/00

CPC分类号： G01N33/5058 , C07D471/18 , C07D487/10 , C07D487/18 , G01N33/6896 , G01N2800/28 , G01N2800/30

摘要： The present application relates to indole and indoline derivatives of formula (I), (II), (III), (IV), (V), or (VI) wherein a, R
1 , R
2 , R
3 , R
4 , R
5 , U, V, W, X, Y, and Z are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating disease conditions using such compounds and compositions, and methods for identifying such compounds.

3.

发明公开
AMIDE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS AND METHODS OF USE THEREOF 有权
标题翻译：酰胺衍生物为阳性变构调节剂及其使用方法

公开(公告)号：EP2250162A2

公开(公告)日：2010-11-17

申请号：EP09707625.1

申请日：2009-02-06

申请人： Abbott Laboratories

发明人： MORTELL, Kathleen H. , NERSESIAN, Diana L. , SCHRIMPF, Michael R. , LEE, Chih-Hung , GOPALAKRISHNAN, Murali

IPC分类号： C07D401/12

CPC分类号： C07D401/12 , C07D209/08 , C07D403/12 , C07D471/04

摘要： The invention relates to novel amide derivatives that are PAMs of neuronal nicotinic receptors, compositions comprising the same, processes for preparing such compounds, and methods for using such compounds and compositions.