公开(公告)号：EP0815203B1

公开(公告)日：2011-09-28

申请号：EP96908794.9

申请日：1996-03-13

申请人： ABT Holding Company ,  North Shore University Hospital

发明人： GRANDE, Daniel, A. ,  LUCAS, Paul, A.

IPC分类号： C12N5/00

CPC分类号： A61L27/3834 ,  A61F2/30756 ,  A61K35/12 ,  A61K35/34 ,  A61K35/36 ,  A61L27/3847 ,  A61L27/3852 ,  A61L2430/02 ,  A61L2430/06 ,  C12N5/0668 ,  C12N2533/40

摘要： It has been discovered that mesenchymal stem cells (MSCs) in a polymeric carrier implanted into a cartilage and/or bone defect will differentiate to form cartilage and/or bone, as appropriate. Suitable polymeric carriers include porous meshes or sponges formed of synthetic or natural polymers, as well as polymer solutions. A presently preferred material is a polyglycolic acid mesh.

公开(公告)号：EP0815203A1

公开(公告)日：1998-01-07

申请号：EP96908794.0

申请日：1996-03-13

申请人： Morphogen Pharmaceuticals, Inc. ,  North Shore University Hospital

发明人： GRANDE, Daniel, A. ,  LUCAS, Paul, A.

IPC分类号： A61F2 ,  A61K35 ,  A61L27 ,  C12N5

CPC分类号： A61L27/3834 ,  A61F2/30756 ,  A61K35/12 ,  A61K35/34 ,  A61K35/36 ,  A61L27/3847 ,  A61L27/3852 ,  A61L2430/02 ,  A61L2430/06 ,  C12N5/0668 ,  C12N2533/40

摘要： It has been discovered that mesenchymal stem cells (MSCs) in a polymeric carrier implanted into a cartilage and/or bone defect will differentiate to form cartilage and/or bone, as appropriate. Suitable polymeric carriers include porous meshes or sponges formed of synthetic or natural polymers, as well as polymer solutions. A presently preferred material is a polyglycolic acid mesh.