公开(公告)号：EP2214017A4

公开(公告)日：2010-12-29

申请号：EP08842461

申请日：2008-10-22

申请人： ALFRESA PHARMA CORP ,  NOF CORP

发明人： YANAGIYA MARI ,  TANAKA MUTSUMI ,  KOSAKA MIEKO ,  ENOMOTO MASAYASU ,  YAMADA SATOSHI ,  NAKASHIMA FUMIO

IPC分类号： G01N33/53 ,  G01N33/531 ,  G01N33/543 ,  G01N33/545 ,  G01N33/553 ,  G01N33/577

CPC分类号： G01N33/5308 ,  G01N33/54313

公开(公告)号：EP3193171A4

公开(公告)日：2018-04-11

申请号：EP15840489

申请日：2015-09-08

申请人： NOF CORP

发明人： NAKASHIMA FUMIO ,  YAMADA SATOSHI ,  NODA TOMOZUMI ,  MATSUDA MASARU

IPC分类号： G01N33/531 ,  C07F9/09

CPC分类号： G01N33/15 ,  C07F9/09 ,  C07F9/10 ,  G01N33/531

摘要： There is provided a protein adsorption inhibitor comprising a compound represented by Formula (1) as an active ingredient. The protein adsorption inhibitor is capable of highly inhibiting non-specific adsorption of a protein such as an antibody or an enzyme to a surface of a base body such as an immune reaction vessel or an assay instrument. There is further provided a coating layer-formed base body having a coating layer containing the protein adsorption inhibitor on the base body. The coating layer-formed base body has an excellent protein adsorption-inhibiting function. There is still further provided a method for inhibiting the adsorption of the protein to the base body comprising forming the coating layer containing the protein adsorption inhibitor on the surface of the base body. In Formula (1), X is a hydrogen atom or a methyl group and n is an integer of 9 to 15.

公开(公告)号：EP3178927A4

公开(公告)日：2018-02-28

申请号：EP15830388

申请日：2015-08-06

申请人： NOF CORP

发明人： NAKASHIMA FUMIO ,  MATSUDA MASARU ,  NODA TOMOZUMI ,  YAMADA SATOSHI

IPC分类号： C07F9/09 ,  C07F9/10 ,  C12N9/16 ,  C12N9/96 ,  G01N33/68

CPC分类号： C12N9/96 ,  C07F9/091 ,  C07F9/10 ,  C12N9/16 ,  C12Y301/03001 ,  G01N33/68

摘要： There is provided a protein stabilizer containing a compound represented by Formula (1) as an active ingredient. The protein stabilizer is capable of stabilizing a protein in a solution state for a long period of time without affecting an assay system, the protein being not limited to enzymes, labeling substances such as fluorescent substances and chemiluminescent substances, and assay target substances. There is also provided a protein stabilization method containing making the protein coexist with the compound represented by Formula (1) in a water-containing solution. In Formula (1), X is a hydrogen atom or a methyl group, and n is an integer of 3 to 17.

公开(公告)号：EP3260862A4

公开(公告)日：2018-08-01

申请号：EP16752538

申请日：2016-02-18

申请人： NATIONAL UNIV CORPORATION KYOTO INSTITUTE OF TECHNOLOGY ,  NOF CORP

发明人： KUMADA YOICHI ,  KAWAGUCHI YASUTAKA ,  NEMOTO ARANNA ,  NAKASHIMA FUMIO ,  SAKAMOTO NOBUYUKI

IPC分类号： G01N33/48

CPC分类号： G01N33/48 ,  C07F9/4461 ,  C08F220/56 ,  C08F222/385

摘要： Provided is a novel method of suppressing non-specific protein adsorption. The above-mentioned object can be achieved by treating a solid phase with a solid phase-treating liquid containing a phosphorylcholine group-containing polymer as a main component, and treating a specimen with a specimen-treating liquid containing, as a main component, a polymer having a phosphorylcholine group, a hydroxy group, and a hydrophobic group, followed by addition of the treated specimen to the treated solid phase.

公开(公告)号：EP3216856A4

公开(公告)日：2018-07-18

申请号：EP15856806

申请日：2015-10-30

申请人： NOF CORP

发明人： NODA TOMOZUMI ,  NAKASHIMA FUMIO ,  YAMADA SATOSHI ,  SAKAMOTO NOBUYUKI

IPC分类号： C12M3/00 ,  C12N5/071 ,  C12N5/0735

CPC分类号： C12M23/20 ,  B05D7/22 ,  C12M21/08 ,  C12N5/0606

摘要： An object is to provide a method of manufacturing a vessel for embryoid body formation excellent in formability of an embryoid body and suitable for optical observation.