公开(公告)号：EP2437784B1

公开(公告)日：2013-10-30

申请号：EP10722756.3

申请日：2010-06-03

申请人： ALGIPHARMA AS

发明人： ONSØYEN, Edvar ,  MYRVOLD, Rolf ,  DESSEN, Arne ,  THOMAS, David ,  WALSH, Timothy

IPC分类号： A61K47/36

CPC分类号： A61K31/734 ,  A01N37/18 ,  A01N43/22 ,  A01N43/60 ,  A01N43/72 ,  A01N43/78 ,  A01N43/86 ,  A01N43/90 ,  A61K31/407 ,  A61K31/427 ,  A61K31/496 ,  A61K31/546 ,  A61K31/65 ,  A61K31/7028 ,  A61K31/7048 ,  A61K31/7052 ,  A61K45/06 ,  Y02A50/473 ,  A61K2300/00

摘要： The invention provides a method to improve the efficacy of an antibiotic to inhibit the growth of Acinetobacter, said method comprising using said antibiotic together with an alginate oligomer. The Acinetobacter may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides an alginate oligomer for use together with at least one antibiotic in treating a subject infected, suspected to be infected, or at risk of infection, with Acinetobacter. In another aspect the method can be used to combat Acinetobacter contamination of a site e.g., for disinfection and cleaning purposes.

公开(公告)号：EP2437784B8

公开(公告)日：2013-12-11

申请号：EP10722756.3

申请日：2010-06-03

申请人： ALGIPHARMA AS

发明人： ONSØYEN, Edvar ,  MYRVOLD, Rolf ,  DESSEN, Arne ,  THOMAS, David ,  WALSH, Timothy

IPC分类号： A61K47/36

CPC分类号： A61K31/734 ,  A01N37/18 ,  A01N43/22 ,  A01N43/60 ,  A01N43/72 ,  A01N43/78 ,  A01N43/86 ,  A01N43/90 ,  A61K31/407 ,  A61K31/427 ,  A61K31/496 ,  A61K31/546 ,  A61K31/65 ,  A61K31/7028 ,  A61K31/7048 ,  A61K31/7052 ,  A61K45/06 ,  Y02A50/473 ,  A61K2300/00

摘要： The invention provides a method to improve the efficacy of an antibiotic to inhibit the growth of Acinetobacter, said method comprising using said antibiotic together with an alginate oligomer. The Acinetobacter may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides an alginate oligomer for use together with at least one antibiotic in treating a subject infected, suspected to be infected, or at risk of infection, with Acinetobacter. In another aspect the method can be used to combat Acinetobacter contamination of a site e.g., for disinfection and cleaning purposes.

公开(公告)号：EP2437784A1

公开(公告)日：2012-04-11

申请号：EP10722756.3

申请日：2010-06-03

申请人： ALGIPHARMA AS

发明人： ONSØYEN, Edvar ,  MYRVOLD, Rolf ,  DESSEN, Arne ,  THOMAS, David ,  WALSH, Timothy

IPC分类号： A61K47/36

CPC分类号： A61K31/734 ,  A01N37/18 ,  A01N43/22 ,  A01N43/60 ,  A01N43/72 ,  A01N43/78 ,  A01N43/86 ,  A01N43/90 ,  A61K31/407 ,  A61K31/427 ,  A61K31/496 ,  A61K31/546 ,  A61K31/65 ,  A61K31/7028 ,  A61K31/7048 ,  A61K31/7052 ,  A61K45/06 ,  Y02A50/473 ,  A61K2300/00

摘要： The invention provides a method to improve the efficacy of an antibiotic to inhibit the growth of Acinetobacter, said method comprising using said antibiotic together with an alginate oligomer. The Acinetobacter may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides an alginate oligomer for use together with at least one antibiotic in treating a subject infected, suspected to be infected, or at risk of infection, with Acinetobacter. In another aspect the method can be used to combat Acinetobacter contamination of a site e.g., for disinfection and cleaning purposes.

公开(公告)号：EP2755481B1

公开(公告)日：2020-03-18

申请号：EP12766466.2

申请日：2012-09-14

申请人： ALGIPHARMA AS

发明人： ONSØYEN, Edvar ,  DESSEN, Arne ,  THOMAS, David William ,  HILL, Katja Etel ,  SLETTA, Håvard ,  TØNDERVIK, Anne ,  KLINKENBERG, Geir ,  MYRVOLD, Rolf

IPC分类号： A01N43/16 ,  A61K31/734 ,  A01N43/90 ,  A01N43/653 ,  A01P3/00

公开(公告)号：EP2755481A1

公开(公告)日：2014-07-23

申请号：EP12766466.2

申请日：2012-09-14

申请人： ALGIPHARMA AS

发明人： ONSØYEN, Edvar ,  DESSEN, Arne ,  THOMAS, David William ,  HILL, Katja Etel ,  SLETTA, Håvard ,  TØNDERVIK, Anne ,  KLINKENBERG, Geir ,  MYRVOLD, Rolf

IPC分类号： A01N43/16 ,  A61K31/734 ,  A01N43/90 ,  A01N43/653 ,  A01P3/00

摘要： The disclosure relates to use of alginate oligomers to enhance the effects of antifungal agents. The invention provides a method to improve the efficacy of an antifungal agent against a fungus, said method comprising using said antifungal agent together with an alginate oligomer. The fungus may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides an alginate oligomer for use together with at least one antifungal agent in treating a subject infected, suspected to be infected, or at risk of infection, with a fungus. In another aspect the method can be used to combat fungal contamination of a site e.g., for disinfection and cleaning purposes.

摘要翻译： 本公开涉及使用藻酸盐低聚物来增强抗真菌剂的作用。 本发明提供了一种提高抗真菌剂对真菌的功效的方法，所述方法包括将所述抗真菌剂与藻酸盐低聚物一起使用。 真菌可以是生物或无生命的表面，并提供医疗和非医疗用途和方法。 在一个方面，本发明提供了一种与至少一种抗真菌剂一起使用的藻酸盐低聚物，以用真菌治疗被感染的，疑似感染的或有感染风险的受试者。 在另一方面，该方法可用于抵抗现场的真菌污染，例如用于消毒和清洁目的。