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公开(公告)号：EP1670796A1
公开(公告)日：2006-06-21
申请号：EP04787262.7
申请日：2004-09-30
申请人： ALTANA Pharma AG
发明人： ULRICH, Wolf-Ruediger , FUCHSS, Thomas , MARTIN, Thomas , BOER, Rainer , STRUB, Andreas , ELTZE, Manfrid , LEHNER, Martin
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00 , C07D519/00
CPC分类号： C07D471/04
摘要： The compounds of formula (I) in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors.
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公开(公告)号：EP1673371A1
公开(公告)日：2006-06-28
申请号：EP04787261.9
申请日：2004-09-30
申请人： ALTANA Pharma AG
发明人： ULRICH, Wolf-Ruediger , FUCHSS, Thomas , MARTIN, Thomas , BOER, Rainer , STRUB, Andreas , ELTZE, Manfrid , LEHNER, Martin , MARX, Degenhard
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00
CPC分类号： C07D471/04
摘要： The compounds of formula (I) in which R1, R2, Het1 and A have the meanings as given in the description are novel effective iNOS inhibitors.
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公开(公告)号：EP1675854A1
公开(公告)日：2006-07-05
申请号：EP04787263.5
申请日：2004-09-30
申请人： ALTANA Pharma AG
发明人： ULRICH, Wolf-Ruediger , FUCHSS, Thomas , MARTIN, Thomas , BOER, Rainer , STRUB, Andreas , ELTZE, Manfrid , LEHNER, Martin
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00
CPC分类号： C07D471/04 , A61K31/437
摘要： The compounds of formula (I) in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors.
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公开(公告)号：EP1670798A1
公开(公告)日：2006-06-21
申请号：EP04820599.1
申请日：2004-09-30
申请人： Altana Pharma AG
发明人： FUCHSS, Thomas , BOER, Rainer , MARX, Degenhard , ULRICH, Wolf-Ruediger , ELTZE, Manfrid , NAVE, Ruediger , STRUB, Andreas , GRAEDLER, Ulrich
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00
CPC分类号： C07D471/04
摘要： The compounds of formula (I) in which R1, R2, R3 and R4 the meanings as given in the description are novel effective iNOS inhibitors.
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公开(公告)号：EP1490366A1
公开(公告)日：2004-12-29
申请号：EP03744851.1
申请日：2003-03-25
申请人： ALTANA Pharma AG
发明人： ULRICH, Wolf-Rüdiger , BOER, Rainer , MARX, Degenhard , ELTZE, Manfrid , KLEIN, Thomas , NAVE, Rüdiger , GRÄDLER, Ulrich , FUCH , Thomas , BARSIG, Johannes
IPC分类号： C07D471/04 , C07D473/00 , A61K31/4427 , A61K31/52 , A61P25/00
CPC分类号： C07D471/04 , C07D473/00
摘要： The compounds of formula (I) in which R1 is 1-4C-alkoxy, , A is 1-4C-alkylene, B represents 3H-imidazo (4,5b) pyridin-2-yl, 3H-imidazo (4,5-b) pyridin-2-yl substituted by R2 and/or R8, 9H-purin-8yl or 9H-purin-8-yl substituted by R4 and/or R5 are effective iNOS inhibitors.
摘要翻译： 其中R1是1-4C-烷氧基，A是1-4C-亚烷基，B代表3H-咪唑并（4,5b）吡啶-2-基，3H-咪唑并（4,5- b）由R 2和/或R 8取代的吡啶-2-基，由R 4和/或R 5取代的9H-嘌呤-8基或9H-嘌呤-8-基是有效的iNOS抑制剂。
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6.发明授权IMIDAZO 4,5-B QUINOLINE-DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS 有权IMIDAZO¬4,5-B |喹啉及其作为抑制剂诱导型NO合酶
公开(公告)号：EP1599473B1
公开(公告)日：2006-09-20
申请号：EP04713907.6
申请日：2004-02-24
申请人： ALTANA Pharma AG
IPC分类号： C07D471/04 , A61K31/47
CPC分类号： C07D471/04
摘要： The compounds of formula I In which R1, R2, R3 and A have the meanings as given In the description are novel effective INOS Inhibitors.
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7.发明公开IMIDAZO(4,5-B)PYRIDINE-DERIVATIVES AS INDUCIBLE NO-SYNTHASE INHIBITORS 有权咪唑并[4,5-b]吡啶衍生物作为可诱导的NO合酶的抑制剂
公开(公告)号：EP1675853A1
公开(公告)日：2006-07-05
申请号：EP04787257.7
申请日：2004-09-30
申请人： ALTANA Pharma AG
发明人： FUCHSS, Thomas , BOER, Rainer , ULRICH, Wolf-Ruediger , ELTZE, Manfrid , MARX, Degenhard , GRAEDLER, Ulrich
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00
CPC分类号： C07D471/04
摘要： The compounds of formula (I) in which R1, R2, R3, R4 and R11 the meanings as given in the description are novel effective iNOS inhibitors.
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8.发明公开IMIDAZO 4,5-B QUINOLINE-DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS 有权咪唑并[4,5-B]喹啉衍生物和它们作为抑制剂的诱导型NO合成酶使用
公开(公告)号：EP1599473A1
公开(公告)日：2005-11-30
申请号：EP04713907.6
申请日：2004-02-24
申请人： ALTANA Pharma AG
IPC分类号： C07D471/04 , A61K31/47
CPC分类号： C07D471/04
摘要： The compounds of formula I In which R1, R2, R3 and A have the meanings as given In the description are novel effective INOS Inhibitors.
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