-
1.发明公开
公开(公告)号：EP1763526A1
公开(公告)日：2007-03-21
申请号：EP05769611.4
申请日：2005-06-28
申请人： Altana Pharma AG
发明人： STADLWIESER, Josef , BAER, Thomas , MAIER, Thomas , BECKERS, Thomas , CIOSSEK, Thomas , ZUELCH, Armin , GRAEDLER, Ulrich , WIRSCHUN, Wolfgang , HERDEMANN, Matthias
IPC分类号： C07D405/04 , A61K31/506 , A61P35/00
CPC分类号： C07D405/04 , C07D239/42 , C07D401/04 , C07D405/14 , C07D409/04
摘要： The invention relates to novel pyrimidine derivatives of Formula (I), which are efficacious inhibitors of protein kinases, in particular of one or more isoforms of the protein kinase B/Akt.
-
公开(公告)号：EP1670798A1
公开(公告)日：2006-06-21
申请号：EP04820599.1
申请日：2004-09-30
申请人： Altana Pharma AG
发明人： FUCHSS, Thomas , BOER, Rainer , MARX, Degenhard , ULRICH, Wolf-Ruediger , ELTZE, Manfrid , NAVE, Ruediger , STRUB, Andreas , GRAEDLER, Ulrich
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00
CPC分类号： C07D471/04
摘要： The compounds of formula (I) in which R1, R2, R3 and R4 the meanings as given in the description are novel effective iNOS inhibitors.
-
公开(公告)号：EP1641457A1
公开(公告)日：2006-04-05
申请号：EP04741933.8
申请日：2004-06-30
申请人： ALTANA Pharma AG
IPC分类号： A61K31/4745 , A61P25/00 , A61P35/00
CPC分类号： A61K31/4745
摘要： The invention relates to the use of a pyrrolo `2,1-a! isoquinoline structure-element as an integral part of the overall structure of compounds, which inhibit PDE10.
-
4.发明授权IMIDAZO 4,5-B QUINOLINE-DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS 有权IMIDAZO¬4,5-B |喹啉及其作为抑制剂诱导型NO合酶
公开(公告)号：EP1599473B1
公开(公告)日：2006-09-20
申请号：EP04713907.6
申请日：2004-02-24
申请人： ALTANA Pharma AG
IPC分类号： C07D471/04 , A61K31/47
CPC分类号： C07D471/04
摘要： The compounds of formula I In which R1, R2, R3 and A have the meanings as given In the description are novel effective INOS Inhibitors.
-
5.发明公开IMIDAZO(4,5-B)PYRIDINE-DERIVATIVES AS INDUCIBLE NO-SYNTHASE INHIBITORS 有权咪唑并[4,5-b]吡啶衍生物作为可诱导的NO合酶的抑制剂
公开(公告)号：EP1675853A1
公开(公告)日：2006-07-05
申请号：EP04787257.7
申请日：2004-09-30
申请人： ALTANA Pharma AG
发明人： FUCHSS, Thomas , BOER, Rainer , ULRICH, Wolf-Ruediger , ELTZE, Manfrid , MARX, Degenhard , GRAEDLER, Ulrich
IPC分类号： C07D471/04 , A61K31/437 , A61K31/444 , A61P25/00 , A61P29/00 , A61P31/00
CPC分类号： C07D471/04
摘要： The compounds of formula (I) in which R1, R2, R3, R4 and R11 the meanings as given in the description are novel effective iNOS inhibitors.
-
6.发明公开IMIDAZO 4,5-B QUINOLINE-DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS 有权咪唑并[4,5-B]喹啉衍生物和它们作为抑制剂的诱导型NO合成酶使用
公开(公告)号：EP1599473A1
公开(公告)日：2005-11-30
申请号：EP04713907.6
申请日：2004-02-24
申请人： ALTANA Pharma AG
IPC分类号： C07D471/04 , A61K31/47
CPC分类号： C07D471/04
摘要： The compounds of formula I In which R1, R2, R3 and A have the meanings as given In the description are novel effective INOS Inhibitors.
-
7.发明公开N-4-(6-(HETEO)ARYL-PYRIMIDIN-4-YLAMINOPHENYL)-BENZENESULFONAMIDES AS KINASE INHIBITORS 审中-公开N-4-（6-（HETEO）ARYLPYRIMIDIN-4-YLAMINOPHENYL）苯二甲酰胺ALS激酶基因
公开(公告)号：EP1709007A1
公开(公告)日：2006-10-11
申请号：EP05701549.7
申请日：2005-01-19
申请人： Altana Pharma AG
发明人： BARSIG, Johannes , BAUDLER, Monika , BUNDSCHUH, Daniela , GANTNER, Florian , GRAEDLER, Ulrich , HEIT, Isabelle , MARTIN, Thomas , SCHAEFER, Michaela , SCHLEMMINGER, Imre , STADLWIESER, Josef , ULRICH, Wolf-Ruediger
IPC分类号： C07D239/42 , C07D409/14 , C07D403/04 , C07D405/04 , A61K31/505 , A61K31/506 , A61P35/00 , A61P37/00
CPC分类号： C07D239/42 , C07D403/04 , C07D405/04 , C07D409/14
摘要： Compounds of a certain formula 1 in which R1 and R2 have the meanings indicated in the description are novel kinase inhibitors. Formula (1), in which R1 is phenyl, phenyl substituted by R3 and/or R4, naphthalenyl, naphthalenyl substituted by R5 and/or R6, aryl1, aryl1 substituted by R7 and/or R8, R9, R10 or R11, R2 is phenyl, phenyl substituted by R12 and/or R13, naphthalenyl, naphthalenyl substituted by R14 and/or R15, aryl2, aryl2 substituted by R16 and/or R17 or a radical selected from Formula (2).
-
公开(公告)号：EP1641792A1
公开(公告)日：2006-04-05
申请号：EP04741932.0
申请日：2004-06-30
申请人： ALTANA Pharma AG
发明人： VENNEMANN, Matthias , BAER, Thomas , BRAUNGER, Juergen , MAIER, Thomas , GRAEDLER, Ulrich , GIMMNICH, Petra , QUINTINI, Gianluca , CIAPETTI, Paola , CONTRERAS, Jean-Marie , WERMUTH, Camille Georges
IPC分类号： C07D471/04 , A61K31/4745 , A61P25/00 , A61P15/00 , A61P3/10
CPC分类号： C07D471/04 , A61K31/4745
摘要： The invention relates to novel pyrrolodihydroisoquinoline derivatives, which are efficacious inhibitors of PDE10.
摘要翻译： 本发明涉及新的吡咯并二氢异喹啉衍生物，其是PDE10的有效抑制剂。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.014 秒)
