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公开(公告)号：EP1791847A2
公开(公告)日：2007-06-06
申请号：EP05787333.3
申请日：2005-09-05
申请人： Altana Pharma AG
发明人： FLOCKERZI, Dieter , KAUTZ, Ulrich , HATZELMANN, Armin , ZITT, Christof , WOHLSEN, Andrea , MARX, Degenhard , KLEY, Hans-Peter , CHRISTOFFERS, Jens , ROSIAK, Anna
IPC分类号： C07D498/06
CPC分类号： C07D495/04
摘要： Compounds of a certain formula 1, in which A, R1, R2 and R3 have the meanings indicated in the de- scription, are novel effective PDE4 inhibitors.
摘要翻译： 其中A，R1，R2和R3具有说明中所示含义的某些式1化合物是新型有效的PDE4抑制剂。
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2.发明授权
公开(公告)号：EP1539164B1
公开(公告)日：2006-12-20
申请号：EP03790931.4
申请日：2003-08-28
申请人： ALTANA Pharma AG
发明人： KAUTZ, Ulrich , SCHMIDT, Beate , FLOCKERZI, Dieter , GRUNDLER, Gerhard , NAVE, Rüdiger , HUMMEL, Rolf-Peter , STURM, Ernst , HATZELMANN, Armin , BARSIG, Johannes , MARX, Degenhard , KLEY, Hans-PETER
IPC分类号： A61K31/473 , C07D221/12 , A61P11/08
CPC分类号： C07D221/12
摘要： Compounds of a certain formula I, in which R1, R2, R3, R31, R4, R5, R6 and R7 have the meanings indicated in the desription, are novel effective PDE4 inhibitors.
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3.发明公开NOVEL DIFLUOROETHOXY-SUBSTITUTED HYDROXY-6-PHENYLPHENANTHRIDINES AND THEIR USE AS PDE4 INHIBITORS 审中-公开新型二氟乙氧基取代的羟基-6-苯基苯并噻吩类化合物及其作为PDE4抑制剂的用途
公开(公告)号：EP1725532A1
公开(公告)日：2006-11-29
申请号：EP05716950.0
申请日：2005-03-08
申请人： Altana Pharma AG
发明人： KAUTZ, Ulrich , SCHMIDT, Beate , FLOCKERZI, Dieter , HATZELMANN, Armin , ZITT, Christof , BARSIG, Johannes , MARX, Degenhard , KLEY, Hans-Peter
IPC分类号： C07D221/12 , A61K31/473
CPC分类号： C07D221/12
摘要： Compounds of a certain formula (I), in which R1, R2, R3, R31, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective PDE4 inhibitors.
摘要翻译： 其中R 1，R 2，R 3，R 31，R 4，R 5，R 6和R 7具有说明书中所示含义的某些式（I）化合物是新的有效PDE4抑制剂。
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4.发明授权
公开(公告)号：EP1147088B1
公开(公告)日：2006-01-04
申请号：EP00901530.6
申请日：2000-01-12
申请人： ALTANA Pharma AG
发明人： FLOCKERZI, Dieter , AMSCHLER, Hermann DI , GRUNDLER, Gerhard , HATZELMANN, Armin , BUNDSCHUH, Daniela , BEUME, Rolf , BOSS, Hildegard , GOEBEL, Karl-Josef , KLEY, Hans-Peter , SCHMIDT, Beate
IPC分类号： C07D221/12 , A61K31/435 , A61P11/08 , C07D401/04 , C07D405/04
CPC分类号： C07D401/04 , C07D221/12 , C07D401/12 , C07D405/04 , C07D409/04 , C07D491/04
摘要： Compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51 and Ar have the meanings indicated in the description, are novel active bronchial therapeutics.
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公开(公告)号：EP1539164A1
公开(公告)日：2005-06-15
申请号：EP03790931.4
申请日：2003-08-28
申请人： ALTANA Pharma AG
发明人： KAUTZ, Ulrich , SCHMIDT, Beate , FLOCKERZI, Dieter , GRUNDLER, Gerhard , NAVE, Rüdiger , HUMMEL, Rolf-Peter , STURM, Ernst , HATZELMANN, Armin , BARSIG, Johannes , MARX, Degenhard , KLEY, Hans-PETER
IPC分类号： A61K31/473 , C07D221/12 , A61P11/08
CPC分类号： C07D221/12
摘要： Compounds of a certain formula I, in which R1, R2, R3, R31, R4, R5, R6 and R7 have the meanings indicated in the desription, are novel effective PDE4 inhibitors.
摘要翻译： 其中R 1，R 2，R 3，R 31，R 4，R 5，R 6和R 7具有描述中所示含义的某些式I化合物是新型有效PDE4抑制剂。
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6.发明公开PYRROLIDINEDIONE SUBSTITUTED PIPERIDINE-PHTHALAZONES AS PDE4 INHIBITORS 有权吡咯烷取代的哌啶PHTHALAZONE作为PDE4抑制剂的
公开(公告)号：EP1537100A1
公开(公告)日：2005-06-08
申请号：EP03792257.2
申请日：2003-08-06
申请人： ALTANA Pharma AG
发明人： STERK, Geert, Jan , HATZELMANN, Armin , BARSIG, Johannes , MARX, Degenhard , KLEY, Hans-Peter , CHRISTIAANS, Johannes, A., M. , MENGE, Wiro, M., P., B.
IPC分类号： C07D401/14 , A61K31/502 , A61P11/00
CPC分类号： C07D401/04 , A61K31/50 , A61K31/502 , C07D401/14 , C07D405/14
摘要： The compounds of a certain formula (1), in which the given substituents have the meanings as indicated in the description, are novel effective PDE4 inhibitors.
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公开(公告)号：EP1147087B1
公开(公告)日：2005-05-11
申请号：EP00901089.3
申请日：2000-01-12
申请人： ALTANA Pharma AG
发明人： FLOCKERZI, Dieter , AMSCHLER, Hermann DI , HATZELMANN, Armin , BUNDSCHUH, Daniela , BEUME, Rolf , BOSS, Hildegard , KLEY, Hans-Peter , GUTTERER, Beate
IPC分类号： C07D221/12 , A61K31/435 , A61P11/08
CPC分类号： C07D221/12
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公开(公告)号：EP0920426B9
公开(公告)日：2005-04-06
申请号：EP97940080.1
申请日：1997-08-13
申请人： ALTANA Pharma AG
发明人： AMSCHLER, Hermann , MARTIN, Thomas , FLOCKERZI, Dieter , Schmidt, Beate , THIBAUT, Ulrich , HATZELMANN, Armin , BOSS, Hildegard , HÄFNER, Dietrich , KLEY, Hans-Peter , BEUME, Rolf , BÄR, Thomas , ULRICH, Wolf-Rüdiger
IPC分类号： C07D401/14 , A61K31/425
CPC分类号： C07D417/04 , C07D417/14
摘要： Compounds having the formula (I), in which R1, R2, R3, R4 and n have the meanings given in the description, are new effective bronchotherapeutic agents (phosphodiesterase IV inhibitors).
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公开(公告)号：EP1070056B1
公开(公告)日：2004-06-30
申请号：EP99914474.4
申请日：1999-03-04
申请人： ALTANA Pharma AG
发明人： HATZELMANN, Armin , BOSS, Hildegard , HÄFNER, Dietrich , BEUME, Rolf , KLEY, Hans-Peter , VAN DER LAAN, Ivonne, Johanna , TIMMERMAN, Hendrik , STERK, Geert, Jan , VAN DER MEY, Margaretha
IPC分类号： C07D237/32 , A61K31/50 , C07D417/12 , A61K31/54
CPC分类号： C07D237/32 , C07D417/12
摘要： The compounds of formula (I) in which R1, R2, R3, R4, R5, X and Y have the meanings as given in the description are novel effective bronchial therapeutica.
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10.发明公开COMPOUNDS EFFECTIVE AS BETA-2-ADRENORECEPTOR AGONISTS AS WELL AS PDE4-INHIBITORS 审中-公开ALSβ-2肾上腺素受体激动剂和ALS PDE4抑制剂起作用的化合物
公开(公告)号：EP1296956A1
公开(公告)日：2003-04-02
申请号：EP01936419.9
申请日：2001-06-01
申请人： ALTANA Pharma AG , Byk Nederland BV
发明人： HATZELMANN, Armin , BUNDSCHUH, Daniela , ELTZE, Manfrid , VAN DER LAAN, Yvonne , TIMMERMANN, Hendrik , CHRISTIAANS, Johannes , BRUNDEL, Paulus , STERK, Geert
IPC分类号： C07D237/14 , C07D237/22 , C07D237/32 , C07D405/04 , A61K31/50 , A61K31/501 , A61K31/502 , A61P11/06
CPC分类号： C07D401/04 , C07D237/32 , C07D405/04
摘要： The compounds of formula I in which Ar1, A, R6, R7, R8 and Ar2 have the meanings as given in the description are novel effective bronchial therapeutics.
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