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公开(公告)号：EP1131055B1
公开(公告)日：2005-11-09
申请号：EP99971701.0
申请日：1999-11-09
申请人： ALTANA Pharma AG
CPC分类号： A61K38/1709 , A61K9/0082
摘要： The invention describes a set for the treatment of IRDS, ALI or ARDS, comprising a first container which has a volume of 50 to 500 ml and contains a pulverulent pulmonary surfactant preparation, the amount of phospholipids in the container being 50 to 500 mg, and a second container which has a volume of 50 to 500 ml and contains a pulverulent pulmonary surfactant preparation, where the amount of phospholipids in the second container is 1 to 10 g.
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公开(公告)号：EP1095040B1
公开(公告)日：2004-03-31
申请号：EP99931198.8
申请日：1999-06-26
申请人： ALTANA Pharma AG
发明人： ULRICH, Wolf-Rüdiger , AMSCHLER, Hermann , BÄR, Thomas , FLOCKERZI, Dieter , SCHMIDT, Beate , THIBAUT, Ulrich , HATZELMANN, Armin , BOSS, Hildegard , BEUME, Rolf , KLEY, Hans-Peter , HÄFNER, Dietrich , MARTIN, Thomas
IPC分类号： C07D413/04 , C07D263/56 , A61K31/42
CPC分类号： C07D263/56 , C07D413/04
摘要： Compounds of formula (I) in which R1, R2, R3 and A have the meanings indicated in the description, are novel efficacious PDE inhibitors.
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3.发明公开NOVEL USE OF PULMONARY SURFACTANT FOR THE PROPHYLAXIS OR EARLY TREATMENT OF ACUTE PULMONARY DISEASES 有权FOR THE预防和早期治疗急性肺疾病肺表面活性物质的新用途
公开(公告)号：EP1276495A1
公开(公告)日：2003-01-22
申请号：EP01943250.9
申请日：2001-04-12
申请人： ALTANA Pharma AG
发明人： HÄFNER, Dietrich , KELLER, Andreas , RATHGEB, Frank , SCHAFFER, Peter , WURST, Wilhelm , KARL, Christoph
CPC分类号： A61K38/1709
摘要： The invention describes the novel use of pulmonary surfactant preparations for the prophylaxis or early treatment of acute pulmonary diseases.
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公开(公告)号：EP1000034B1
公开(公告)日：2002-09-18
申请号：EP98942571.5
申请日：1998-07-18
申请人： ALTANA Pharma AG
发明人： AMSCHLER, Hermann , FLOCKERZI, Dieter , ULRICH, Wolf-Rüdiger , BÄR, Thomas , MARTIN, Thomas , SCHUDT, Christian , HATZELMANN, Armin , BEUME, Rolf , HÄFNER, Dietrich , BOSS, Hildegard , KLEY, Hans-Peter , GUTTERER, Beate
IPC分类号： C07D221/12 , A61K31/435 , C07D491/04
CPC分类号： C07D491/04 , C07D221/12
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公开(公告)号：EP0920426B9
公开(公告)日：2005-04-06
申请号：EP97940080.1
申请日：1997-08-13
申请人： ALTANA Pharma AG
发明人： AMSCHLER, Hermann , MARTIN, Thomas , FLOCKERZI, Dieter , Schmidt, Beate , THIBAUT, Ulrich , HATZELMANN, Armin , BOSS, Hildegard , HÄFNER, Dietrich , KLEY, Hans-Peter , BEUME, Rolf , BÄR, Thomas , ULRICH, Wolf-Rüdiger
IPC分类号： C07D401/14 , A61K31/425
CPC分类号： C07D417/04 , C07D417/14
摘要： Compounds having the formula (I), in which R1, R2, R3, R4 and n have the meanings given in the description, are new effective bronchotherapeutic agents (phosphodiesterase IV inhibitors).
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公开(公告)号：EP1070056B1
公开(公告)日：2004-06-30
申请号：EP99914474.4
申请日：1999-03-04
申请人： ALTANA Pharma AG
发明人： HATZELMANN, Armin , BOSS, Hildegard , HÄFNER, Dietrich , BEUME, Rolf , KLEY, Hans-Peter , VAN DER LAAN, Ivonne, Johanna , TIMMERMAN, Hendrik , STERK, Geert, Jan , VAN DER MEY, Margaretha
IPC分类号： C07D237/32 , A61K31/50 , C07D417/12 , A61K31/54
CPC分类号： C07D237/32 , C07D417/12
摘要： The compounds of formula (I) in which R1, R2, R3, R4, R5, X and Y have the meanings as given in the description are novel effective bronchial therapeutica.
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公开(公告)号：EP0937074B1
公开(公告)日：2003-03-12
申请号：EP97950093.1
申请日：1997-11-05
申请人： ALTANA Pharma AG
发明人： SCHMIDT, Beate , AMSCHLER, Hermann , ULRICH, Wolf-Rüdiger , MARTIN, Thomas , BÄR, Thomas , HATZELMANN, Armin , SANDERS, Karl , BEUME, Rolf , BOSS, Hildegard , HÄFNER, Dietrich , KLEY, Hans-Peter , GOEBEL, Karl-Josef , FLOCKERZI, Dieter
IPC分类号： C07D471/04 , A61K31/47
CPC分类号： C07D471/04
摘要： Compounds of formula (I) in which R1, R2, R3 and R4 have the meanings indicated in the description, are novel active bronchial therapeutics.
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8.发明授权COMPOSITIONS COMPRISING PHENYLAMINOTHIOPHENACETIC ACID DERIVATIVES FOR THE TREATMENT OF ACUTE OR ADULT RESPIRATORY DISTRESS SYNDROME (ARDS) AND INFANT RESPIRATORY DISTRESS SYNDROME (IRDS) 有权制备含PHENYLAMINOTHIOPHENESSIGSÄURE的衍生物对急性呼吸功能不全（ARDS）和急性呼吸功能不全IN儿童的治疗（IRDS）
公开(公告)号：EP1098645B1
公开(公告)日：2002-11-20
申请号：EP99931116.0
申请日：1999-06-19
申请人： ALTANA Pharma AG
IPC分类号： A61K31/381 , A61P11/00
CPC分类号： A61K31/38
摘要： Novel compositions for the treatment of IRDS and ARDS are indicated which contain a compound of formula (I), in which R1 is hydrogen or 2-(2-hydroxyethoxy)ethyl and/or a pharmacologically tolerable salt of this compound and lung surfactant.
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公开(公告)号：EP1042319B1
公开(公告)日：2004-02-04
申请号：EP98966288.7
申请日：1998-12-10
申请人： ALTANA Pharma AG
发明人： THIBAUT, Ulrich , HATZELMANN, Armin , BOSS, Hildegard , HÄFNER, Dietrich , BEUME, Rolf , KLEY, Hans-Peter , TIMMERMAN, Hendrik , VAN DER LAAN, Ivonne, Johanna , ULRICH, Wolf-Rüdiger , STERK, Geert, Jan , VAN DER MEY, Margaretha
IPC分类号： C07D407/04 , A61K31/50
CPC分类号： C07D407/04
摘要： Compounds of formula (I), wherein R1, R2, R3 and Het have the meanings as given in the description are novel effective bronchial-therapeutics.
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公开(公告)号：EP0920426B1
公开(公告)日：2003-10-01
申请号：EP97940080.1
申请日：1997-08-13
申请人： ALTANA Pharma AG
发明人： AMSCHLER, Hermann , MARTIN, Thomas , FLOCKERZI, Dieter , Schmidt, Beate , THIBAUT, Ulrich , HATZELMANN, Armin , BOSS, Hildegard , HÄFNER, Dietrich , KLEY, Hans-Peter , BEUME, Rolf , BÄR, Thomas , ULRICH, Wolf-Rüdiger
IPC分类号： C07D401/14 , A61K31/425
CPC分类号： C07D417/04 , C07D417/14
摘要： Compounds having the formula (I), in which R1, R2, R3, R4 and n have the meanings given in the description, are new effective bronchotherapeutic agents (phosphodiesterase IV inhibitors).
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