专利检索 ap:("ALTANA Pharma AG") AND inv:"MELCHERS, Klaus" 第 1 页

1.

发明授权
RECOMBINANT SP-A FOR THE TREATMENT OR PREVENTION OF PULMONARY INFECTION AND INFLAMMATION 有权
标题翻译：重组SP-A用于治疗和预防肺部感染和炎症

公开(公告)号：EP1173194B1

公开(公告)日：2004-06-16

申请号：EP00912431.4

申请日：2000-01-18

申请人： ALTANA Pharma AG

发明人： MELCHERS, Klaus , SCHÄFER, Klaus, P. , STEINHILBER, Wolfram , WHITSETT, Jeffrey, A. , LEVINE, Ann, Marie , KORFHAGEN, Thomas, R.

IPC分类号： A61K38/17 , A61P11/00 , A61P31/04 , A61P31/10 , A61P31/12

CPC分类号： C07K14/785 , A61K38/00 , A61K38/1709 , Y10S514/885

摘要： Recombinant surfactant protein A and medicament compositions based thereon are useful for the prevention or treatment of pulmonary infection and inflammation.

2.

发明授权
SYNTHETISCHE PEPTIDANALOGE DES LUNGENOBERFLÄCHENPROTEINS SP-C 失效
标题翻译：合成肽模拟肺表面蛋白SP-C的

公开(公告)号：EP0764172B1

公开(公告)日：2004-09-01

申请号：EP95920906.5

申请日：1995-05-27

申请人： ALTANA Pharma AG

发明人： NAVE, Rüdiger , ULRICH, Wolf-Rüdiger , STURM, Ernst , KRÜGER, Uwe , HÄFNER, Dietrich , SCHÄFER, Klaus, P. , MELCHERS, Klaus

IPC分类号： C07K14/785 , A61K38/17

CPC分类号： C07K14/785 , A61K38/00

摘要： The disclosure concerns novel polypeptides of formula (I) with lung activity properties. These polypeptides can be produced in large quantities and in highly pure form and are as effective as natural lung surfactants. They can be used in the production of pharmaceutical composition for the treatment of respiratory distress syndrome in premature babies and adults. In said formula (I): A represents H or Phe, B represents Phe or Trp, and C represents Ile, Leu or Ser.