-
公开(公告)号：EP2342223A4
公开(公告)日：2013-01-23
申请号：EP09816953
申请日：2009-09-25
申请人： AMBRX INC , LILLY CO ELI
发明人： TIAN FENG , HAYS PUTNAM ANNA-MARIA A , SONG FRANK , CHU STEPHANIE , SHEFFER JOSEPH , BARNETT RICHARD S , SILADI MARC , ATKINSON KYLE , LEE DARIN , CANNING PETER C
CPC分类号： C07K14/505 , A61K38/00 , A61K38/1816 , A61K47/60 , C12N15/102
-
公开(公告)号：EP2069396A4
公开(公告)日：2009-10-28
申请号：EP07837882
申请日：2007-09-07
申请人： AMBRX INC
发明人： SHEFFER JOSEPH , NORMAN THEA , DIMARCHI RICHARD D , PUTNAM ANNA-MARIA A HAYS , FENG TIAN , CHU STEPHANIE , KRAWITZ DENISE , CHO HO SUNG
IPC分类号： C07K14/435 , C07K14/765 , C07K16/42 , C07K16/46
CPC分类号： C07K14/47 , A61K38/00 , C07K14/765 , C07K19/00 , C07K2319/00
-
公开(公告)号：EP2061878A4
公开(公告)日：2009-10-28
申请号：EP07837971
申请日：2007-09-07
申请人： AMBRX INC
发明人： TIAN FENG , NORMAN THEA , CHU STEPHANIE
摘要： This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in vertebrate cells. The components include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNA's/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in vertebrate cells are also provided. The present invention provides vertebrate cells with translation components, e.g., pairs of orthogonal aminoacyl-tRNA synthetases (O-RSs) and orthogonal tRNA's (O-tRNA's) and individual components thereof, that are used in vertebrate protein biosynthetic machinery to incorporate an unnatural amino acid in a growing polypeptide chain, in a vertebrate cell.
-
4.发明公开SITE SPECIFIC INCORPORATION OF NON-NATURAL AMINO ACIDS BY VERTEBRATE CELLS 有权位置特定INCORPORATION非天然氨基酸插入涡动物细胞
公开(公告)号：EP2064316A4
公开(公告)日：2009-09-30
申请号：EP07837970
申请日：2007-09-07
申请人： AMBRX INC
发明人： TIAN FENG , NORMAN THEA , CHU STEPHANIE
IPC分类号： C12N5/02
-
-
-
-
搜索结果
5 条记录 (耗时 0.007 秒)
