公开(公告)号：EP1171439A1

公开(公告)日：2002-01-16

申请号：EP00923540.9

申请日：2000-04-20

申请人： AMERICAN HOME PRODUCTS CORPORATION

发明人： MEWSHAW, Richard Eric ,  MEAGHER, Kristin Lynne

IPC分类号： C07D471/04 ,  A61K31/437 ,  A61P25/24

CPC分类号： C07D471/04

摘要： Compounds useful in the treatment of diseases affected by disorders of the serotonin-affected neurological systems, such as depression and anxiety, are provided having formula (I) wherein: R1 and R2 form a carbocyclic or heterocyclic ring of 5 to 7 atoms, wherein said ring may be saturated or unsaturated; and X is independently hydrogen, cyano, carbamoyl, halogen or alkoxy; or pharmaceutically acceptable salts thereof.

公开(公告)号：EP1171434A1

公开(公告)日：2002-01-16

申请号：EP00926187.6

申请日：2000-04-20

申请人： AMERICAN HOME PRODUCTS CORPORATION

发明人： MEWSHAW, Richard Eric ,  MEAGHER, Kristin Lynne

IPC分类号： C07D401/06 ,  C07D401/08 ,  A61K31/4725 ,  A61P25/24

CPC分类号： C07D401/06 ,  C07D401/08

摘要： Compounds are provided which have formula (I) wherein: R1, R2, R3, and R4 are, independently, hydrogen, halogen, alkoxy, or carboxamide; R5 is hydrogen, halogen, CF3, CN, carbamide or alkoxy; and X is (CH2)n or a 4-6 membered carbocyclic ring, wherein n is an integer of 2 to 4; or pharmaceutically acceptable salts thereof.