专利检索 ap:("Abbott GmbH & Co. KG") AND inv:"HUTCHINS, Charles W." 第 1 页

1.

发明公开
TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY 有权
标题翻译：啉，药物组合物阶及其治疗用途

公开(公告)号：EP2271625A2

公开(公告)日：2011-01-12

申请号：EP09727055.7

申请日：2009-03-31

申请人： Abbott GmbH & Co. KG , Abbott Laboratories

发明人： AMBERG, Wilhelm , OCHSE, Michael , LANGE, Udo , BRAJE, Wilfried , BEHL, Berthold , HORNBERGER, Wilfried , MEZLER, Mario , HUTCHINS, Charles W.

IPC分类号： C07D217/18 , C07D401/06 , C07D401/12 , C07D409/14 , C07D413/12 , C07D498/04 , C07D513/04 , A61K31/472 , A61P25/28

CPC分类号： C07D217/18 , C07D401/04 , C07D401/06 , C07D401/08 , C07D401/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D498/04 , C07D513/04

摘要： The present invention relates to tetrahydroisoquinoline of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such tetrahydroisoquinolines, and the use of such tetrahydroisoquinolines for therapeutic purposes. The tetrahydroisoquinolines are GIyT1 inhibitors.

2.

发明授权
TETRAHYDROISOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY 有权
标题翻译：啉，药物组合物阶及其治疗用途

公开(公告)号：EP2271625B1

公开(公告)日：2012-09-12

申请号：EP09727055.7

申请日：2009-03-31

申请人： Abbott GmbH & Co. KG , Abbott Laboratories

发明人： AMBERG, Wilhelm , OCHSE, Michael , LANGE, Udo , BRAJE, Wilfried , BEHL, Berthold , HORNBERGER, Wilfried , MEZLER, Mario , HUTCHINS, Charles W.

IPC分类号： C07D217/18 , C07D401/06 , C07D401/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D498/04 , C07D513/04 , A61K31/472 , A61P25/28

CPC分类号： C07D217/18 , C07D401/04 , C07D401/06 , C07D401/08 , C07D401/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D498/04 , C07D513/04

3.

发明公开
4-BENZYLAMINOQUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE 审中-公开
标题翻译： 4- BENZYLAMINOCHINOLINE，药物组合物含有，其使用

公开(公告)号：EP2178842A2

公开(公告)日：2010-04-28

申请号：EP08787409.5

申请日：2008-08-22

申请人： Abbott GmbH & Co. KG

发明人： AMBERG, Wilhelm , OCHSE, Michael , BRAJE, Wilfried , BEHL, Berthold , HORNBERGER, Wilfried , MEZLER, Mario , HUTCHINS, Charles W.

IPC分类号： C07D215/42 , C07D215/46 , C07D401/04 , C07D401/12 , C07D401/14 , A61K31/4706 , A61K31/4709 , A61P25/00

CPC分类号： C07D215/42 , C07D215/46 , C07D401/12 , C07D401/14

摘要： The present invention relates to 4-benzylaminoquinolines of the formula (I) or physiologically tolerated salts thereof. The invention relates to pharmaceutical compositions comprising such quinolines, and the use of such quinolines for therapeutic purposes. The quinolines are GIyTI inhibitors.