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1.发明授权NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS 失效新苯并-1,3-二唑和取代的苯并呋喃PYRROLIDINEDERIVATE ALS内皮素拮抗剂
公开(公告)号：EP0885215B1
公开(公告)日：2006-04-19
申请号：EP97905816.1
申请日：1997-02-12
申请人： ABBOTT LABORATORIES
发明人： WINN, Martin , BOYD, Steven, A. , HUTCHINS, Charles, W. , JAE, Hwan-Soo , TASKER, Andrew, S. , VON GELDERN, Thomas, W. , KESTER, Jeffrey, A. , SORENSEN, Bryan, K. , SZCZEPANKIEWICZ, Bruce, G. , HENRY, Kenneth, J., Jr. , LIU, Gang , WITTENBERGER, Steven, J. , KING, Steven, A.
IPC分类号： C07D405/04 , C07D207/16 , A61K31/40 , C07D405/14 , C07F9/59 , C07F9/572 , C07D401/04
CPC分类号： C07D401/04 , C07D207/16 , C07D405/04 , C07D405/12 , C07D405/14 , Y02P20/55
摘要： A compound of formula (I), or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
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2.发明公开NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS 失效新苯并-1,3-二唑和取代的苯并呋喃PYRROLIDINEDERIVATE ALS内皮素拮抗剂
公开(公告)号：EP0885215A1
公开(公告)日：1998-12-23
申请号：EP97905816.0
申请日：1997-02-12
申请人： Abbott Laboratories
发明人： WINN, Martin , BOYD, Steven, A. , HUTCHINS, Charles, W. , JAE, Hwan-Soo , TASKER, Andrew, S. , VON GELDERN, Thomas, W. , KESTER, Jeffrey, A. , SORENSEN, Bryan, K. , SZCZEPANKIEWICZ, Bruce, G. , HENRY, Kenneth, J., Jr. , LIU, Gang , WITTENBERGER, Steven, J. , KING, Steven, A.
IPC分类号： A61K31 , A61P1 , A61P7 , A61P9 , A61P11 , A61P13 , A61P25 , A61P43 , C07D207 , C07D211 , C07D401 , C07D403 , C07D405 , C07D409 , C07D413 , C07D417 , C07D419 , C07D453 , C07D471 , C07D491 , C07F9
CPC分类号： C07D401/04 , C07D207/16 , C07D405/04 , C07D405/12 , C07D405/14 , Y02P20/55
摘要： A compound of formula (I), or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
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