公开(公告)号：EP1080199A2

公开(公告)日：2001-03-07

申请号：EP99921120.4

申请日：1999-05-19

申请人： Abic Ltd.

发明人： PITKOVSKI, Jacob ,  MUALEM, Margalit ,  REI KOREN, Ziv ,  KRISPEL, Simcha ,  SHMUELI, Esther ,  PERETZ, Yifat ,  GUTTER, Bezalel ,  GALLILI, Gilad ,  MICHAEL, Amnon ,  GOLDBERG, Doron

IPC分类号： C12N15/34 ,  C12N15/62 ,  C12N15/86 ,  C12N5/10 ,  C12N7/00 ,  C07K14/075 ,  C07K16/08 ,  A61K31/70 ,  A61K39/235 ,  A61K48/00

CPC分类号： C12N15/86 ,  A61K39/00 ,  A61K48/00 ,  A61K49/00 ,  A61K2039/51 ,  A61K2039/5256 ,  C12N2710/10222 ,  C12N2710/10243

摘要： The present invention relates to a DNA sequence comprising a nucleotide sequence encoding Hemorrhagic Enteritis virus. It is well known to the man of the art that determining the complete sequence of a virus enables the isolation and identification of the different genes contained therein, and their utilisation for different purposes such as for vaccination purposes, as potential vectors for gene delivery to be used in recombinant vaccination or for gene therapy. In addition, the sequence may be employed for diagnostic purposes wherein the disclosed sequence of any part thereof be used for the development of specific primers for Polymerase Chain Reaction processes (PCR) or as probes. The invention thus also concerns with HEV proteins encoded by the sequence of the invention or functional fragments thereof and to some of the uses of said sequences and proteins.