公开(公告)号：EP2076124A2

公开(公告)日：2009-07-08

申请号：EP08746483.0

申请日：2008-04-21

申请人： Acucela, Inc.

发明人： SCOTT, Ian, Leslie ,  KUKSA, Vladimir, Aleksandrovich ,  GALL, Anna ,  ORME, Mark, W. ,  GAGE, Jennifer ,  LITTLE, Thomas, L., Jr. ,  JIANG, Qin ,  ROSSITER, Lana, Michele ,  MCGEE, Kevin, F., Jr. ,  KUBOTA, Ryo

IPC分类号： A01N33/02 ,  A61K31/135

CPC分类号： A61K31/5375 ,  A61K31/137 ,  A61K31/145 ,  A61K31/167 ,  A61K31/40 ,  A61K31/4453 ,  A61K31/495 ,  C07C211/27 ,  C07C211/28 ,  C07C211/29 ,  C07C215/08 ,  C07C215/30 ,  C07C215/42 ,  C07C215/46 ,  C07C217/10 ,  C07C217/16 ,  C07C217/18 ,  C07C217/48 ,  C07C217/54 ,  C07C217/62 ,  C07C217/72 ,  C07C225/06 ,  C07C225/18 ,  C07C233/05 ,  C07C237/04 ,  C07C317/28 ,  C07C323/25 ,  C07C323/32 ,  C07C323/33 ,  C07C2602/14 ,  C07C2602/16 ,  C07D207/06 ,  C07D211/14 ,  C07D295/03

摘要： The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.