公开(公告)号：EP2298890A1

公开(公告)日：2011-03-23

申请号：EP10012422.1

申请日：2005-12-28

申请人： Agency for Science, Technology and Research

发明人： Wong, Chee Furng ,  Yap, Miranda Gek Sim

IPC分类号： C12N15/10 ,  C12N15/63 ,  C07K14/47 ,  C07K14/57 ,  A01K67/027 ,  A61K38/00 ,  A61K48/00

CPC分类号： C07K14/4747

摘要： We provide an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence being selected from a FAIM sequence shown as SEQ ID NO: 1; a FADD sequence shown as SEQ ID NO: 2; a PDCD6 sequence shown as SEQ ID NO: 3; and a Requiem sequence shown as SEQ ID NO: 4.

公开(公告)号：EP2298887A1

公开(公告)日：2011-03-23

申请号：EP10012419.7

申请日：2005-12-28

申请人： Agency for Science, Technology and Research

发明人： Wong, Chee Furng ,  Yap, Miranda Gek Sim

IPC分类号： C12N15/10 ,  C12N15/63 ,  C07K14/47 ,  C07K14/57 ,  A01K67/027 ,  A61K38/00 ,  A61K48/00

CPC分类号： C07K14/4747

摘要： We provide an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence being selected from a FAIM sequence shown as SEQ ID NO: 1; a FADD sequence shown as SEQ ID NO: 2; a PDCD6 sequence shown as SEQ ID NO: 3; and a Requiem sequence shown as SEQ ID NO: 4.

摘要翻译： 我们提供了一种分离的多肽，其包含能够介导细胞凋亡的克鲁斯灰藓序列，所述序列选自如SEQ ID NO：1所示的FAIM序列; 如SEQ ID NO：2所示的FADD序列; 如SEQ ID NO：3所示的PDCD6序列; 和如SEQ ID NO：4所示的安魂曲序列。

公开(公告)号：EP1997890A1

公开(公告)日：2008-12-03

申请号：EP08014674.9

申请日：2005-12-28

申请人： Agency for Science, Technology and Research

发明人： Wong, Chee Furng ,  Yap, Miranda Gek Sim

IPC分类号： C12N15/10 ,  C12N15/63 ,  C07K14/47 ,  C07K14/57 ,  A01K67/027 ,  A61K38/00 ,  A61K48/00

CPC分类号： C07K14/4747

摘要： We provide an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence comprising a Requiem sequence having at least 90% sequence identity with a sequence shown in SEQ ID NO: 4 which polypeptide is capable of mediating apoptosis of a cell.

摘要翻译： 我们提供了一种分离的多肽，其包含能够介导细胞凋亡的克鲁斯灰藓序列，所述序列包含与SEQ ID NO：4所示的序列具有至少90％序列同一性的Requiem序列，该多肽能够介导细胞凋亡 细胞。

公开(公告)号：EP2298889A1

公开(公告)日：2011-03-23

申请号：EP10012421.3

申请日：2005-12-28

申请人： Agency for Science, Technology and Research

发明人： Wong, Chee Furng ,  Yap, Miranda Gek Sim

IPC分类号： C12N15/10 ,  C12N15/63 ,  C07K14/47 ,  C07K14/57 ,  A01K67/027 ,  A61K38/00 ,  A61K48/00

CPC分类号： C07K14/4747

摘要： We provide an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence being selected from a FAIM sequence shown as SEQ ID NO: 1; a FADD sequence shown as SEQ ID NO: 2; a PDCD6 sequence shown as SEQ ID NO: 3; and a Requiem sequence shown as SEQ ID NO: 4.

公开(公告)号：EP2298888A1

公开(公告)日：2011-03-23

申请号：EP10012420.5

申请日：2005-12-28

申请人： Agency for Science, Technology and Research

发明人： Wong, Chee Furng ,  Yap, Miranda Gek Sim

IPC分类号： C12N15/10 ,  C12N15/63 ,  C07K14/47 ,  C07K14/57 ,  A01K67/027 ,  A61K38/00 ,  A61K48/00

CPC分类号： C07K14/4747

摘要： We provide an isolated polypeptide comprising a Cricetulus griseus sequence capable of mediating apoptosis of a cell, the sequence being selected from a FAIM sequence shown as SEQ ID NO: 1; a FADD sequence shown as SEQ ID NO: 2; a PDCD6 sequence shown as SEQ ID NO: 3; and a Requiem sequence shown as SEQ ID NO: 4.

摘要翻译： 我们提供了包含能够介导细胞凋亡的灰仓鼠序列的分离的多肽，该序列选自SEQ ID NO：1所示的FAIM序列; 显示为SEQ ID NO：2的FADD序列; 显示为SEQ ID NO：3的PDCD6序列; 和SEQ ID NO：4所示的安瓿序列。