公开(公告)号：EP3079733B1

公开(公告)日：2018-05-30

申请号：EP14824277.9

申请日：2014-12-12

申请人： Agnovos Healthcare, LLC

发明人： MOSELEY, Jon ,  MACDOUGALL, Jamie ,  HARRIGAN, Katie

IPC分类号： A61L27/12 ,  A61L24/02 ,  C04B35/447

CPC分类号： A61L27/12 ,  A61L24/0015 ,  A61L24/02 ,  A61L27/025 ,  A61L27/3608 ,  A61L27/3641 ,  A61L27/3821 ,  A61L27/3847 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/10 ,  A61L2300/102 ,  A61L2300/112 ,  A61L2300/414 ,  A61L2400/06 ,  A61L2430/02 ,  C04B28/14 ,  C04B28/34 ,  C04B2111/00836 ,  C04B11/00 ,  C04B20/002 ,  C04B20/008 ,  C04B20/0096 ,  C04B24/04 ,  C04B40/065

摘要： The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, comprising i) a calcium sulfate hemihydrate powder, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 50 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; iii) a non-porous ²-tricalcium phosphate powder; and iv) a porous ²-tricalcium phosphate powder. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.

公开(公告)号：EP3079733A1

公开(公告)日：2016-10-19

申请号：EP14824277.9

申请日：2014-12-12

申请人： Agnovos Healthcare, LLC

发明人： MOSELEY, Jon ,  MACDOUGALL, Jamie ,  HARRIGAN, Katie

IPC分类号： A61L27/12 ,  A61L24/02 ,  C04B35/447

CPC分类号： A61L27/12 ,  A61L24/0015 ,  A61L24/02 ,  A61L27/025 ,  A61L27/3608 ,  A61L27/3641 ,  A61L27/3821 ,  A61L27/3847 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/10 ,  A61L2300/102 ,  A61L2300/112 ,  A61L2300/414 ,  A61L2400/06 ,  A61L2430/02 ,  C04B28/14 ,  C04B28/34 ,  C04B2111/00836 ,  C04B11/00 ,  C04B20/002 ,  C04B20/008 ,  C04B20/0096 ,  C04B24/04 ,  C04B40/065

摘要： The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, comprising i) a calcium sulfate hemihydrate powder, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 50 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; iii) a non-porous ²-tricalcium phosphate powder; and iv) a porous ²-tricalcium phosphate powder. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.