公开(公告)号：EP1434579B1

公开(公告)日：2011-06-08

申请号：EP02769042.9

申请日：2002-10-09

申请人： Amgen Inc.

发明人： FRENKEL, Alexander David ,  LIVELY, Sarah Elizabeth ,  POWERS, Jay P. ,  SMITH, Andrew ,  SUN, Daqing ,  TOMOOKA, Craig ,  WANG, Zhulun

IPC分类号： A61K31/4184 ,  A61K31/437 ,  A61K31/5355 ,  A61K31/45 ,  C07D235/30 ,  C07D471/04 ,  C07D405/12 ,  C07D409/12 ,  C07D403/06 ,  C07D401/06 ,  C07D403/12

CPC分类号： C07D249/08 ,  C07D231/12 ,  C07D233/56 ,  C07D235/30 ,  C07D401/06 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D471/04

摘要： Compounds (I), pharmaceutical compositions thereof are provided that are useful in the treatment of inflammatory and immune-related conditions or disorders. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, immune response regulation and cell proliferation. All definitions are as in the application.