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公开(公告)号：EP2217577A2
公开(公告)日：2010-08-18
申请号：EP08853900.2
申请日：2008-11-26
IPC分类号： C07D249/12 , C07D235/28
CPC分类号： A61K31/4196 , A61K31/7056 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K45/06 , C07D249/12 , C07D249/14 , C07H7/02 , C07H19/06 , C07H19/16
摘要： Described herein are compounds useful in the modulation of blood uric acid levels, formulations containing them and methods of using them. In some embodiments, the compounds described herein are used in the treatment or prevention of disorders related to aberrant levels of uric acid.
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公开(公告)号：EP2217577B1
公开(公告)日：2014-08-06
申请号：EP08853900.2
申请日：2008-11-26
IPC分类号： C07D249/12 , C07D235/28
CPC分类号： A61K31/4196 , A61K31/7056 , A61K31/7068 , A61K31/7072 , A61K31/7076 , A61K45/06 , C07D249/12 , C07D249/14 , C07H7/02 , C07H19/06 , C07H19/16
摘要： Described herein are compounds useful in the modulation of blood uric acid levels, formulations containing them and methods of using them. In some embodiments, the compounds described herein are used in the treatment or prevention of disorders related to aberrant levels of uric acid.
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公开(公告)号：EP2627331A1
公开(公告)日：2013-08-21
申请号：EP10858512.6
申请日：2010-10-15
发明人： QUART, Barry D.
IPC分类号： A61K31/519 , A61K31/426 , A61K31/4196 , A61P1/16 , A61P13/12 , A61P19/02
CPC分类号： A61K31/4196 , A61K31/426 , A61K31/519 , A61K2300/00
摘要： Provided herein are methods of treating gout, treating hyperuricemia, lowering serum uric acid, or the like with compounds of formula (I) have the following structure Further, provided herein are compositions comprising a compound of formula (I).
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公开(公告)号：EP3659601A1
公开(公告)日：2020-06-03
申请号：EP19200639.3
申请日：2011-03-29
发明人： MINER, Jeff , QUART, Barry D. , GIRARDET, Jean-luc
IPC分类号： A61K31/4196 , A61K31/41 , A61P19/06 , A61P19/00 , A61K31/165
摘要： Sodium 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4 H -1,2,4-triazol-3-ylthio)acetate is described. In addition, pharmaceutical compositions and uses of such compositions for the treatment of a variety of diseases and conditions.
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