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公开(公告)号：EP1922307A2
公开(公告)日：2008-05-21
申请号：EP06836069.2
申请日：2006-05-17
发明人： MARLOW, Allison, L. , WALLACE, Eli , SEO, Jeongbeob , LYSSIKATOS, Joseph, P. , YANG, Hong, Woon , BLAKE, Jim , STOREY, Richard, Anthony , BOOTH, Rebecca, Jane , PITTAM, John, David , LEONARD, John , FIELDING, Mark, Richard
IPC分类号： C07D213/84 , C07D213/63 , A61K31/44
CPC分类号： C07D237/24 , C07D213/80 , C07D213/82 , C07D213/84 , C07D213/85
摘要： Disclosed are MEK inhibitors useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
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公开(公告)号：EP1922307B1
公开(公告)日：2011-12-28
申请号：EP06836069.2
申请日：2006-05-17
发明人： MARLOW, Allison, L. , WALLACE, Eli , SEO, Jeongbeob , LYSSIKATOS, Joseph, P. , YANG, Hong, Woon , BLAKE, Jim , STOREY, Richard, Anthony , BOOTH, Rebecca, Jane , PITTAM, John, David , LEONARD, John , FIELDING, Mark, Richard
IPC分类号： C07D237/24 , C07D213/80 , C07D213/82 , C07D213/85 , A61K31/501 , A61P35/00
CPC分类号： C07D237/24 , C07D213/80 , C07D213/82 , C07D213/84 , C07D213/85
摘要： Disclosed are MEK inhibitors useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
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