专利检索 ap:("Array Biopharma, Inc." OR "Genentech, Inc.") AND inv:"TANG, Tony, P." 第 1 页

1.

发明授权
SERINE/THREONINE KINASE INHIBITORS 有权

公开(公告)号：EP3089788B1

公开(公告)日：2018-10-24

申请号：EP14827985.4

申请日：2014-12-29

申请人： Genentech, Inc. , Array Biopharma, Inc.

发明人： BLAKE, James, F. , COOK, Adam , GUNAWARDANA, Indrani, W. , HUNT, Kevin, W. , LYON, Michael , METCALF, Andrew, T. , MOHR, Peter, J. , MORENO, David, A. , NEWHOUSE, Brad , REN, Li , TANG, Tony, P. , THOMAS, Allen, A. , SCHWARZ, Jacob , SCHMIDT, Jane , GAZZARD, Lewis , CHEN, Huifen

IPC分类号： A61P35/00 , A61K31/506 , C07D401/14 , C07D405/14 , C07D403/04 , C07D403/14 , C07D417/14

CPC分类号： A61K31/506 , A61K31/4439 , A61K31/444 , A61K45/06 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D417/14 , C07D471/04

摘要： Compounds of Formula I or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative, pain and inflammatory diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

2.

发明公开
SERINE/THREONINE KINASE INHIBITORS 审中-公开
标题翻译：丝氨酸/苏氨酸激酶抑制剂

公开(公告)号：EP3089788A1

公开(公告)日：2016-11-09

申请号：EP14827985.4

申请日：2014-12-29

申请人： Genentech, Inc. , Array Biopharma, Inc.

发明人： BLAKE, James, F. , COOK, Adam , GUNAWARDANA, Indrani, W. , HUNT, Kevin, W. , LYON, Michael , METCALF, Andrew, T. , MOHR, Peter, J. , MORENO, David, A. , NEWHOUSE, Brad , REN, Li , TANG, Tony, P. , THOMAS, Allen, A. , SCHWARZ, Jacob , SCHMIDT, Jane , GAZZARD, Lewis , CHEN, Huifen

IPC分类号： A61P35/00 , A61K31/506 , C07D401/14 , C07D405/14 , C07D403/04 , C07D403/14 , C07D417/14

CPC分类号： A61K31/506 , A61K31/4439 , A61K31/444 , A61K45/06 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D417/14 , C07D471/04

摘要： Compounds of Formula I or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative, pain and inflammatory diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

摘要翻译： 提供式I化合物或其立体异构体，互变异构体或药学上可接受的盐，其可用于治疗过度增殖性疼痛和炎性疾病。公开了使用式I化合物或其立体异构体，互变异构体或药学上可接受的盐在体外，原位和体内诊断，预防或治疗哺乳动物细胞中的此类病症或相关病理学病症的方法。

3.

发明授权
5H-CYCLOPENTA[D]PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS 有权
标题翻译： -5H-环戊二烯并〔D]嘧啶类AS AKT蛋白激酶抑制剂的

公开(公告)号：EP2250155B1

公开(公告)日：2013-07-03

申请号：EP09701043.3

申请日：2009-01-09

申请人： Array Biopharma, Inc. , Genentech, Inc.

发明人： BANKA, Anna , BENCSIK, Josef R. , BLAKE, James F. , HENTEMANN, Martin F. , KALLAN, Nicholas C. , LIANG, Jun , MITCHELL, Ian S. , SCHLACHTER, Stephen T. , WALLACE, Eli M. , XU, Rui , TANG, Tony, P.

IPC分类号： C07D239/70 , A61K31/517 , A61P35/00 , C07D401/04 , C07D401/10 , C07D409/04 , C07D417/04 , C07D487/04

CPC分类号： C07D401/10 , C07D211/08 , C07D211/46 , C07D239/70 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/10 , C07D409/04 , C07D417/04 , C07D417/10 , C07D487/04

4.

发明公开
5H-CYCLOPENTA[D]PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS 有权
标题翻译： -5H-环戊二烯并〔D]嘧啶类AS AKT蛋白激酶抑制剂的

公开(公告)号：EP2250155A1

公开(公告)日：2010-11-17

申请号：EP09701043.3

申请日：2009-01-09

申请人： Array Biopharma, Inc. , Genentech, Inc.

发明人： BANKA, Anna , BENCSIK, Josef R. , BLAKE, James F. , HENTEMANN, Martin F. , KALLAN, Nicholas C. , LIANG, Jun , MITCHELL, Ian S. , SCHLACHTER, Stephen T. , WALLACE, Eli M. , XU, Rui , TANG, Tony, P.

IPC分类号： C07D239/70 , A61K31/517 , A61P35/00 , C07D401/04 , C07D401/10 , C07D409/04 , C07D417/04 , C07D487/04

CPC分类号： C07D401/10 , C07D211/08 , C07D211/46 , C07D239/70 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/10 , C07D409/04 , C07D417/04 , C07D417/10 , C07D487/04

摘要： Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. Formula (I).