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公开(公告)号:EP3843850A1
公开(公告)日:2021-07-07
申请号:EP19766425.3
申请日:2019-08-29
申请人: Array BioPharma Inc.
发明人: HINKLIN, Ronald Jay , ALLEN, Shelley , BARBOUR, Patrick , COOK, Adam , DAHLKE, Joshua , GAUDINO, John , LAIRD, Ellen , MCNULTY, Oren T. , ZHAO, Qian
IPC分类号: A61P35/00 , C07D471/04 , A61K31/437
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公开(公告)号:EP3523301B1
公开(公告)日:2020-05-27
申请号:EP17787843.6
申请日:2017-10-10
申请人: Array Biopharma Inc.
发明人: ANDREWS, Steven W. , ARONOW, Sean , BLAKE, James F. , BRANDHUBER, Barbara J. , COOK, Adam , HAAS, Julia , JIANG, Yutong , KOLAKOWSKI, Gabrielle R. , MCFADDIN, Elizabeth A. , MCKENNEY, Megan L. , MCNULTY, Oren T. , METCALF, Andrew T. , MORENO, David A. , TANG, Tony P. , REN, Li
IPC分类号: C07D471/04 , A61K31/437 , A61P35/00
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公开(公告)号:EP3867238A1
公开(公告)日:2021-08-25
申请号:EP19801996.0
申请日:2019-10-17
申请人: Array BioPharma Inc.
发明人: BLAKE, James F. , BOYS, Mark Laurence , CHICARELLI, Mark Joseph , COOK, Adam , ELSAYED, Mohamed S. A. , FELL, Jay B. , FISCHER, John P. , HINKLIN, Ronald Jay , MCNULTY, Oren T. , MEJIA, Macedonio J. , RODRIGUEZ, Martha E. , WONG, Christina E.
IPC分类号: C07D401/04 , C07D471/04 , C07D519/00 , A61P35/00 , A61K31/498 , A61K31/4985
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公开(公告)号:EP3523301A1
公开(公告)日:2019-08-14
申请号:EP17787843.6
申请日:2017-10-10
申请人: Array Biopharma Inc.
发明人: ANDREWS, Steven W. , ARONOW, Sean , BLAKE, James F. , BRANDHUBER, Barbara J. , COOK, Adam , HAAS, Julia , JIANG, Yutong , KOLAKOWSKI, Gabrielle R. , MCFADDIN, Elizabeth A. , MCKENNEY, Megan L. , MCNULTY, Oren T. , METCALF, Andrew T. , MORENO, David A. , TANG, Tony P. , REN, Li
IPC分类号: C07D471/04 , A61K31/437 , A61P35/00
摘要: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, X1, X2, X3, X4, Ring D, and E have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.
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公开(公告)号:EP3947367A1
公开(公告)日:2022-02-09
申请号:EP20718387.2
申请日:2020-03-30
发明人: BLAKE, James F. , BOYS, Mark Laurence , CHICARELLI, Mark Joseph , COOK, Adam W. , ELSAYED, Mohamed S. A. , FELL, Jay Bradford , FISCHER, John P. , HINKLIN, Ronald Jay , JIANG, Yutong , MCNULTY, Oren T. , MEJIA, Macedonio J. , RODRIGUEZ, Martha E. , WONG, Christina E.
IPC分类号: C07D401/14 , C07D403/04 , C07D451/04 , C07D471/10 , C07D491/107 , C07D519/00 , A61K31/53 , A61P35/00 , C07D513/10
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公开(公告)号:EP3906234A1
公开(公告)日:2021-11-10
申请号:EP20701499.4
申请日:2020-01-02
申请人: Array BioPharma Inc.
IPC分类号: C07D401/14 , A61P35/00 , A61K31/495 , A61K31/4709
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