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公开(公告)号：EP0204555A3
公开(公告)日：1988-03-02
申请号：EP86304254
申请日：1986-06-04
发明人： Kawakami, Kiyoshi , Tanabe, Toyozi , Nagano, Osamu
CPC分类号： C12P13/02
摘要： @ A method of producing an amide comprises subjecting a nitrile to the action of a microorganism belonging to the genus Rhodococcus and having the ability to hydrate the nitrile, and isolating the resulting amide. The micro-organism is highly active to a wide variety of nitrile even at lowtempera- tures and, in addition, the hydration reaction of nitriles has a high selectivity for the corresponding amides. Accordingly, this method ensures the production of amides in high yield without formation of by-products such as corresponding carboxylic acids.
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公开(公告)号：EP0204555B1
公开(公告)日：1992-05-20
申请号：EP86304254.5
申请日：1986-06-04
发明人： Kawakami, Kiyoshi , Tanabe, Toyozi , Nagano, Osamu
IPC分类号： C12P13/02
CPC分类号： C12P13/02
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3.发明公开Method of producing an amide utilizing a microorganism 失效Verfahren Zur Herstellung eines Amids durch Verwendung eines Mikroorganismus。
公开(公告)号：EP0204555A2
公开(公告)日：1986-12-10
申请号：EP86304254.5
申请日：1986-06-04
发明人： Kawakami, Kiyoshi , Tanabe, Toyozi , Nagano, Osamu
IPC分类号： C12P13/02
CPC分类号： C12P13/02
摘要： @ A method of producing an amide comprises subjecting a nitrile to the action of a microorganism belonging to the genus Rhodococcus and having the ability to hydrate the nitrile, and isolating the resulting amide. The micro-organism is highly active to a wide variety of nitrile even at lowtempera- tures and, in addition, the hydration reaction of nitriles has a high selectivity for the corresponding amides. Accordingly, this method ensures the production of amides in high yield without formation of by-products such as corresponding carboxylic acids.
摘要翻译： 制备酰胺的方法包括使腈受到属于红球菌属的微生物的作用，并具有水合腈的能力，并分离得到的酰胺。 微生物甚至在低温下对多种腈也具有高活性，此外，腈的水合反应对相应的酰胺具有高选择性。 因此，该方法可确保以高产率生产酰胺而不形成副产物如相应的羧酸。
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