专利检索 ap:("AstraZeneca AB") AND inv:"MERIFIELD, Eric" 第 1 页

1.

发明公开
PROCESS 审中-公开
标题翻译：处理

公开(公告)号：EP2707362A1

公开(公告)日：2014-03-19

申请号：EP12722808.8

申请日：2012-05-11

申请人： AstraZeneca AB

发明人： BARNWELL, Neil , CORNWALL, Philip , GILL, Duncan, Michael , HOWELL, Gareth, P. , MEADOWS, Rebecca, Elizabeth , MERIFIELD, Eric , MITCHELL, Christopher, William , MURUGAN, Andiappan , O'KEEFE, Philip , PATEL, Zakariya, Mohamed , ROSE, James, Barry , SINGLETON, John , WITHNALL, Jane

IPC分类号： C07D277/68 , C07D498/10 , C07C309/08

CPC分类号： C07D498/10 , C07C55/07 , C07C309/08 , C07C309/24 , C07D277/68

摘要： Processes for the preparation of the compound of formula (II) and intermediate compounds for use in the processes.

摘要翻译： 制备式（II）化合物和用于该方法的中间体化合物的方法。

2.

发明公开
INTERMEDIATES AND PROCESSES FOR THE PREPARATION OF 4- (ACETYLAMINO) ) -3- [ (4-CHLORO-PHENYL) THIO]-2-METHYL-1H-INDOLE-1-ACETIC ACID 有权
标题翻译：中间体和工艺的制备4-（乙酰基氨基）） - 3 - [（4-氯 - 苯基）硫代] -2-甲基-1H-吲哚-1-ESSIGSÀURE

公开(公告)号：EP2451780A1

公开(公告)日：2012-05-16

申请号：EP10752114.8

申请日：2010-07-05

申请人： AstraZeneca AB

发明人： AINGE, Debra , BUTTERS, Michael , MERIFIELD, Eric , RAMAKRISHNAN, Ravi , RAYAPATI, Ravi Naidu , SHARMA, Parhalad Ray , THOMSON, Colin

IPC分类号： C07D209/08 , C07D209/30 , C07C251/32

CPC分类号： C07D209/40 , C07D209/30 , C07D209/32

摘要： The invention relates to compounds of formula (X), and salts thereof, and their use as intermediates in improved manufacturing processes for the synthesis of pharmaceutical compound of formula (I): X is =0, =N-0H or =N-OC(O)Me; Y is hydrogen, PhS- or
p -chlorophenylsulfanyl; Z is hydrogen or -CH
2 COOR
1 wherein R
1 is selected from hydrogen, optionally substituted hydrocarbyl and optionally substituted heterocyclyl.